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The feasibility of using arterial spin labeling for visualization of non perfused volumes after HIFU treatment in the kidney

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MR guidance of High Intensity Focused Ultrasound (MFgHIFU) ablation offers the possibility to determine if complete tumor ablation has been established based on imaging the non-perfused volume (NPV)... To image the NPV without the use of contrast agents, single shot gradient recalled echo-planar imaging of a coronal slice centered at the ablated region was preceded by slice selective inversion and global inversion (in an alternating fashion)... Figure 1 shows the resulting FAIR images before and after ablation... Figure 2 shows the corresponding CE image (golden standard)... The yellow contour delineates the NPV as seen in the FAIR image... There is a clear correspondence in terms of location and shape in the NPVs as observed in both images... The NPV in the FAIR image is smaller than to the NPV in the CE image, which is, considering the difference in resolution, most likely due to a partial volume effect... The preliminary results show good correspondence between NPVs in the FAIR and CE images and therefore indicate FAIR to be a promising method to monitor the NPV progression in between the sonications... Future work is focused on an improved spatial resolution and a reduction of the required acquisition of the FAIR scans.

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CE image, coronal orientation, The NPV is clearly visible as a black volume. The contour of the FAIR NPV is shown in yellow. Both the location and shape are comparable, unlike the size, which is smaller.
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Figure 2: CE image, coronal orientation, The NPV is clearly visible as a black volume. The contour of the FAIR NPV is shown in yellow. Both the location and shape are comparable, unlike the size, which is smaller.

Mentions: Figure 1 shows the resulting FAIR images before and after ablation. After ablation, the NVP is visible as a dark area at the left of the kidney. Figure 2 shows the corresponding CE image (golden standard). The yellow contour delineates the NPV as seen in the FAIR image. There is a clear correspondence in terms of location and shape in the NPVs as observed in both images. The NPV in the FAIR image is smaller than to the NPV in the CE image, which is, considering the difference in resolution, most likely due to a partial volume effect. The preliminary results show good correspondence between NPVs in the FAIR and CE images and therefore indicate FAIR to be a promising method to monitor the NPV progression in between the sonications. Future work is focused on an improved spatial resolution and a reduction of the required acquisition of the FAIR scans.


The feasibility of using arterial spin labeling for visualization of non perfused volumes after HIFU treatment in the kidney
CE image, coronal orientation, The NPV is clearly visible as a black volume. The contour of the FAIR NPV is shown in yellow. Both the location and shape are comparable, unlike the size, which is smaller.
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC4489789&req=5

Figure 2: CE image, coronal orientation, The NPV is clearly visible as a black volume. The contour of the FAIR NPV is shown in yellow. Both the location and shape are comparable, unlike the size, which is smaller.
Mentions: Figure 1 shows the resulting FAIR images before and after ablation. After ablation, the NVP is visible as a dark area at the left of the kidney. Figure 2 shows the corresponding CE image (golden standard). The yellow contour delineates the NPV as seen in the FAIR image. There is a clear correspondence in terms of location and shape in the NPVs as observed in both images. The NPV in the FAIR image is smaller than to the NPV in the CE image, which is, considering the difference in resolution, most likely due to a partial volume effect. The preliminary results show good correspondence between NPVs in the FAIR and CE images and therefore indicate FAIR to be a promising method to monitor the NPV progression in between the sonications. Future work is focused on an improved spatial resolution and a reduction of the required acquisition of the FAIR scans.

View Article: PubMed Central - HTML

AUTOMATICALLY GENERATED EXCERPT
Please rate it.

MR guidance of High Intensity Focused Ultrasound (MFgHIFU) ablation offers the possibility to determine if complete tumor ablation has been established based on imaging the non-perfused volume (NPV)... To image the NPV without the use of contrast agents, single shot gradient recalled echo-planar imaging of a coronal slice centered at the ablated region was preceded by slice selective inversion and global inversion (in an alternating fashion)... Figure 1 shows the resulting FAIR images before and after ablation... Figure 2 shows the corresponding CE image (golden standard)... The yellow contour delineates the NPV as seen in the FAIR image... There is a clear correspondence in terms of location and shape in the NPVs as observed in both images... The NPV in the FAIR image is smaller than to the NPV in the CE image, which is, considering the difference in resolution, most likely due to a partial volume effect... The preliminary results show good correspondence between NPVs in the FAIR and CE images and therefore indicate FAIR to be a promising method to monitor the NPV progression in between the sonications... Future work is focused on an improved spatial resolution and a reduction of the required acquisition of the FAIR scans.

No MeSH data available.