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Giant parietal lobe infantile gliosarcoma in a 5-year-old child.

Savant HV, Balasubramaniam S, Mahajan V - J Pediatr Neurosci (2015 Apr-Jun)

Bottom Line: A 5-year-old female child came to us with history of fever and loss of appetite since 2 weeks and right sided weakness since 4 days.The patient was given adjuvant therapy following surgery and survived until 9 months following surgery.The etiopathogenesis, treatment modalities and prognosis of GSM is discussed.

View Article: PubMed Central - PubMed

Affiliation: Department of Neurosurgery, BYL Nair Hospital and T.N. Medical College, Mumbai, Maharashtra, India.

ABSTRACT
The relative frequency of pediatric gliosarcoma (GSM) is 1.9% among glioblastomas and 0.5% among pediatric central nervous system tumors. A 5-year-old female child came to us with history of fever and loss of appetite since 2 weeks and right sided weakness since 4 days. Magnetic resonance imaging showed a large heterogeneously enhancing space occupying lesion in the left parieto-occipital region. A parieto-occipital craniotomy with radical excision of tumor was performed. The patient was given adjuvant therapy following surgery and survived until 9 months following surgery. The etiopathogenesis, treatment modalities and prognosis of GSM is discussed.

No MeSH data available.


Related in: MedlinePlus

Enlarged ventricles with ventriculoperitoneal shunt in situ
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Figure 5: Enlarged ventricles with ventriculoperitoneal shunt in situ

Mentions: Postoperatively patient improved in sensorium and right sided limb power. The power was Grade 5/5 by postoperative day 1. The wound healed well and suture removal was done on day 9. Postoperative MRI done was suggestive of complete excision of tumor [Figure 4]. The patient underwent concurrent chemoradiation of 60 Gy along with temozolomide 75 mg/m2 on all days of radiation. The patient had headache and lethargy on postoperative day 15 for which a repeat imaging was done which showed hydrocephalus. We performed a ventriculoperitoneal shunt [Figure 5]. The patient improved following the cerebrospinal fluid diversion procedure. The patient was asymptomatic at 6 months followup. At 9 months following surgery, she got readmitted with drowsiness, decerebration, and respiratory tract infection. She expired even before repeat imaging could be done.


Giant parietal lobe infantile gliosarcoma in a 5-year-old child.

Savant HV, Balasubramaniam S, Mahajan V - J Pediatr Neurosci (2015 Apr-Jun)

Enlarged ventricles with ventriculoperitoneal shunt in situ
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4489064&req=5

Figure 5: Enlarged ventricles with ventriculoperitoneal shunt in situ
Mentions: Postoperatively patient improved in sensorium and right sided limb power. The power was Grade 5/5 by postoperative day 1. The wound healed well and suture removal was done on day 9. Postoperative MRI done was suggestive of complete excision of tumor [Figure 4]. The patient underwent concurrent chemoradiation of 60 Gy along with temozolomide 75 mg/m2 on all days of radiation. The patient had headache and lethargy on postoperative day 15 for which a repeat imaging was done which showed hydrocephalus. We performed a ventriculoperitoneal shunt [Figure 5]. The patient improved following the cerebrospinal fluid diversion procedure. The patient was asymptomatic at 6 months followup. At 9 months following surgery, she got readmitted with drowsiness, decerebration, and respiratory tract infection. She expired even before repeat imaging could be done.

Bottom Line: A 5-year-old female child came to us with history of fever and loss of appetite since 2 weeks and right sided weakness since 4 days.The patient was given adjuvant therapy following surgery and survived until 9 months following surgery.The etiopathogenesis, treatment modalities and prognosis of GSM is discussed.

View Article: PubMed Central - PubMed

Affiliation: Department of Neurosurgery, BYL Nair Hospital and T.N. Medical College, Mumbai, Maharashtra, India.

ABSTRACT
The relative frequency of pediatric gliosarcoma (GSM) is 1.9% among glioblastomas and 0.5% among pediatric central nervous system tumors. A 5-year-old female child came to us with history of fever and loss of appetite since 2 weeks and right sided weakness since 4 days. Magnetic resonance imaging showed a large heterogeneously enhancing space occupying lesion in the left parieto-occipital region. A parieto-occipital craniotomy with radical excision of tumor was performed. The patient was given adjuvant therapy following surgery and survived until 9 months following surgery. The etiopathogenesis, treatment modalities and prognosis of GSM is discussed.

No MeSH data available.


Related in: MedlinePlus