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Giant parietal lobe infantile gliosarcoma in a 5-year-old child.

Savant HV, Balasubramaniam S, Mahajan V - J Pediatr Neurosci (2015 Apr-Jun)

Bottom Line: A 5-year-old female child came to us with history of fever and loss of appetite since 2 weeks and right sided weakness since 4 days.The patient was given adjuvant therapy following surgery and survived until 9 months following surgery.The etiopathogenesis, treatment modalities and prognosis of GSM is discussed.

View Article: PubMed Central - PubMed

Affiliation: Department of Neurosurgery, BYL Nair Hospital and T.N. Medical College, Mumbai, Maharashtra, India.

ABSTRACT
The relative frequency of pediatric gliosarcoma (GSM) is 1.9% among glioblastomas and 0.5% among pediatric central nervous system tumors. A 5-year-old female child came to us with history of fever and loss of appetite since 2 weeks and right sided weakness since 4 days. Magnetic resonance imaging showed a large heterogeneously enhancing space occupying lesion in the left parieto-occipital region. A parieto-occipital craniotomy with radical excision of tumor was performed. The patient was given adjuvant therapy following surgery and survived until 9 months following surgery. The etiopathogenesis, treatment modalities and prognosis of GSM is discussed.

No MeSH data available.


Related in: MedlinePlus

The postcontrast coronal image showing the lesion with mass effect and displacement of the lateral ventricle
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Figure 2: The postcontrast coronal image showing the lesion with mass effect and displacement of the lateral ventricle

Mentions: A 5-year-old female child came to us with history of fever and loss of appetite since 2 weeks and right sided weakness since 4 days. She had history of generalized convulsion 3 months back and one more focal convulsion in right sided limbs 4 days back followed by same side limb weakness. She was lethargic and had preference to sleep but was easily arousable. There was history of headache that was holocranial and with morning exacerbation. On examination, her right sided limb power was 4/5. There was hypertonia and exaggerated reflexes in right sided limbs. Magnetic resonance imaging (MRI) showed a large heterogeneously enhancing space occupying lesion in the left parieto-occipital region causing significant mass effect and midline shift. The lesion was partly solid and partly cystic with rim enhancement and in close proximity to the occipital horn of the lateral ventricle [Figures 1 and 2].


Giant parietal lobe infantile gliosarcoma in a 5-year-old child.

Savant HV, Balasubramaniam S, Mahajan V - J Pediatr Neurosci (2015 Apr-Jun)

The postcontrast coronal image showing the lesion with mass effect and displacement of the lateral ventricle
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4489064&req=5

Figure 2: The postcontrast coronal image showing the lesion with mass effect and displacement of the lateral ventricle
Mentions: A 5-year-old female child came to us with history of fever and loss of appetite since 2 weeks and right sided weakness since 4 days. She had history of generalized convulsion 3 months back and one more focal convulsion in right sided limbs 4 days back followed by same side limb weakness. She was lethargic and had preference to sleep but was easily arousable. There was history of headache that was holocranial and with morning exacerbation. On examination, her right sided limb power was 4/5. There was hypertonia and exaggerated reflexes in right sided limbs. Magnetic resonance imaging (MRI) showed a large heterogeneously enhancing space occupying lesion in the left parieto-occipital region causing significant mass effect and midline shift. The lesion was partly solid and partly cystic with rim enhancement and in close proximity to the occipital horn of the lateral ventricle [Figures 1 and 2].

Bottom Line: A 5-year-old female child came to us with history of fever and loss of appetite since 2 weeks and right sided weakness since 4 days.The patient was given adjuvant therapy following surgery and survived until 9 months following surgery.The etiopathogenesis, treatment modalities and prognosis of GSM is discussed.

View Article: PubMed Central - PubMed

Affiliation: Department of Neurosurgery, BYL Nair Hospital and T.N. Medical College, Mumbai, Maharashtra, India.

ABSTRACT
The relative frequency of pediatric gliosarcoma (GSM) is 1.9% among glioblastomas and 0.5% among pediatric central nervous system tumors. A 5-year-old female child came to us with history of fever and loss of appetite since 2 weeks and right sided weakness since 4 days. Magnetic resonance imaging showed a large heterogeneously enhancing space occupying lesion in the left parieto-occipital region. A parieto-occipital craniotomy with radical excision of tumor was performed. The patient was given adjuvant therapy following surgery and survived until 9 months following surgery. The etiopathogenesis, treatment modalities and prognosis of GSM is discussed.

No MeSH data available.


Related in: MedlinePlus