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Effects of the extract from roasted chicory (Cichorium intybus L.) root containing inulin-type fructans on blood glucose, lipid metabolism, and fecal properties.

Nishimura M, Ohkawara T, Kanayama T, Kitagawa K, Nishimura H, Nishihira J - J Tradit Complement Med (2015)

Bottom Line: The extract from roasted chicory (Cichorium intybus L.; jú jù) root (chicory root extract), which contains inulin-type fructans, has favorable effects including antihyperglycemic and antidyslipidemic effects and the improvement of bowel movement.Although no significant differences in fasting plasma glucose or insulin were observed, hemoglobin A1c was found to decrease by ingesting chicory root extract.However, the level of adiponectin was significantly improved in the chicory root extract group when the baseline and postintervention values were compared.

View Article: PubMed Central - PubMed

Affiliation: Department of Medical Management and Informatics, Hokkaido Information University, Hokkaido, Ebetsu, Japan.

ABSTRACT
The extract from roasted chicory (Cichorium intybus L.; jú jù) root (chicory root extract), which contains inulin-type fructans, has favorable effects including antihyperglycemic and antidyslipidemic effects and the improvement of bowel movement. In this study, we examined the effects of chicory root extract on blood glucose, lipid metabolism, and fecal properties in 47 healthy adult participants in a randomized, double-blind, placebo-controlled study. The participants were divided into a test group that drank chicory root extract and a placebo group that drank nonchicory root extract (ingesting 300 mL daily for 4 weeks). We performed hematological examinations and body composition measurements, and administered a visual analog scale (VAS) questionnaire for fecal properties at the baseline (Week 0) and after the intervention (Week 4) for the two groups. Although no significant differences in fasting plasma glucose or insulin were observed, hemoglobin A1c was found to decrease by ingesting chicory root extract. No intergroup differences in the levels of lipid metabolism parameters were observed. However, the level of adiponectin was significantly improved in the chicory root extract group when the baseline and postintervention values were compared. In addition, chicory root extract tends to improve the VAS score for fecal properties. These results suggest that chicory root extract could delay or prevent the early onset of diabetes mellitus and improve bowel movements.

No MeSH data available.


Related in: MedlinePlus

Changes in the visual analog scale scores of the participants from the baseline to the end of the intervention. (A) Defecation rhythm. (B) Defecation straining. (C) Defecation satisfaction. (D) Fecal odor. Values are means ± standard error.
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fig5: Changes in the visual analog scale scores of the participants from the baseline to the end of the intervention. (A) Defecation rhythm. (B) Defecation straining. (C) Defecation satisfaction. (D) Fecal odor. Values are means ± standard error.

Mentions: Although no significant between-group differences in the VAS scores of defecation straining, defecation satisfaction, and fecal odor were observed in this study, the defecation rhythm was slightly improved by ingesting the chicory extract drink compared with the placebo drink (Fig. 5). Inulin-type fructans cannot be digested easily by salivary and gastric juices because they are polymers composed mainly of β-(2→1) fructosyl fructose linkages.5 In a patient who received radiotherapy, the ingestion of prebiotic mixtures containing inulin, fructooligosaccharide, and maltodextrin was evaluated for changes in the populations of Lactobacillus and Bifidobacterium.10 Although our clinical test evaluated only fecal properties using a VAS, it is necessary to investigate the intestinal bacterial flora in feces after the ingestion of chicory root extract.


Effects of the extract from roasted chicory (Cichorium intybus L.) root containing inulin-type fructans on blood glucose, lipid metabolism, and fecal properties.

Nishimura M, Ohkawara T, Kanayama T, Kitagawa K, Nishimura H, Nishihira J - J Tradit Complement Med (2015)

Changes in the visual analog scale scores of the participants from the baseline to the end of the intervention. (A) Defecation rhythm. (B) Defecation straining. (C) Defecation satisfaction. (D) Fecal odor. Values are means ± standard error.
© Copyright Policy - CC BY-NC-ND
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4488567&req=5

fig5: Changes in the visual analog scale scores of the participants from the baseline to the end of the intervention. (A) Defecation rhythm. (B) Defecation straining. (C) Defecation satisfaction. (D) Fecal odor. Values are means ± standard error.
Mentions: Although no significant between-group differences in the VAS scores of defecation straining, defecation satisfaction, and fecal odor were observed in this study, the defecation rhythm was slightly improved by ingesting the chicory extract drink compared with the placebo drink (Fig. 5). Inulin-type fructans cannot be digested easily by salivary and gastric juices because they are polymers composed mainly of β-(2→1) fructosyl fructose linkages.5 In a patient who received radiotherapy, the ingestion of prebiotic mixtures containing inulin, fructooligosaccharide, and maltodextrin was evaluated for changes in the populations of Lactobacillus and Bifidobacterium.10 Although our clinical test evaluated only fecal properties using a VAS, it is necessary to investigate the intestinal bacterial flora in feces after the ingestion of chicory root extract.

Bottom Line: The extract from roasted chicory (Cichorium intybus L.; jú jù) root (chicory root extract), which contains inulin-type fructans, has favorable effects including antihyperglycemic and antidyslipidemic effects and the improvement of bowel movement.Although no significant differences in fasting plasma glucose or insulin were observed, hemoglobin A1c was found to decrease by ingesting chicory root extract.However, the level of adiponectin was significantly improved in the chicory root extract group when the baseline and postintervention values were compared.

View Article: PubMed Central - PubMed

Affiliation: Department of Medical Management and Informatics, Hokkaido Information University, Hokkaido, Ebetsu, Japan.

ABSTRACT
The extract from roasted chicory (Cichorium intybus L.; jú jù) root (chicory root extract), which contains inulin-type fructans, has favorable effects including antihyperglycemic and antidyslipidemic effects and the improvement of bowel movement. In this study, we examined the effects of chicory root extract on blood glucose, lipid metabolism, and fecal properties in 47 healthy adult participants in a randomized, double-blind, placebo-controlled study. The participants were divided into a test group that drank chicory root extract and a placebo group that drank nonchicory root extract (ingesting 300 mL daily for 4 weeks). We performed hematological examinations and body composition measurements, and administered a visual analog scale (VAS) questionnaire for fecal properties at the baseline (Week 0) and after the intervention (Week 4) for the two groups. Although no significant differences in fasting plasma glucose or insulin were observed, hemoglobin A1c was found to decrease by ingesting chicory root extract. No intergroup differences in the levels of lipid metabolism parameters were observed. However, the level of adiponectin was significantly improved in the chicory root extract group when the baseline and postintervention values were compared. In addition, chicory root extract tends to improve the VAS score for fecal properties. These results suggest that chicory root extract could delay or prevent the early onset of diabetes mellitus and improve bowel movements.

No MeSH data available.


Related in: MedlinePlus