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Sugar Derivatives of Morphine: A New Window for the Development of Potent Anesthetic Drugs.

Jash SK, Gorai D - Nat Prod Bioprospect (2015)

Bottom Line: This review provides a short account of carbohydrate derivatives of an important natural drug, morphine, along with their comparative efficacies as anesthetic agent.Sugar derivatives are found to have more prospect as anesthetic drug than morphine itself owing to their enhanced bioavailability.Synthetic schemes of these sugar derivatives and information on related patents are also included in this manuscript.

View Article: PubMed Central - PubMed

Affiliation: Department of Chemistry, Saldiha College (Affiliated to the University of Burdwan), Saldiha, Bankura, 722 173, West Bengal, India.

ABSTRACT
This review provides a short account of carbohydrate derivatives of an important natural drug, morphine, along with their comparative efficacies as anesthetic agent. Sugar derivatives are found to have more prospect as anesthetic drug than morphine itself owing to their enhanced bioavailability. Synthetic schemes of these sugar derivatives and information on related patents are also included in this manuscript.

No MeSH data available.


Synthesis of 6-methyl-α-d-mannopyranoside (5, M6Man) [9]
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Related In: Results  -  Collection


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Sch3: Synthesis of 6-methyl-α-d-mannopyranoside (5, M6Man) [9]

Mentions: Sugar derivatives of morphine (1)


Sugar Derivatives of Morphine: A New Window for the Development of Potent Anesthetic Drugs.

Jash SK, Gorai D - Nat Prod Bioprospect (2015)

Synthesis of 6-methyl-α-d-mannopyranoside (5, M6Man) [9]
© Copyright Policy - OpenAccess
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4488153&req=5

Sch3: Synthesis of 6-methyl-α-d-mannopyranoside (5, M6Man) [9]
Mentions: Sugar derivatives of morphine (1)

Bottom Line: This review provides a short account of carbohydrate derivatives of an important natural drug, morphine, along with their comparative efficacies as anesthetic agent.Sugar derivatives are found to have more prospect as anesthetic drug than morphine itself owing to their enhanced bioavailability.Synthetic schemes of these sugar derivatives and information on related patents are also included in this manuscript.

View Article: PubMed Central - PubMed

Affiliation: Department of Chemistry, Saldiha College (Affiliated to the University of Burdwan), Saldiha, Bankura, 722 173, West Bengal, India.

ABSTRACT
This review provides a short account of carbohydrate derivatives of an important natural drug, morphine, along with their comparative efficacies as anesthetic agent. Sugar derivatives are found to have more prospect as anesthetic drug than morphine itself owing to their enhanced bioavailability. Synthetic schemes of these sugar derivatives and information on related patents are also included in this manuscript.

No MeSH data available.