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Takayasu's Arteritis with Systemic Lupus Erythematosus: A Rare Association.

Bandyopadhyay D, Ganesan V, Bhar D, Bhowmick D, Sasmal S, Choudhury C, Mukhopadhyay S, Hajra A, Layek M, Karmakar PS - Case Rep Rheumatol (2015)

Bottom Line: We report the case of a 24-year-old nondiabetic, nonhypertensive lady with history of fatigue, dyspnoea and limb claudication.The absence of specific SLE markers in patients with TA who subsequently develop SLE suggests that the coexistence of these conditions may be coincidental.The antiphospholipid syndrome in patients with SLE may mimic the occlusive vasculitis of TA.

View Article: PubMed Central - PubMed

Affiliation: Department of Accident and Emergency, Lady Hardinge Medical College, New Delhi, India.

ABSTRACT
We report the case of a 24-year-old nondiabetic, nonhypertensive lady with history of fatigue, dyspnoea and limb claudication. She has been diagnosed with Takayasu's arteritis. Subsequently she developed rash, alopecia, joint pain, and various other laboratory abnormalities which led to a diagnosis of SLE. Takayasu's arteritis (TA) rarely coexists with systemic lupus erythematosus (SLE). The absence of specific SLE markers in patients with TA who subsequently develop SLE suggests that the coexistence of these conditions may be coincidental. The antiphospholipid syndrome in patients with SLE may mimic the occlusive vasculitis of TA.

No MeSH data available.


Related in: MedlinePlus

Discoid rash over the back.
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fig1: Discoid rash over the back.

Mentions: A 24-year-old unmarried Indian woman consulted her doctor for dyspnoea, fatigue, and upper limb claudication 3 years ago. She was diagnosed as a case of Takayasu's arteritis depending on impalpable pulse and unrecordable blood pressure on left arm, carotid artery bruit on left side, low velocity biphasic flow of all arteries of both upper limbs in Doppler study, and high erythrocyte sedimentation rate (ESR) (60 mm/hr). Antinuclear antibody (ANA) report was negative. She was on daily oral prednisolone (10 mg/day) but she was not adherent to the treatment and follow-up. After 3 years she presented with small and large joints arthritis, malar rash, discoid rash, oral ulcer, nonscarring alopecia, and photosensitivity (Figure 1). Peripheral pulses were not palpable over left brachial and radial artery, and blood pressure was 110/70 mm Hg in the right upper limb and both the lower limbs, not recordable in the left upper limb.


Takayasu's Arteritis with Systemic Lupus Erythematosus: A Rare Association.

Bandyopadhyay D, Ganesan V, Bhar D, Bhowmick D, Sasmal S, Choudhury C, Mukhopadhyay S, Hajra A, Layek M, Karmakar PS - Case Rep Rheumatol (2015)

Discoid rash over the back.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4488004&req=5

fig1: Discoid rash over the back.
Mentions: A 24-year-old unmarried Indian woman consulted her doctor for dyspnoea, fatigue, and upper limb claudication 3 years ago. She was diagnosed as a case of Takayasu's arteritis depending on impalpable pulse and unrecordable blood pressure on left arm, carotid artery bruit on left side, low velocity biphasic flow of all arteries of both upper limbs in Doppler study, and high erythrocyte sedimentation rate (ESR) (60 mm/hr). Antinuclear antibody (ANA) report was negative. She was on daily oral prednisolone (10 mg/day) but she was not adherent to the treatment and follow-up. After 3 years she presented with small and large joints arthritis, malar rash, discoid rash, oral ulcer, nonscarring alopecia, and photosensitivity (Figure 1). Peripheral pulses were not palpable over left brachial and radial artery, and blood pressure was 110/70 mm Hg in the right upper limb and both the lower limbs, not recordable in the left upper limb.

Bottom Line: We report the case of a 24-year-old nondiabetic, nonhypertensive lady with history of fatigue, dyspnoea and limb claudication.The absence of specific SLE markers in patients with TA who subsequently develop SLE suggests that the coexistence of these conditions may be coincidental.The antiphospholipid syndrome in patients with SLE may mimic the occlusive vasculitis of TA.

View Article: PubMed Central - PubMed

Affiliation: Department of Accident and Emergency, Lady Hardinge Medical College, New Delhi, India.

ABSTRACT
We report the case of a 24-year-old nondiabetic, nonhypertensive lady with history of fatigue, dyspnoea and limb claudication. She has been diagnosed with Takayasu's arteritis. Subsequently she developed rash, alopecia, joint pain, and various other laboratory abnormalities which led to a diagnosis of SLE. Takayasu's arteritis (TA) rarely coexists with systemic lupus erythematosus (SLE). The absence of specific SLE markers in patients with TA who subsequently develop SLE suggests that the coexistence of these conditions may be coincidental. The antiphospholipid syndrome in patients with SLE may mimic the occlusive vasculitis of TA.

No MeSH data available.


Related in: MedlinePlus