Limits...
A Case of Spontaneous Tumor Lysis Syndrome in a Patient with Ovarian Cancer.

Okamoto K, Kinoshita T, Shimizu M, Okura I, Kawada A, Mizobuchi K, Ando M - Case Rep Obstet Gynecol (2015)

Bottom Line: We present the novel case of a 62-year-old woman with an ovarian tumor who spontaneously developed TLS.Surgical reduction of the tumor mass vastly improved her condition.As TLS is life-threatening, successful treatments must be seriously considered.

View Article: PubMed Central - PubMed

Affiliation: Department of Obstetrics and Gynecology, Kagawa Rosai Hospital, 3-3-1 Zyotocho, Marugame-shi, Kagawa-ken 763-8502, Japan.

ABSTRACT
Tumor lysis syndrome (TLS) is a potentially life-threating complication of tumors or chemotherapy treatment. TLS commonly occurs in hematological malignancies, but it is very rare in patients with a solid tumor. In cases of solid tumors, TLS usually occurs spontaneously and after the initiation of anticancer therapy, and it has a high mortality rate. We present the novel case of a 62-year-old woman with an ovarian tumor who spontaneously developed TLS. Surgical reduction of the tumor mass vastly improved her condition. She showed no sign of tumor recurrence 8 months after treatment. As TLS is life-threatening, successful treatments must be seriously considered.

No MeSH data available.


Related in: MedlinePlus

Pathological findings. (a) A grade 1 endometrioid adenocarcinoma is characterized by glandular patterns resembling those of the endometrium. (b) Extensive necrosis of the endometrioid carcinoma (left side). (a-b) Hematoxylin and eosin staining (magnification, ×100).
© Copyright Policy - open-access
Related In: Results  -  Collection


getmorefigures.php?uid=PMC4487917&req=5

fig3: Pathological findings. (a) A grade 1 endometrioid adenocarcinoma is characterized by glandular patterns resembling those of the endometrium. (b) Extensive necrosis of the endometrioid carcinoma (left side). (a-b) Hematoxylin and eosin staining (magnification, ×100).

Mentions: Pathologic examination of the neoplasm from the right ovary showed a well-differentiated (grade 1) endometrioid adenocarcinoma with extensive necrosis and capsular rupture (Figure 3). Cytology of the ascitic fluid showed no malignant cells. There were no remarkable changes in the macroscopic appearance of the left ovary or uterus. The final surgical pathologic diagnosis was stage IC ovarian endometrioid adenocarcinoma.


A Case of Spontaneous Tumor Lysis Syndrome in a Patient with Ovarian Cancer.

Okamoto K, Kinoshita T, Shimizu M, Okura I, Kawada A, Mizobuchi K, Ando M - Case Rep Obstet Gynecol (2015)

Pathological findings. (a) A grade 1 endometrioid adenocarcinoma is characterized by glandular patterns resembling those of the endometrium. (b) Extensive necrosis of the endometrioid carcinoma (left side). (a-b) Hematoxylin and eosin staining (magnification, ×100).
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4487917&req=5

fig3: Pathological findings. (a) A grade 1 endometrioid adenocarcinoma is characterized by glandular patterns resembling those of the endometrium. (b) Extensive necrosis of the endometrioid carcinoma (left side). (a-b) Hematoxylin and eosin staining (magnification, ×100).
Mentions: Pathologic examination of the neoplasm from the right ovary showed a well-differentiated (grade 1) endometrioid adenocarcinoma with extensive necrosis and capsular rupture (Figure 3). Cytology of the ascitic fluid showed no malignant cells. There were no remarkable changes in the macroscopic appearance of the left ovary or uterus. The final surgical pathologic diagnosis was stage IC ovarian endometrioid adenocarcinoma.

Bottom Line: We present the novel case of a 62-year-old woman with an ovarian tumor who spontaneously developed TLS.Surgical reduction of the tumor mass vastly improved her condition.As TLS is life-threatening, successful treatments must be seriously considered.

View Article: PubMed Central - PubMed

Affiliation: Department of Obstetrics and Gynecology, Kagawa Rosai Hospital, 3-3-1 Zyotocho, Marugame-shi, Kagawa-ken 763-8502, Japan.

ABSTRACT
Tumor lysis syndrome (TLS) is a potentially life-threating complication of tumors or chemotherapy treatment. TLS commonly occurs in hematological malignancies, but it is very rare in patients with a solid tumor. In cases of solid tumors, TLS usually occurs spontaneously and after the initiation of anticancer therapy, and it has a high mortality rate. We present the novel case of a 62-year-old woman with an ovarian tumor who spontaneously developed TLS. Surgical reduction of the tumor mass vastly improved her condition. She showed no sign of tumor recurrence 8 months after treatment. As TLS is life-threatening, successful treatments must be seriously considered.

No MeSH data available.


Related in: MedlinePlus