Limits...
A Case of Spontaneous Tumor Lysis Syndrome in a Patient with Ovarian Cancer.

Okamoto K, Kinoshita T, Shimizu M, Okura I, Kawada A, Mizobuchi K, Ando M - Case Rep Obstet Gynecol (2015)

Bottom Line: We present the novel case of a 62-year-old woman with an ovarian tumor who spontaneously developed TLS.Surgical reduction of the tumor mass vastly improved her condition.As TLS is life-threatening, successful treatments must be seriously considered.

View Article: PubMed Central - PubMed

Affiliation: Department of Obstetrics and Gynecology, Kagawa Rosai Hospital, 3-3-1 Zyotocho, Marugame-shi, Kagawa-ken 763-8502, Japan.

ABSTRACT
Tumor lysis syndrome (TLS) is a potentially life-threating complication of tumors or chemotherapy treatment. TLS commonly occurs in hematological malignancies, but it is very rare in patients with a solid tumor. In cases of solid tumors, TLS usually occurs spontaneously and after the initiation of anticancer therapy, and it has a high mortality rate. We present the novel case of a 62-year-old woman with an ovarian tumor who spontaneously developed TLS. Surgical reduction of the tumor mass vastly improved her condition. She showed no sign of tumor recurrence 8 months after treatment. As TLS is life-threatening, successful treatments must be seriously considered.

No MeSH data available.


Related in: MedlinePlus

Abdominal plane computed tomography reveals a large pelvic mass with massive ascites that reach the liver and spleen. (a) Sagittal section; (b) frontal section; (c) coronal section.
© Copyright Policy - open-access
Related In: Results  -  Collection


getmorefigures.php?uid=PMC4487917&req=5

fig1: Abdominal plane computed tomography reveals a large pelvic mass with massive ascites that reach the liver and spleen. (a) Sagittal section; (b) frontal section; (c) coronal section.

Mentions: The patient was a 62-year-old nonparous woman with no history of a gynecological disease. She had an enlarged abdomen during the 2 months preceding her visit to our hospital, and she had lower abdominal pain 2 days before her visit. She was transported to our hospital by ambulance and complained of disabling back pain. An abdominal examination revealed a palpable mass in the right lateral region of her abdomen. Transabdominal echography and computed tomography revealed a multilocular-solid tumor (>20 cm in diameter) in her pelvis, and massive ascites extended into the liver and spleen (Figure 1). Blood analysis showed hyperuricemia, hyperkalemia, hyperphosphatemia, and increased levels of plasma creatinine (Table 1). These findings fulfilled the diagnostic criteria of TLS.


A Case of Spontaneous Tumor Lysis Syndrome in a Patient with Ovarian Cancer.

Okamoto K, Kinoshita T, Shimizu M, Okura I, Kawada A, Mizobuchi K, Ando M - Case Rep Obstet Gynecol (2015)

Abdominal plane computed tomography reveals a large pelvic mass with massive ascites that reach the liver and spleen. (a) Sagittal section; (b) frontal section; (c) coronal section.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4487917&req=5

fig1: Abdominal plane computed tomography reveals a large pelvic mass with massive ascites that reach the liver and spleen. (a) Sagittal section; (b) frontal section; (c) coronal section.
Mentions: The patient was a 62-year-old nonparous woman with no history of a gynecological disease. She had an enlarged abdomen during the 2 months preceding her visit to our hospital, and she had lower abdominal pain 2 days before her visit. She was transported to our hospital by ambulance and complained of disabling back pain. An abdominal examination revealed a palpable mass in the right lateral region of her abdomen. Transabdominal echography and computed tomography revealed a multilocular-solid tumor (>20 cm in diameter) in her pelvis, and massive ascites extended into the liver and spleen (Figure 1). Blood analysis showed hyperuricemia, hyperkalemia, hyperphosphatemia, and increased levels of plasma creatinine (Table 1). These findings fulfilled the diagnostic criteria of TLS.

Bottom Line: We present the novel case of a 62-year-old woman with an ovarian tumor who spontaneously developed TLS.Surgical reduction of the tumor mass vastly improved her condition.As TLS is life-threatening, successful treatments must be seriously considered.

View Article: PubMed Central - PubMed

Affiliation: Department of Obstetrics and Gynecology, Kagawa Rosai Hospital, 3-3-1 Zyotocho, Marugame-shi, Kagawa-ken 763-8502, Japan.

ABSTRACT
Tumor lysis syndrome (TLS) is a potentially life-threating complication of tumors or chemotherapy treatment. TLS commonly occurs in hematological malignancies, but it is very rare in patients with a solid tumor. In cases of solid tumors, TLS usually occurs spontaneously and after the initiation of anticancer therapy, and it has a high mortality rate. We present the novel case of a 62-year-old woman with an ovarian tumor who spontaneously developed TLS. Surgical reduction of the tumor mass vastly improved her condition. She showed no sign of tumor recurrence 8 months after treatment. As TLS is life-threatening, successful treatments must be seriously considered.

No MeSH data available.


Related in: MedlinePlus