Limits...
Function of Nucleus Ventralis Posterior Lateralis Thalami in Acupoint Sensitization Phenomena.

Rong PJ, Zhao JJ, Yu LL, Li L, Ben H, Li SY, Zhu B - Evid Based Complement Alternat Med (2015)

Bottom Line: To observe the effect of electroacupuncture (EA) on nucleus ventralis posterior lateralis (VPL) thalami activated by visceral noxious stimulation and to explore the impact of EA on the mechanism of acupoint sensitization under a pathological state of the viscera, EA was applied at bilateral "Zusanli-Shangjuxu" acupoints.The discharge of VPL neurons was response to EA increased after colorectal distension (CRD).The stimulation at "Zusanli-Shangjuxu" acupoints enhanced discharge activity of VPL neurons under CRD-induced visceral pain.

View Article: PubMed Central - PubMed

Affiliation: Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, 16 Nanxiaojie of Dongzhimen, Beijing 100700, China.

ABSTRACT
To observe the effect of electroacupuncture (EA) on nucleus ventralis posterior lateralis (VPL) thalami activated by visceral noxious stimulation and to explore the impact of EA on the mechanism of acupoint sensitization under a pathological state of the viscera, EA was applied at bilateral "Zusanli-Shangjuxu" acupoints. The discharge of VPL neurons was response to EA increased after colorectal distension (CRD). The stimulation at "Zusanli-Shangjuxu" acupoints enhanced discharge activity of VPL neurons under CRD-induced visceral pain. The frequency of neuronal discharge was associated with the pressure gradient of CRD which showed that visceral noxious stimulation may intensify the body's functional response to stimulation at acupoints.

No MeSH data available.


Related in: MedlinePlus

Discharge of VPL neurons before and after CRD.
© Copyright Policy - open-access
Related In: Results  -  Collection


getmorefigures.php?uid=PMC4487708&req=5

fig5: Discharge of VPL neurons before and after CRD.

Mentions: We isolated 54 convergent neurons from the 126 VPL neurons that responded to inputs of mechanical stimulation and systematically observed the discharge of 9 of the 54 convergent neurons caused by different intensities of CRD stimulation. The results showed that, after CRD stimulation ranging from 20 to 80 mmHg, the discharge frequency of VPL neurons significantly increased in rats more than before CRD stimulation (P < 0.01) (Figure 5).


Function of Nucleus Ventralis Posterior Lateralis Thalami in Acupoint Sensitization Phenomena.

Rong PJ, Zhao JJ, Yu LL, Li L, Ben H, Li SY, Zhu B - Evid Based Complement Alternat Med (2015)

Discharge of VPL neurons before and after CRD.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4487708&req=5

fig5: Discharge of VPL neurons before and after CRD.
Mentions: We isolated 54 convergent neurons from the 126 VPL neurons that responded to inputs of mechanical stimulation and systematically observed the discharge of 9 of the 54 convergent neurons caused by different intensities of CRD stimulation. The results showed that, after CRD stimulation ranging from 20 to 80 mmHg, the discharge frequency of VPL neurons significantly increased in rats more than before CRD stimulation (P < 0.01) (Figure 5).

Bottom Line: To observe the effect of electroacupuncture (EA) on nucleus ventralis posterior lateralis (VPL) thalami activated by visceral noxious stimulation and to explore the impact of EA on the mechanism of acupoint sensitization under a pathological state of the viscera, EA was applied at bilateral "Zusanli-Shangjuxu" acupoints.The discharge of VPL neurons was response to EA increased after colorectal distension (CRD).The stimulation at "Zusanli-Shangjuxu" acupoints enhanced discharge activity of VPL neurons under CRD-induced visceral pain.

View Article: PubMed Central - PubMed

Affiliation: Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, 16 Nanxiaojie of Dongzhimen, Beijing 100700, China.

ABSTRACT
To observe the effect of electroacupuncture (EA) on nucleus ventralis posterior lateralis (VPL) thalami activated by visceral noxious stimulation and to explore the impact of EA on the mechanism of acupoint sensitization under a pathological state of the viscera, EA was applied at bilateral "Zusanli-Shangjuxu" acupoints. The discharge of VPL neurons was response to EA increased after colorectal distension (CRD). The stimulation at "Zusanli-Shangjuxu" acupoints enhanced discharge activity of VPL neurons under CRD-induced visceral pain. The frequency of neuronal discharge was associated with the pressure gradient of CRD which showed that visceral noxious stimulation may intensify the body's functional response to stimulation at acupoints.

No MeSH data available.


Related in: MedlinePlus