Limits...
The correlations of glycated hemoglobin and carbohydrate metabolism parameters with heart rate variability in apparently healthy sedentary young male subjects.

Cherkas A, Abrahamovych O, Golota S, Nersesyan A, Pichler C, Serhiyenko V, Knasmüller S, Zarkovic N, Eckl P - Redox Biol (2015)

Bottom Line: We hypothesize that quantitative and qualitative changes of HRV in young subjects may reflect early metabolic derangements responsible for further development of clinically significant disease.HOMA-IR index correlated positively with body weight, visceral fat and BMI (p=0.047, 0.027 and 0.017 respectively).In apparently healthy sedentary subjects HRV reduction correlates with the age advancement, subclinical deteriorations of carbohydrate metabolism and excessive fat accumulation.

View Article: PubMed Central - PubMed

Affiliation: Department of Medicine, Lviv College of Physical Culture, Lviv, Ukraine; Department of Endocrinology, Danylo Halytskyi Lviv National Medical University, Lviv, Ukraine; Department of Internal Medicine #1, Danylo Halytskyi Lviv National Medical University, Lviv, Ukraine. Electronic address: cherkasandriy@yahoo.com.

No MeSH data available.


Related in: MedlinePlus

A scatterplot of glucose/insulin ratio and heart rate in supine position (A); HOMA-IR index and heart rate in supine position (B) in healthy sedentary subjects.
© Copyright Policy - CC BY-NC-ND
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4484544&req=5

f0005: A scatterplot of glucose/insulin ratio and heart rate in supine position (A); HOMA-IR index and heart rate in supine position (B) in healthy sedentary subjects.

Mentions: The correlations of HRV parameters and carbohydrate metabolism are shown in Tables 4 and 5. In supine position (Table 4) the most significant correlations were found for HR, namely negative with FBG, and insulin sensitivity (glucose/insulin ratio) with respective p values 0.013 and <0.001. HOMA-IR index and level of insulin showed positive correlations (p=0.006 and p=0.002 respectively). In contrast pNN50, an important marker of parasympathetic activity, showed negative correlations with HBA1c, insulin and HOMA-IR index, however p values did not reach significance threshold (p>0.05), while the positive correlation with glucose/insulin ratio was significant (p=0.011) (Fig. 1).


The correlations of glycated hemoglobin and carbohydrate metabolism parameters with heart rate variability in apparently healthy sedentary young male subjects.

Cherkas A, Abrahamovych O, Golota S, Nersesyan A, Pichler C, Serhiyenko V, Knasmüller S, Zarkovic N, Eckl P - Redox Biol (2015)

A scatterplot of glucose/insulin ratio and heart rate in supine position (A); HOMA-IR index and heart rate in supine position (B) in healthy sedentary subjects.
© Copyright Policy - CC BY-NC-ND
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4484544&req=5

f0005: A scatterplot of glucose/insulin ratio and heart rate in supine position (A); HOMA-IR index and heart rate in supine position (B) in healthy sedentary subjects.
Mentions: The correlations of HRV parameters and carbohydrate metabolism are shown in Tables 4 and 5. In supine position (Table 4) the most significant correlations were found for HR, namely negative with FBG, and insulin sensitivity (glucose/insulin ratio) with respective p values 0.013 and <0.001. HOMA-IR index and level of insulin showed positive correlations (p=0.006 and p=0.002 respectively). In contrast pNN50, an important marker of parasympathetic activity, showed negative correlations with HBA1c, insulin and HOMA-IR index, however p values did not reach significance threshold (p>0.05), while the positive correlation with glucose/insulin ratio was significant (p=0.011) (Fig. 1).

Bottom Line: We hypothesize that quantitative and qualitative changes of HRV in young subjects may reflect early metabolic derangements responsible for further development of clinically significant disease.HOMA-IR index correlated positively with body weight, visceral fat and BMI (p=0.047, 0.027 and 0.017 respectively).In apparently healthy sedentary subjects HRV reduction correlates with the age advancement, subclinical deteriorations of carbohydrate metabolism and excessive fat accumulation.

View Article: PubMed Central - PubMed

Affiliation: Department of Medicine, Lviv College of Physical Culture, Lviv, Ukraine; Department of Endocrinology, Danylo Halytskyi Lviv National Medical University, Lviv, Ukraine; Department of Internal Medicine #1, Danylo Halytskyi Lviv National Medical University, Lviv, Ukraine. Electronic address: cherkasandriy@yahoo.com.

No MeSH data available.


Related in: MedlinePlus