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A Multicenter, Single-Blind Randomized, Controlled Study of a Volumizing Hyaluronic Acid Filler for Midface Volume Deficit: Patient-Reported Outcomes at 2 Years.

Few J, Cox SE, Paradkar-Mitragotri D, Murphy DK - Aesthet Surg J (2015)

Bottom Line: The effectiveness of Juvéderm Voluma XC was examined from the patient perspective.Increased satisfaction with outer and lower cheek areas and cheek-bone projection and clinically significant improvements in LAFM were noted through month 24.Juvéderm Voluma XC for age-related MVD is effective and well-tolerated from the patient perspective, with results lasting up to 2 years. 4 Therapeutic.

View Article: PubMed Central - PubMed

Affiliation: Dr Few is Clinical Professor of Surgery, Division of Plastic Surgery, University of Chicago Pritzker School of Medicine, Chicago, Illinois. Dr Cox is Assistant Clinical Professor, University of North Carolina, Chapel Hill, North Carolina; and is Supervising Physician, Dermatology Program, Duke University, Durham, North Carolina. Dr Paradkar-Mitragotri was the Manager of Biostatistics at the time of this study and is a former employee of Allergan, Inc., Irvine, California, and Ms Murphy is the Director of Clinical Development Submissions at Allergan, Inc., Irvine, California.

No MeSH data available.


Related in: MedlinePlus

Percentage of patients rating scores of 7 to 10 on the assessment of the look and feel of the midface. (A) Cheeks make me look older than I want to look; (B) Cheeks make me look tired, even when I am not; (C) Cheeks make me look unattractive; (D) Cheeks make me look sad, even when I am not. Scores ranged from 0 to 10, where 0 = not at all, 5 = somewhat, and 10 = very much. Significant improvements in mean score were noted in all categories at 6 and 12 months and in the categories of older and tired at 24 months. *Clinically significant change from baseline in mean satisfaction score (defined a priori as change of ≥3 points).
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SJV050F4: Percentage of patients rating scores of 7 to 10 on the assessment of the look and feel of the midface. (A) Cheeks make me look older than I want to look; (B) Cheeks make me look tired, even when I am not; (C) Cheeks make me look unattractive; (D) Cheeks make me look sad, even when I am not. Scores ranged from 0 to 10, where 0 = not at all, 5 = somewhat, and 10 = very much. Significant improvements in mean score were noted in all categories at 6 and 12 months and in the categories of older and tired at 24 months. *Clinically significant change from baseline in mean satisfaction score (defined a priori as change of ≥3 points).

Mentions: At baseline, a majority of patients rated their cheeks as making them look older, tired, unattractive, and sad. Clinically significant improvements in mean satisfaction scores (change of ≥3 points in mean satisfaction score since baseline) were noted for the categories of older and tired at 6, 12, and 24 months and for the categories of sad and unattractive at 6 and 12 months (Figure 4). In the 5 additional categories, patients noted both at baseline and subsequent time points that their cheeks did not feel hard, lumpy/grainy, or unnatural and did not look uneven or unnatural.Figure 4.


A Multicenter, Single-Blind Randomized, Controlled Study of a Volumizing Hyaluronic Acid Filler for Midface Volume Deficit: Patient-Reported Outcomes at 2 Years.

Few J, Cox SE, Paradkar-Mitragotri D, Murphy DK - Aesthet Surg J (2015)

Percentage of patients rating scores of 7 to 10 on the assessment of the look and feel of the midface. (A) Cheeks make me look older than I want to look; (B) Cheeks make me look tired, even when I am not; (C) Cheeks make me look unattractive; (D) Cheeks make me look sad, even when I am not. Scores ranged from 0 to 10, where 0 = not at all, 5 = somewhat, and 10 = very much. Significant improvements in mean score were noted in all categories at 6 and 12 months and in the categories of older and tired at 24 months. *Clinically significant change from baseline in mean satisfaction score (defined a priori as change of ≥3 points).
© Copyright Policy - creative-commons
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4482214&req=5

SJV050F4: Percentage of patients rating scores of 7 to 10 on the assessment of the look and feel of the midface. (A) Cheeks make me look older than I want to look; (B) Cheeks make me look tired, even when I am not; (C) Cheeks make me look unattractive; (D) Cheeks make me look sad, even when I am not. Scores ranged from 0 to 10, where 0 = not at all, 5 = somewhat, and 10 = very much. Significant improvements in mean score were noted in all categories at 6 and 12 months and in the categories of older and tired at 24 months. *Clinically significant change from baseline in mean satisfaction score (defined a priori as change of ≥3 points).
Mentions: At baseline, a majority of patients rated their cheeks as making them look older, tired, unattractive, and sad. Clinically significant improvements in mean satisfaction scores (change of ≥3 points in mean satisfaction score since baseline) were noted for the categories of older and tired at 6, 12, and 24 months and for the categories of sad and unattractive at 6 and 12 months (Figure 4). In the 5 additional categories, patients noted both at baseline and subsequent time points that their cheeks did not feel hard, lumpy/grainy, or unnatural and did not look uneven or unnatural.Figure 4.

Bottom Line: The effectiveness of Juvéderm Voluma XC was examined from the patient perspective.Increased satisfaction with outer and lower cheek areas and cheek-bone projection and clinically significant improvements in LAFM were noted through month 24.Juvéderm Voluma XC for age-related MVD is effective and well-tolerated from the patient perspective, with results lasting up to 2 years. 4 Therapeutic.

View Article: PubMed Central - PubMed

Affiliation: Dr Few is Clinical Professor of Surgery, Division of Plastic Surgery, University of Chicago Pritzker School of Medicine, Chicago, Illinois. Dr Cox is Assistant Clinical Professor, University of North Carolina, Chapel Hill, North Carolina; and is Supervising Physician, Dermatology Program, Duke University, Durham, North Carolina. Dr Paradkar-Mitragotri was the Manager of Biostatistics at the time of this study and is a former employee of Allergan, Inc., Irvine, California, and Ms Murphy is the Director of Clinical Development Submissions at Allergan, Inc., Irvine, California.

No MeSH data available.


Related in: MedlinePlus