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Cardiovascular magnetic resonance compatible physical model of the left ventricle for multi-modality characterization of wall motion and hemodynamics.

Okafor IU, Santhanakrishnan A, Chaffins BD, Mirabella L, Oshinski JN, Yoganathan AP - J Cardiovasc Magn Reson (2015)

Bottom Line: DPIV and PC-CMR results of the center plane flow within the ventricle matched, both qualitatively and quantitatively, with flow from the atrium into the LV having a velocity of about 1.15 m/s for both modalities.The mean difference between CMR and SP was 5.5 ± 3.7%.The model presented here can thus be used for the purposes of: (a) acquiring CMR data for validation of FSI simulations, (b) determining accuracy of cine-CMR reconstruction methods, and

View Article: PubMed Central - PubMed

Affiliation: School of Chemical & Biomolecular Engineering, Georgia Institute of Technology, Atlanta, GA, USA. iokafor3@gatech.edu.

No MeSH data available.


Cine-CMR measurements of the LV physical model wall motion: (a) shows the orientation of the 15 planes (or short axis slices) used for acquiring anatomical cine-CMR images for quantifying wall motion, and (b) shows representative images across both systolic and diastolic phases of the cardiac cycle (time point is indicated as percentage of cardiac cycle period). For (b), 128 phases were acquired across the cardiac cycle, with 0 mm spacing between slices.
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Fig5: Cine-CMR measurements of the LV physical model wall motion: (a) shows the orientation of the 15 planes (or short axis slices) used for acquiring anatomical cine-CMR images for quantifying wall motion, and (b) shows representative images across both systolic and diastolic phases of the cardiac cycle (time point is indicated as percentage of cardiac cycle period). For (b), 128 phases were acquired across the cardiac cycle, with 0 mm spacing between slices.

Mentions: The heart model was examined on a 3 T Siemens scanner to evaluate LV wall motion. Contiguous short axis images slices were acquired using a cine balanced steady-state free precession (SSFP) sequence. A six-element phase array body coil along with elements from the spine coil built into the table. The acquisition sequence was retrospectively ECG-gated using an external TTL pulse sent to an ECG-pulse conversion box which triggered the CMR scanner through the ECG gating module. An acceleration factor of 2 was used using the GRAPPA technique. The SSFP cine images were acquired with an in-plane resolution of 1.2 by 1.2 mm, a slice thickness of 6 mm, and a reconstructed temporal resolution of 7 ms (128 frames/cycle). Two signal averages were acquired resulting in an acquisition time of 3:28 seconds per slice for the PC-CMR sequence. TE (echo time) = 3.3 milliseconds. Two segments were acquired per cardiac phase per heartbeat, yielding an effect TR (temporal resolution) of 24 milliseconds. To cover the entire LV, 15 slices were acquired with no gap. Figure 5a shows the orientation at which the slices were acquired.Fig. 5


Cardiovascular magnetic resonance compatible physical model of the left ventricle for multi-modality characterization of wall motion and hemodynamics.

Okafor IU, Santhanakrishnan A, Chaffins BD, Mirabella L, Oshinski JN, Yoganathan AP - J Cardiovasc Magn Reson (2015)

Cine-CMR measurements of the LV physical model wall motion: (a) shows the orientation of the 15 planes (or short axis slices) used for acquiring anatomical cine-CMR images for quantifying wall motion, and (b) shows representative images across both systolic and diastolic phases of the cardiac cycle (time point is indicated as percentage of cardiac cycle period). For (b), 128 phases were acquired across the cardiac cycle, with 0 mm spacing between slices.
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC4482204&req=5

Fig5: Cine-CMR measurements of the LV physical model wall motion: (a) shows the orientation of the 15 planes (or short axis slices) used for acquiring anatomical cine-CMR images for quantifying wall motion, and (b) shows representative images across both systolic and diastolic phases of the cardiac cycle (time point is indicated as percentage of cardiac cycle period). For (b), 128 phases were acquired across the cardiac cycle, with 0 mm spacing between slices.
Mentions: The heart model was examined on a 3 T Siemens scanner to evaluate LV wall motion. Contiguous short axis images slices were acquired using a cine balanced steady-state free precession (SSFP) sequence. A six-element phase array body coil along with elements from the spine coil built into the table. The acquisition sequence was retrospectively ECG-gated using an external TTL pulse sent to an ECG-pulse conversion box which triggered the CMR scanner through the ECG gating module. An acceleration factor of 2 was used using the GRAPPA technique. The SSFP cine images were acquired with an in-plane resolution of 1.2 by 1.2 mm, a slice thickness of 6 mm, and a reconstructed temporal resolution of 7 ms (128 frames/cycle). Two signal averages were acquired resulting in an acquisition time of 3:28 seconds per slice for the PC-CMR sequence. TE (echo time) = 3.3 milliseconds. Two segments were acquired per cardiac phase per heartbeat, yielding an effect TR (temporal resolution) of 24 milliseconds. To cover the entire LV, 15 slices were acquired with no gap. Figure 5a shows the orientation at which the slices were acquired.Fig. 5

Bottom Line: DPIV and PC-CMR results of the center plane flow within the ventricle matched, both qualitatively and quantitatively, with flow from the atrium into the LV having a velocity of about 1.15 m/s for both modalities.The mean difference between CMR and SP was 5.5 ± 3.7%.The model presented here can thus be used for the purposes of: (a) acquiring CMR data for validation of FSI simulations, (b) determining accuracy of cine-CMR reconstruction methods, and

View Article: PubMed Central - PubMed

Affiliation: School of Chemical & Biomolecular Engineering, Georgia Institute of Technology, Atlanta, GA, USA. iokafor3@gatech.edu.

No MeSH data available.