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The effectiveness of psychosocial interventions for anxiety in children and adolescents with autism spectrum disorder: a systematic review and meta-analysis.

Kreslins A, Robertson AE, Melville C - Child Adolesc Psychiatry Ment Health (2015)

Bottom Line: Clinician- and parent-reported outcome measures showed that psychosocial interventions were superior to waitlist and treatment-as-usual control conditions at post-treatment.However, the results of self-reported outcome measures failed to reach significance.The sensitivity analyses did not significantly change these results and the subgroup analysis indicated that individual treatment was more effective than group treatment.

View Article: PubMed Central - PubMed

Affiliation: Institute of Health and Wellbeing, University of Glasgow, 1st Floor Admin Building Gartnavel Royal Hospital, 1055 Great Western Road, Glasgow, G12 0XH, Scotland.

ABSTRACT
Anxiety is a common problem in children and adolescents with autism spectrum disorder (ASD). This meta-analysis aimed to systematically evaluate the evidence for the use of psychosocial interventions to manage anxiety in this population. Cognitive behavioural therapy (CBT) was the primary intervention modality studied. A comprehensive systematic search and study selection process was conducted. Separate statistical analyses were carried out for clinician-, parent-, and self-reported outcome measures. Sensitivity analyses were conducted by removing any outlying studies and any studies that did not use a CBT intervention. A subgroup analysis was performed to compare individual and group delivery of treatment. Ten randomised control trials involving a total of 470 participants were included. The overall SMD was d = 1.05 (95 % CI 0.45, 1.65; z = 3.45, p = 0.0006) for clinician- reported outcome measures; d = 1.00 (95%CI 0.21, 1.80; z = 2.47, p = 0.01) for parent-reported outcome measures; and d = 0.65 (95%CI -0.10, 1.07; z = 1.63, p = 0.10) for self-reported outcome measures. Clinician- and parent-reported outcome measures showed that psychosocial interventions were superior to waitlist and treatment-as-usual control conditions at post-treatment. However, the results of self-reported outcome measures failed to reach significance. The sensitivity analyses did not significantly change these results and the subgroup analysis indicated that individual treatment was more effective than group treatment. The main limitations of this review were the small number of included studies as well as the clinical and methodological variability between studies.

No MeSH data available.


Related in: MedlinePlus

PRISMA flow diagram of study selection
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Related In: Results  -  Collection

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Fig1: PRISMA flow diagram of study selection

Mentions: The search of the databases yielded 1847 results, 575 of which were duplicates. One paper was added which had not yet been published at the time of the search [37]. 1272 records were screened based on the title and abstract, 1242 of which were excluded. An additional three were excluded due to a lack of full-text availability. Twenty-seven full-text papers were assessed for eligibility. A total of ten studies met the inclusion criteria for this review. A flow diagram of the study selection is shown in Fig. 1.Fig. 1


The effectiveness of psychosocial interventions for anxiety in children and adolescents with autism spectrum disorder: a systematic review and meta-analysis.

Kreslins A, Robertson AE, Melville C - Child Adolesc Psychiatry Ment Health (2015)

PRISMA flow diagram of study selection
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC4482189&req=5

Fig1: PRISMA flow diagram of study selection
Mentions: The search of the databases yielded 1847 results, 575 of which were duplicates. One paper was added which had not yet been published at the time of the search [37]. 1272 records were screened based on the title and abstract, 1242 of which were excluded. An additional three were excluded due to a lack of full-text availability. Twenty-seven full-text papers were assessed for eligibility. A total of ten studies met the inclusion criteria for this review. A flow diagram of the study selection is shown in Fig. 1.Fig. 1

Bottom Line: Clinician- and parent-reported outcome measures showed that psychosocial interventions were superior to waitlist and treatment-as-usual control conditions at post-treatment.However, the results of self-reported outcome measures failed to reach significance.The sensitivity analyses did not significantly change these results and the subgroup analysis indicated that individual treatment was more effective than group treatment.

View Article: PubMed Central - PubMed

Affiliation: Institute of Health and Wellbeing, University of Glasgow, 1st Floor Admin Building Gartnavel Royal Hospital, 1055 Great Western Road, Glasgow, G12 0XH, Scotland.

ABSTRACT
Anxiety is a common problem in children and adolescents with autism spectrum disorder (ASD). This meta-analysis aimed to systematically evaluate the evidence for the use of psychosocial interventions to manage anxiety in this population. Cognitive behavioural therapy (CBT) was the primary intervention modality studied. A comprehensive systematic search and study selection process was conducted. Separate statistical analyses were carried out for clinician-, parent-, and self-reported outcome measures. Sensitivity analyses were conducted by removing any outlying studies and any studies that did not use a CBT intervention. A subgroup analysis was performed to compare individual and group delivery of treatment. Ten randomised control trials involving a total of 470 participants were included. The overall SMD was d = 1.05 (95 % CI 0.45, 1.65; z = 3.45, p = 0.0006) for clinician- reported outcome measures; d = 1.00 (95%CI 0.21, 1.80; z = 2.47, p = 0.01) for parent-reported outcome measures; and d = 0.65 (95%CI -0.10, 1.07; z = 1.63, p = 0.10) for self-reported outcome measures. Clinician- and parent-reported outcome measures showed that psychosocial interventions were superior to waitlist and treatment-as-usual control conditions at post-treatment. However, the results of self-reported outcome measures failed to reach significance. The sensitivity analyses did not significantly change these results and the subgroup analysis indicated that individual treatment was more effective than group treatment. The main limitations of this review were the small number of included studies as well as the clinical and methodological variability between studies.

No MeSH data available.


Related in: MedlinePlus