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Fabrication and robotization of ultrasensitive plasmonic nanosensors for molecule detection with Raman scattering.

Xu X, Kim K, Liu C, Fan D - Sensors (Basel) (2015)

Bottom Line: Our nanosensors, consisting of tri-layer nanocapsule structures, are ultrasensitive, well reproducible, and can be robotized by either electric or magnetic tweezers.Three applications using such SERS nanosensors were demonstrated, including location predictable detection, single-cell bioanalysis, and tunable molecule release and monitoring.The integration of SERS and nanoelectromechanical system (NEMS) devices is innovative in both device concept and fabrication, and could potentially inspire a new device scheme for various bio-relevant applications.

View Article: PubMed Central - PubMed

Affiliation: Materials Science and Engineering Program, the University of Texas at Austin, Austin, TX 78712, USA. xxu.uta@gmail.com.

ABSTRACT
In this work, we introduce the history and mechanisms of surface enhanced Raman scattering (SERS), discuss various techniques for fabrication of state-of-the-art SERS substrates, and review recent work on robotizing plasmonic nanoparticles, especially, the efforts we made on fabrication, characterization, and robotization of Raman nanosensors by design. Our nanosensors, consisting of tri-layer nanocapsule structures, are ultrasensitive, well reproducible, and can be robotized by either electric or magnetic tweezers. Three applications using such SERS nanosensors were demonstrated, including location predictable detection, single-cell bioanalysis, and tunable molecule release and monitoring. The integration of SERS and nanoelectromechanical system (NEMS) devices is innovative in both device concept and fabrication, and could potentially inspire a new device scheme for various bio-relevant applications.

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Structure of a tri-layer nanocapsule [71]. With permission from [71].
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sensors-15-10422-f005: Structure of a tri-layer nanocapsule [71]. With permission from [71].

Mentions: In our recent research, we explored to resolve the aforementioned problems by rational design, fabrication and robotization of a unique type of nanocapsule SERS sensors (Figure 5).


Fabrication and robotization of ultrasensitive plasmonic nanosensors for molecule detection with Raman scattering.

Xu X, Kim K, Liu C, Fan D - Sensors (Basel) (2015)

Structure of a tri-layer nanocapsule [71]. With permission from [71].
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4481927&req=5

sensors-15-10422-f005: Structure of a tri-layer nanocapsule [71]. With permission from [71].
Mentions: In our recent research, we explored to resolve the aforementioned problems by rational design, fabrication and robotization of a unique type of nanocapsule SERS sensors (Figure 5).

Bottom Line: Our nanosensors, consisting of tri-layer nanocapsule structures, are ultrasensitive, well reproducible, and can be robotized by either electric or magnetic tweezers.Three applications using such SERS nanosensors were demonstrated, including location predictable detection, single-cell bioanalysis, and tunable molecule release and monitoring.The integration of SERS and nanoelectromechanical system (NEMS) devices is innovative in both device concept and fabrication, and could potentially inspire a new device scheme for various bio-relevant applications.

View Article: PubMed Central - PubMed

Affiliation: Materials Science and Engineering Program, the University of Texas at Austin, Austin, TX 78712, USA. xxu.uta@gmail.com.

ABSTRACT
In this work, we introduce the history and mechanisms of surface enhanced Raman scattering (SERS), discuss various techniques for fabrication of state-of-the-art SERS substrates, and review recent work on robotizing plasmonic nanoparticles, especially, the efforts we made on fabrication, characterization, and robotization of Raman nanosensors by design. Our nanosensors, consisting of tri-layer nanocapsule structures, are ultrasensitive, well reproducible, and can be robotized by either electric or magnetic tweezers. Three applications using such SERS nanosensors were demonstrated, including location predictable detection, single-cell bioanalysis, and tunable molecule release and monitoring. The integration of SERS and nanoelectromechanical system (NEMS) devices is innovative in both device concept and fabrication, and could potentially inspire a new device scheme for various bio-relevant applications.

Show MeSH