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Effect of a single injection of gonadotropin-releasing hormone (GnRH) and human chorionic gonadotropin (hCG) on testicular blood flow measured by color doppler ultrasonography in male Shiba goats.

Samir H, Sasaki K, Ahmed E, Karen A, Nagaoka K, El Sayed M, Taya K, Watanabe G - J. Vet. Med. Sci. (2015)

Bottom Line: The results indicated an increase in testicular blood flow in both groups, as RI and PI decreased significantly (P<0.05), but this increase was significant higher and earlier in hCG group (1 hr) than in the GnRH group (2 hr).A high correlation was found for RI and PI with both T (RI, r= -0.862; PI, r= -0.707) and INH in the GnRH group (RI, r=0.661; PI, r=0.701).However, a significant (P<0.05) correlation was found between E2 and both RI (r= -0.610) and PI (r= -0.763) in hCG group.

View Article: PubMed Central - PubMed

Affiliation: Laboratory of Veterinary Physiology, Tokyo University of Agriculture and Technology, Tokyo183-8509, Japan.

ABSTRACT
Although color Doppler ultrasonography has been used to evaluate testicular blood flow in many species, very little has been done in goat. Eight male Shiba goats were exposed to a single intramuscular injection of either gonadotropin-releasing hormone (GnRH group; 1 µg/kg BW) or human chorionic gonadotropin (hCG group; 25 IU/kg BW). Plasma testosterone (T), estradiol (E2) and inhibin (INH) were measured just before (0 hr) and at different intervals post injection by radioimmunoassay. Testis volume (TV) and Doppler indices, such as resistive index (RI) and pulsatility index (PI) of the supratesticular artery, were measured by B-mode and color Doppler ultrasonography, respectively. The results indicated an increase in testicular blood flow in both groups, as RI and PI decreased significantly (P<0.05), but this increase was significant higher and earlier in hCG group (1 hr) than in the GnRH group (2 hr). A high correlation was found for RI and PI with both T (RI, r= -0.862; PI, r= -0.707) and INH in the GnRH group (RI, r=0.661; PI, r=0.701). However, a significant (P<0.05) correlation was found between E2 and both RI (r= -0.610) and PI (r= -0.763) in hCG group. In addition, TV significantly increased and was highly correlated with RI in both groups (GnRH, r= -0.718; hCG, r= -0.779). In conclusion, hCG and GnRH may improve testicular blood flow and TV in Shiba goats.

No MeSH data available.


Related in: MedlinePlus

The results of ultrasonographic examination of male Shiba goats showed changes intestis volume (TV) after injection of GnRH or hCG. Results are presented as the mean ±SEM. a, b Values are significantly different (P<0.05)compared with 0 hr in the GnRH and hCG groups, respectively. (Note: No significantdifference was found between the groups at any time during the study.)
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fig_005: The results of ultrasonographic examination of male Shiba goats showed changes intestis volume (TV) after injection of GnRH or hCG. Results are presented as the mean ±SEM. a, b Values are significantly different (P<0.05)compared with 0 hr in the GnRH and hCG groups, respectively. (Note: No significantdifference was found between the groups at any time during the study.)

Mentions: Testicular volume (TV) measurements by B-mode ultrasonography: Both theGnRH and hCG groups showed significant changes in TV compared with 0 hr. However, we did notfind any significant difference (P>0.05) between them at any time duringthe period of study. Similar to the RI changes, a faster increase of TV was observed in thehCG group (I hr) compared with in the GnRH group (2 hr) (Fig. 5Fig. 5.


Effect of a single injection of gonadotropin-releasing hormone (GnRH) and human chorionic gonadotropin (hCG) on testicular blood flow measured by color doppler ultrasonography in male Shiba goats.

Samir H, Sasaki K, Ahmed E, Karen A, Nagaoka K, El Sayed M, Taya K, Watanabe G - J. Vet. Med. Sci. (2015)

The results of ultrasonographic examination of male Shiba goats showed changes intestis volume (TV) after injection of GnRH or hCG. Results are presented as the mean ±SEM. a, b Values are significantly different (P<0.05)compared with 0 hr in the GnRH and hCG groups, respectively. (Note: No significantdifference was found between the groups at any time during the study.)
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4478734&req=5

fig_005: The results of ultrasonographic examination of male Shiba goats showed changes intestis volume (TV) after injection of GnRH or hCG. Results are presented as the mean ±SEM. a, b Values are significantly different (P<0.05)compared with 0 hr in the GnRH and hCG groups, respectively. (Note: No significantdifference was found between the groups at any time during the study.)
Mentions: Testicular volume (TV) measurements by B-mode ultrasonography: Both theGnRH and hCG groups showed significant changes in TV compared with 0 hr. However, we did notfind any significant difference (P>0.05) between them at any time duringthe period of study. Similar to the RI changes, a faster increase of TV was observed in thehCG group (I hr) compared with in the GnRH group (2 hr) (Fig. 5Fig. 5.

Bottom Line: The results indicated an increase in testicular blood flow in both groups, as RI and PI decreased significantly (P<0.05), but this increase was significant higher and earlier in hCG group (1 hr) than in the GnRH group (2 hr).A high correlation was found for RI and PI with both T (RI, r= -0.862; PI, r= -0.707) and INH in the GnRH group (RI, r=0.661; PI, r=0.701).However, a significant (P<0.05) correlation was found between E2 and both RI (r= -0.610) and PI (r= -0.763) in hCG group.

View Article: PubMed Central - PubMed

Affiliation: Laboratory of Veterinary Physiology, Tokyo University of Agriculture and Technology, Tokyo183-8509, Japan.

ABSTRACT
Although color Doppler ultrasonography has been used to evaluate testicular blood flow in many species, very little has been done in goat. Eight male Shiba goats were exposed to a single intramuscular injection of either gonadotropin-releasing hormone (GnRH group; 1 µg/kg BW) or human chorionic gonadotropin (hCG group; 25 IU/kg BW). Plasma testosterone (T), estradiol (E2) and inhibin (INH) were measured just before (0 hr) and at different intervals post injection by radioimmunoassay. Testis volume (TV) and Doppler indices, such as resistive index (RI) and pulsatility index (PI) of the supratesticular artery, were measured by B-mode and color Doppler ultrasonography, respectively. The results indicated an increase in testicular blood flow in both groups, as RI and PI decreased significantly (P<0.05), but this increase was significant higher and earlier in hCG group (1 hr) than in the GnRH group (2 hr). A high correlation was found for RI and PI with both T (RI, r= -0.862; PI, r= -0.707) and INH in the GnRH group (RI, r=0.661; PI, r=0.701). However, a significant (P<0.05) correlation was found between E2 and both RI (r= -0.610) and PI (r= -0.763) in hCG group. In addition, TV significantly increased and was highly correlated with RI in both groups (GnRH, r= -0.718; hCG, r= -0.779). In conclusion, hCG and GnRH may improve testicular blood flow and TV in Shiba goats.

No MeSH data available.


Related in: MedlinePlus