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Fast and accurate Monte Carlo modeling of a kilovoltage X-ray therapy unit using a photon-source approximation for treatment planning in complex media.

Zeinali-Rafsanjani B, Mosleh-Shirazi MA, Faghihi R, Karbasi S, Mosalaei A - J Med Phys (2015 Apr-Jun)

Bottom Line: The measured and computed first and second HVLs were 3.8, 10.3 mm Al and 3.8, 10.6 mm Al, respectively.In the Rando phantom, differences for majority of data points were within 2%.The proposed model offered an approximately 9500-fold reduced run time compared to the conventional full simulation.

View Article: PubMed Central - PubMed

Affiliation: Department of Medical Radiation, School of Mechanical Engineering, Shiraz University, Shiraz, Iran.

ABSTRACT
To accurately recompute dose distributions in chest-wall radiotherapy with 120 kVp kilovoltage X-rays, an MCNP4C Monte Carlo model is presented using a fast method that obviates the need to fully model the tube components. To validate the model, half-value layer (HVL), percentage depth doses (PDDs) and beam profiles were measured. Dose measurements were performed for a more complex situation using thermoluminescence dosimeters (TLDs) placed within a Rando phantom. The measured and computed first and second HVLs were 3.8, 10.3 mm Al and 3.8, 10.6 mm Al, respectively. The differences between measured and calculated PDDs and beam profiles in water were within 2 mm/2% for all data points. In the Rando phantom, differences for majority of data points were within 2%. The proposed model offered an approximately 9500-fold reduced run time compared to the conventional full simulation. The acceptable agreement, based on international criteria, between the simulations and the measurements validates the accuracy of the model for its use in treatment planning and radiobiological modeling studies of superficial therapies including chest-wall irradiation using kilovoltage beam.

No MeSH data available.


Comparison of beam dose profiles resulting from experimental measurements and Monte Carlo simulations in a 14 × 14 cm2 field at depths of 2 and 5 cm in the inline direction
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Figure 4: Comparison of beam dose profiles resulting from experimental measurements and Monte Carlo simulations in a 14 × 14 cm2 field at depths of 2 and 5 cm in the inline direction


Fast and accurate Monte Carlo modeling of a kilovoltage X-ray therapy unit using a photon-source approximation for treatment planning in complex media.

Zeinali-Rafsanjani B, Mosleh-Shirazi MA, Faghihi R, Karbasi S, Mosalaei A - J Med Phys (2015 Apr-Jun)

Comparison of beam dose profiles resulting from experimental measurements and Monte Carlo simulations in a 14 × 14 cm2 field at depths of 2 and 5 cm in the inline direction
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4478648&req=5

Figure 4: Comparison of beam dose profiles resulting from experimental measurements and Monte Carlo simulations in a 14 × 14 cm2 field at depths of 2 and 5 cm in the inline direction
Bottom Line: The measured and computed first and second HVLs were 3.8, 10.3 mm Al and 3.8, 10.6 mm Al, respectively.In the Rando phantom, differences for majority of data points were within 2%.The proposed model offered an approximately 9500-fold reduced run time compared to the conventional full simulation.

View Article: PubMed Central - PubMed

Affiliation: Department of Medical Radiation, School of Mechanical Engineering, Shiraz University, Shiraz, Iran.

ABSTRACT
To accurately recompute dose distributions in chest-wall radiotherapy with 120 kVp kilovoltage X-rays, an MCNP4C Monte Carlo model is presented using a fast method that obviates the need to fully model the tube components. To validate the model, half-value layer (HVL), percentage depth doses (PDDs) and beam profiles were measured. Dose measurements were performed for a more complex situation using thermoluminescence dosimeters (TLDs) placed within a Rando phantom. The measured and computed first and second HVLs were 3.8, 10.3 mm Al and 3.8, 10.6 mm Al, respectively. The differences between measured and calculated PDDs and beam profiles in water were within 2 mm/2% for all data points. In the Rando phantom, differences for majority of data points were within 2%. The proposed model offered an approximately 9500-fold reduced run time compared to the conventional full simulation. The acceptable agreement, based on international criteria, between the simulations and the measurements validates the accuracy of the model for its use in treatment planning and radiobiological modeling studies of superficial therapies including chest-wall irradiation using kilovoltage beam.

No MeSH data available.