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Premature Graying of Hair: An Independent Risk Marker for Coronary Artery Disease in Smokers - A Retrospective Case Control Study.

Aggarwal A, Srivastava S, Agarwal MP, Dwivedi S - Ethiop J Health Sci (2015)

Bottom Line: All subjects were males.The carotid intima media thickness, dyslipidemia and blood pressure were significantly higher in group I and II as compared to group III.When the groups were compared for graying of hair, it was found that the group II (i.e., smokers and CAD) had maximum prevalence of graying which was significantly higher than the control as well as smoker groups.

View Article: PubMed Central - PubMed

Affiliation: Department of Medicine, University College of Medical Sciences & GTB Hospital, Delhi, India.

ABSTRACT

Background: Premature graying of hair as a risk marker among young smokers has a potential of identifying coronary artery disease (CAD) at a very early stage. There is absence of literature that assesses premature graying of hair as an independent marker of CAD in smokers.

Material and methods: The present single-centre case control study enrolled a total of 62 consecutive chronic smokers (≤ 45 years) (Group I) and 60 consecutive young CAD patients (≤45 years) who were chronic smokers (Group II). Another group comprising of 114 patients (≤45 years) having no smoking history and no cardiac ailments either (Group III) was enrolled as control population. All subjects were males. A detailed history and clinical examination regarding conventional coronary risk factors and carotid intima media thickness was done in both groups.

Results: The carotid intima media thickness, dyslipidemia and blood pressure were significantly higher in group I and II as compared to group III. When the groups were compared for graying of hair, it was found that the group II (i.e., smokers and CAD) had maximum prevalence of graying which was significantly higher than the control as well as smoker groups. The presence of premature graying of hair was associated with 3.24 times the risk of CAD on multiple logistic regression analysis.

Conclusion: The presence of premature graying of hair was associated with an increased risk of CAD in young smokers. Premature graying of hair can be used as preliminary evidence by clinicians for classifying patients at risk for premature CAD especially in smokers.

No MeSH data available.


Related in: MedlinePlus

A 42 years old man, chronic smoker and suffered acute coronary event. Note is made of premature graying of hair
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Figure 1: A 42 years old man, chronic smoker and suffered acute coronary event. Note is made of premature graying of hair

Mentions: The present study demonstrated that CIMT measurements and dyslipidemia were significantly different from the control group compared to smokers alone as well as with CAD. When the three groups were compared with respect to graying of hairs, it was found that graying present in the groups of smokers and CAD, was significantly higher than smokers alone as well as controls (Fig 1). It was also found that graying of hairs was independently related to risk of coronary artery disease.


Premature Graying of Hair: An Independent Risk Marker for Coronary Artery Disease in Smokers - A Retrospective Case Control Study.

Aggarwal A, Srivastava S, Agarwal MP, Dwivedi S - Ethiop J Health Sci (2015)

A 42 years old man, chronic smoker and suffered acute coronary event. Note is made of premature graying of hair
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4478263&req=5

Figure 1: A 42 years old man, chronic smoker and suffered acute coronary event. Note is made of premature graying of hair
Mentions: The present study demonstrated that CIMT measurements and dyslipidemia were significantly different from the control group compared to smokers alone as well as with CAD. When the three groups were compared with respect to graying of hairs, it was found that graying present in the groups of smokers and CAD, was significantly higher than smokers alone as well as controls (Fig 1). It was also found that graying of hairs was independently related to risk of coronary artery disease.

Bottom Line: All subjects were males.The carotid intima media thickness, dyslipidemia and blood pressure were significantly higher in group I and II as compared to group III.When the groups were compared for graying of hair, it was found that the group II (i.e., smokers and CAD) had maximum prevalence of graying which was significantly higher than the control as well as smoker groups.

View Article: PubMed Central - PubMed

Affiliation: Department of Medicine, University College of Medical Sciences & GTB Hospital, Delhi, India.

ABSTRACT

Background: Premature graying of hair as a risk marker among young smokers has a potential of identifying coronary artery disease (CAD) at a very early stage. There is absence of literature that assesses premature graying of hair as an independent marker of CAD in smokers.

Material and methods: The present single-centre case control study enrolled a total of 62 consecutive chronic smokers (≤ 45 years) (Group I) and 60 consecutive young CAD patients (≤45 years) who were chronic smokers (Group II). Another group comprising of 114 patients (≤45 years) having no smoking history and no cardiac ailments either (Group III) was enrolled as control population. All subjects were males. A detailed history and clinical examination regarding conventional coronary risk factors and carotid intima media thickness was done in both groups.

Results: The carotid intima media thickness, dyslipidemia and blood pressure were significantly higher in group I and II as compared to group III. When the groups were compared for graying of hair, it was found that the group II (i.e., smokers and CAD) had maximum prevalence of graying which was significantly higher than the control as well as smoker groups. The presence of premature graying of hair was associated with 3.24 times the risk of CAD on multiple logistic regression analysis.

Conclusion: The presence of premature graying of hair was associated with an increased risk of CAD in young smokers. Premature graying of hair can be used as preliminary evidence by clinicians for classifying patients at risk for premature CAD especially in smokers.

No MeSH data available.


Related in: MedlinePlus