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Pulmonary leukostasis with severe respiratory impairment as a debut of acute myeloid leukemia.

Rico-Rodríguez J, Villanueva-Ortiz Á, Santana-Cabrera L, Rodríguez-Pérez H - Int J Crit Illn Inj Sci (2015 Apr-Jun)

Bottom Line: We report the case of a woman, with severe respiratory impairment as a debut of acute myeloid leukemia who suspecting a pulmonary leukostasis, leukoapheresis was applied.

View Article: PubMed Central - PubMed

Affiliation: Department of Intensive Care, Universitary Hospital Insular of Gran Canaria, Las Palmas de Gran Canaria, Spain.

ABSTRACT
We report the case of a woman, with severe respiratory impairment as a debut of acute myeloid leukemia who suspecting a pulmonary leukostasis, leukoapheresis was applied.

No MeSH data available.


Related in: MedlinePlus

The chest x ray show an alveolar-interstitial infiltrate in the four quadrants with bibasal dominance (Figure a). After treatment showed an evident improvement of the infiltrates (Figure b)
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Figure 1: The chest x ray show an alveolar-interstitial infiltrate in the four quadrants with bibasal dominance (Figure a). After treatment showed an evident improvement of the infiltrates (Figure b)

Mentions: Blood tests showed leukostasis of 369000 u/L with 81% blasts, hemoglobin of 2g/dL, platelets 30000 u/L. The chest X-ray showed adifuse alveolar-interstitial infiltrate [Figure 1a]. By aspirate and bone marrow biopsy, diagnosis of acute myeloid leukemia MO (M0 through M7 are the subtypes of acute myeloid leukemia, based on the type of cell and M0 designates acute myeloid leukemia with minimal morphologic or cytochemical differentiation) of Franco American British (FAB) classification was confirmed. Suspecting a pulmonary leukostasis, leukoapheresis was initiated (technique by which blood from a vein is removed, leukocytes are removed selectively, and the remaining blood is reinfused into the donor) in two sessions, 6 hours apart, blood transfusion and chemotherapy, reducing the leukocyte count to 18000 u/L at the fourth day of admission improving in the respiratory function, allowing to remove mechanical ventilation 4 days after admission [Figure 1b].


Pulmonary leukostasis with severe respiratory impairment as a debut of acute myeloid leukemia.

Rico-Rodríguez J, Villanueva-Ortiz Á, Santana-Cabrera L, Rodríguez-Pérez H - Int J Crit Illn Inj Sci (2015 Apr-Jun)

The chest x ray show an alveolar-interstitial infiltrate in the four quadrants with bibasal dominance (Figure a). After treatment showed an evident improvement of the infiltrates (Figure b)
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4477392&req=5

Figure 1: The chest x ray show an alveolar-interstitial infiltrate in the four quadrants with bibasal dominance (Figure a). After treatment showed an evident improvement of the infiltrates (Figure b)
Mentions: Blood tests showed leukostasis of 369000 u/L with 81% blasts, hemoglobin of 2g/dL, platelets 30000 u/L. The chest X-ray showed adifuse alveolar-interstitial infiltrate [Figure 1a]. By aspirate and bone marrow biopsy, diagnosis of acute myeloid leukemia MO (M0 through M7 are the subtypes of acute myeloid leukemia, based on the type of cell and M0 designates acute myeloid leukemia with minimal morphologic or cytochemical differentiation) of Franco American British (FAB) classification was confirmed. Suspecting a pulmonary leukostasis, leukoapheresis was initiated (technique by which blood from a vein is removed, leukocytes are removed selectively, and the remaining blood is reinfused into the donor) in two sessions, 6 hours apart, blood transfusion and chemotherapy, reducing the leukocyte count to 18000 u/L at the fourth day of admission improving in the respiratory function, allowing to remove mechanical ventilation 4 days after admission [Figure 1b].

Bottom Line: We report the case of a woman, with severe respiratory impairment as a debut of acute myeloid leukemia who suspecting a pulmonary leukostasis, leukoapheresis was applied.

View Article: PubMed Central - PubMed

Affiliation: Department of Intensive Care, Universitary Hospital Insular of Gran Canaria, Las Palmas de Gran Canaria, Spain.

ABSTRACT
We report the case of a woman, with severe respiratory impairment as a debut of acute myeloid leukemia who suspecting a pulmonary leukostasis, leukoapheresis was applied.

No MeSH data available.


Related in: MedlinePlus