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The addition of high magnifying endoscopy improves rates of high confidence optical diagnosis of colorectal polyps.

Iwatate M, Sano Y, Hattori S, Sano W, Hasuike N, Ikumoto T, Kotaka M, Murakami Y, Hewett DG, Soetikno R, Kaltenbach T, Fujimori T - Endosc Int Open (2015)

Bottom Line: Consecutive adult patients undergoing colonoscopy with a high magnifying (maximum, × 80) colonoscope between April and August 2012 were recruited.A level of confidence was assigned to each prediction.UMIN 000007608.

View Article: PubMed Central - PubMed

Affiliation: Sano Hospital, Gastrointestinal Center, Kobe, Japan.

ABSTRACT

Background and study aims: The real-time optical diagnosis of colorectal polyps with high confidence predictions can achieve high levels of accuracy. Increasing the rates of high confidence optical diagnosis can improve the clinical application of real-time optical diagnosis in routine practice. The primary aim of this prospective study was to evaluate whether high magnifying endoscopy improves the rates of high confidence narrow-band imaging (NBI) - based optical diagnosis for differentiating between neoplastic and non-neoplastic colorectal lesions according to the NBI international colorectal endoscopic (NICE) classification.

Patients and methods: Consecutive adult patients undergoing colonoscopy with a high magnifying (maximum, × 80) colonoscope between April and August 2012 were recruited. The optical diagnosis for each polyp was evaluated during colonoscopy in two consecutive stages by the same endoscopist, who first used NBI with non-magnifying endoscopy (NBI-NME), then NBI with magnifying endoscopy (NBI-ME). A level of confidence was assigned to each prediction.

Results: The analysis included 124 patients (mean age, 56.4 years; male-to-female ratio, 72:52) with 248 polyps smaller than 10 mm. Of the 248 polyps, 210 were 1 to 5 mm in size and 38 were 6 to 9 mm in size; 77 polyps were hyperplastic, 4 were sessile serrated adenomas/polyps, 160 were low grade adenomas, 5 were high grade adenomas, and 2 were deep submucosal invasive carcinomas. The rate of high confidence optical diagnosis when NBI-ME was used was significantly higher than the rate when NBI-NME was used for diminutive (1 - 5 mm) polyps (92.9 % vs 79.5 %, P < 0.001) and for small (6 - 9 mm) polyps (94.7 % vs 84.2 %, P = 0.048).

Conclusion: High magnifying endoscopy significantly improved the rates of high confidence NBI-based optical diagnosis of diminutive and small colorectal polyps.

Study registration: UMIN 000007608.

No MeSH data available.


Related in: MedlinePlus

 Patient flow chart.
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FI131-3:  Patient flow chart.

Mentions: Of the 329 patients invited to participate, 124 patients with 248 polyps (< 10 mm) were analyzed prospectively (Fig. 3). All participants underwent total colonoscopy to the cecum. The SCs performed 44 colonoscopies and detected 85 polyps; the GEs performed 80 colonoscopies and detected 163 polyps. The polyp detection rates per procedure were 1.9 (85/44) for the SCs and 2.0 (163/80) for the GEs. There was no significant difference between the two groups.


The addition of high magnifying endoscopy improves rates of high confidence optical diagnosis of colorectal polyps.

Iwatate M, Sano Y, Hattori S, Sano W, Hasuike N, Ikumoto T, Kotaka M, Murakami Y, Hewett DG, Soetikno R, Kaltenbach T, Fujimori T - Endosc Int Open (2015)

 Patient flow chart.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4477263&req=5

FI131-3:  Patient flow chart.
Mentions: Of the 329 patients invited to participate, 124 patients with 248 polyps (< 10 mm) were analyzed prospectively (Fig. 3). All participants underwent total colonoscopy to the cecum. The SCs performed 44 colonoscopies and detected 85 polyps; the GEs performed 80 colonoscopies and detected 163 polyps. The polyp detection rates per procedure were 1.9 (85/44) for the SCs and 2.0 (163/80) for the GEs. There was no significant difference between the two groups.

Bottom Line: Consecutive adult patients undergoing colonoscopy with a high magnifying (maximum, × 80) colonoscope between April and August 2012 were recruited.A level of confidence was assigned to each prediction.UMIN 000007608.

View Article: PubMed Central - PubMed

Affiliation: Sano Hospital, Gastrointestinal Center, Kobe, Japan.

ABSTRACT

Background and study aims: The real-time optical diagnosis of colorectal polyps with high confidence predictions can achieve high levels of accuracy. Increasing the rates of high confidence optical diagnosis can improve the clinical application of real-time optical diagnosis in routine practice. The primary aim of this prospective study was to evaluate whether high magnifying endoscopy improves the rates of high confidence narrow-band imaging (NBI) - based optical diagnosis for differentiating between neoplastic and non-neoplastic colorectal lesions according to the NBI international colorectal endoscopic (NICE) classification.

Patients and methods: Consecutive adult patients undergoing colonoscopy with a high magnifying (maximum, × 80) colonoscope between April and August 2012 were recruited. The optical diagnosis for each polyp was evaluated during colonoscopy in two consecutive stages by the same endoscopist, who first used NBI with non-magnifying endoscopy (NBI-NME), then NBI with magnifying endoscopy (NBI-ME). A level of confidence was assigned to each prediction.

Results: The analysis included 124 patients (mean age, 56.4 years; male-to-female ratio, 72:52) with 248 polyps smaller than 10 mm. Of the 248 polyps, 210 were 1 to 5 mm in size and 38 were 6 to 9 mm in size; 77 polyps were hyperplastic, 4 were sessile serrated adenomas/polyps, 160 were low grade adenomas, 5 were high grade adenomas, and 2 were deep submucosal invasive carcinomas. The rate of high confidence optical diagnosis when NBI-ME was used was significantly higher than the rate when NBI-NME was used for diminutive (1 - 5 mm) polyps (92.9 % vs 79.5 %, P < 0.001) and for small (6 - 9 mm) polyps (94.7 % vs 84.2 %, P = 0.048).

Conclusion: High magnifying endoscopy significantly improved the rates of high confidence NBI-based optical diagnosis of diminutive and small colorectal polyps.

Study registration: UMIN 000007608.

No MeSH data available.


Related in: MedlinePlus