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Extranodal Rosai-Dorfman Disease Involving the Left Atrium: Cardiac MRI, CT, and PET Scan Findings.

Daruwalla VJ, Parekh K, Tahir H, Collins JD, Carr J - Case Rep Radiol (2015)

Bottom Line: Rosai-Dorfman disease (RDD) is a rare entity that usually involves the lymph nodes but extranodal involvements have been seen in numerous cases, although RDD with cardiovascular involvement is extremely rare.We describe a case of a young male who presented with intermittent palpitations and was found to have a left atrium mass.RDD should be considered as one of the differentials even for isolated cardiac lesions.

View Article: PubMed Central - PubMed

Affiliation: Conemaugh Memorial Hospital/Temple University, 1199 Mckinley Avenue, Johnstown, PA 15905, USA.

ABSTRACT
Rosai-Dorfman disease (RDD) is a rare entity that usually involves the lymph nodes but extranodal involvements have been seen in numerous cases, although RDD with cardiovascular involvement is extremely rare. We describe a case of a young male who presented with intermittent palpitations and was found to have a left atrium mass. Our case not only emphasizes the rarity of the above lesion but also highlights the importance of modern-day imaging like computed tomography, Cardiac Magnetic Resonance Imaging (CMRI), and PET scan in characterizing such nonspecific lesions and directing appropriate line of treatment. RDD should be considered as one of the differentials even for isolated cardiac lesions.

No MeSH data available.


Related in: MedlinePlus

PET scan. Avid uptake of Fluorodeoxyglucose (FDG) in region of mass is seen in left atrium (a). Uptake is also seen involving mediastinal nodes. Coronal image shows uptake in cardiac mass and mediastinal nodes (b). Focal area of uptake was noted near upper pole of left kidney (c).
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fig4: PET scan. Avid uptake of Fluorodeoxyglucose (FDG) in region of mass is seen in left atrium (a). Uptake is also seen involving mediastinal nodes. Coronal image shows uptake in cardiac mass and mediastinal nodes (b). Focal area of uptake was noted near upper pole of left kidney (c).

Mentions: 18F-fluorodeoxyglucose positron emission tomography has proven to be a valuable imaging technique for distinguishing neoplastic lesions from benign lesions and evaluating the extent and processes of the disease. It not only demonstrates the complete staging of the disease but also can provide functional information about the disease activity to guide biopsy. FDG PET imaging in our patient demonstrates foci of increased uptake in the mediastinum and right perihilar region, corresponding to soft tissue findings on the previous CT study (Figure 4). Focal area of uptake was noted near upper pole of left kidney, but, on further imaging by CT and MR of abdomen, no other definite lesion was identified. No other areas of uptake were noted on PET scan. PET scan is also a sensitive indicator for early prediction of treatment response in RDD.


Extranodal Rosai-Dorfman Disease Involving the Left Atrium: Cardiac MRI, CT, and PET Scan Findings.

Daruwalla VJ, Parekh K, Tahir H, Collins JD, Carr J - Case Rep Radiol (2015)

PET scan. Avid uptake of Fluorodeoxyglucose (FDG) in region of mass is seen in left atrium (a). Uptake is also seen involving mediastinal nodes. Coronal image shows uptake in cardiac mass and mediastinal nodes (b). Focal area of uptake was noted near upper pole of left kidney (c).
© Copyright Policy - open-access
Related In: Results  -  Collection

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getmorefigures.php?uid=PMC4477210&req=5

fig4: PET scan. Avid uptake of Fluorodeoxyglucose (FDG) in region of mass is seen in left atrium (a). Uptake is also seen involving mediastinal nodes. Coronal image shows uptake in cardiac mass and mediastinal nodes (b). Focal area of uptake was noted near upper pole of left kidney (c).
Mentions: 18F-fluorodeoxyglucose positron emission tomography has proven to be a valuable imaging technique for distinguishing neoplastic lesions from benign lesions and evaluating the extent and processes of the disease. It not only demonstrates the complete staging of the disease but also can provide functional information about the disease activity to guide biopsy. FDG PET imaging in our patient demonstrates foci of increased uptake in the mediastinum and right perihilar region, corresponding to soft tissue findings on the previous CT study (Figure 4). Focal area of uptake was noted near upper pole of left kidney, but, on further imaging by CT and MR of abdomen, no other definite lesion was identified. No other areas of uptake were noted on PET scan. PET scan is also a sensitive indicator for early prediction of treatment response in RDD.

Bottom Line: Rosai-Dorfman disease (RDD) is a rare entity that usually involves the lymph nodes but extranodal involvements have been seen in numerous cases, although RDD with cardiovascular involvement is extremely rare.We describe a case of a young male who presented with intermittent palpitations and was found to have a left atrium mass.RDD should be considered as one of the differentials even for isolated cardiac lesions.

View Article: PubMed Central - PubMed

Affiliation: Conemaugh Memorial Hospital/Temple University, 1199 Mckinley Avenue, Johnstown, PA 15905, USA.

ABSTRACT
Rosai-Dorfman disease (RDD) is a rare entity that usually involves the lymph nodes but extranodal involvements have been seen in numerous cases, although RDD with cardiovascular involvement is extremely rare. We describe a case of a young male who presented with intermittent palpitations and was found to have a left atrium mass. Our case not only emphasizes the rarity of the above lesion but also highlights the importance of modern-day imaging like computed tomography, Cardiac Magnetic Resonance Imaging (CMRI), and PET scan in characterizing such nonspecific lesions and directing appropriate line of treatment. RDD should be considered as one of the differentials even for isolated cardiac lesions.

No MeSH data available.


Related in: MedlinePlus