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Correlations between Phlegm Syndrome of Chinese Medicine and Coronary Angiography: A Systematic Review and Meta-Analysis.

Zhang QY, Liang H, Gong HW, Huang HY, Zhou XQ, Sun X - Evid Based Complement Alternat Med (2015)

Bottom Line: According to inclusion criteria, a total of 30 studies involving 5,055 CAD patients were included.We concluded that the coronary arteries lesions of CAD patients with phlegm syndrome were more severe than those with nonphlegm syndromes.Phlegm syndrome should, therefore, be regarded as a dangerous pattern of CAD with worse prognosis.

View Article: PubMed Central - PubMed

Affiliation: Hunan University of Chinese Medicine, Science-Education Industrial Park, Yuelu Region, Changsha 410208, China.

ABSTRACT
Phlegm is one of the most common patterns of coronary artery disease (CAD) in Chinese medicine. Our research was aimed at investigating the association between phlegm syndrome of CAD and coronary angiography (CAG) by meta-analysis. According to inclusion criteria, a total of 30 studies involving 5,055 CAD patients were included. The meta-analysis showed that phlegm syndrome patients were prone to multivessel disease (28 studies, OR = 1.53, 95% CI, 1.24 to 1.88, P < 0.01) and higher Gensini score (2 studies, OR = 5.90, 95% CI, 1.86 to 9.94, P = 0.004), but not obviously relevant to severe stenosis (≥75%) of coronary arteries (13 studies, OR = 1.20, 95% CI, 0.63 to 2.27, P = 0.57). We concluded that the coronary arteries lesions of CAD patients with phlegm syndrome were more severe than those with nonphlegm syndromes. Phlegm syndrome should, therefore, be regarded as a dangerous pattern of CAD with worse prognosis.

No MeSH data available.


Related in: MedlinePlus

Funnel plot for publication bias by association between phlegm syndrome and multivessel disease.
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Related In: Results  -  Collection


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fig6: Funnel plot for publication bias by association between phlegm syndrome and multivessel disease.

Mentions: No individual studies influencing the summary OR found by one-way sensitivity analysis, indicating that the pooled data was stable. There was no evidence of publication bias, because the funnel plot according to meta-analysis of association between phlegm syndrome and multivessel disease did not show obvious asymmetry by visual inspection (Figure 6), which was also confirmed by Egger's test (P = 0.527). However, some studies located out of the border, which may affect the result of the meta-analysis.


Correlations between Phlegm Syndrome of Chinese Medicine and Coronary Angiography: A Systematic Review and Meta-Analysis.

Zhang QY, Liang H, Gong HW, Huang HY, Zhou XQ, Sun X - Evid Based Complement Alternat Med (2015)

Funnel plot for publication bias by association between phlegm syndrome and multivessel disease.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4477186&req=5

fig6: Funnel plot for publication bias by association between phlegm syndrome and multivessel disease.
Mentions: No individual studies influencing the summary OR found by one-way sensitivity analysis, indicating that the pooled data was stable. There was no evidence of publication bias, because the funnel plot according to meta-analysis of association between phlegm syndrome and multivessel disease did not show obvious asymmetry by visual inspection (Figure 6), which was also confirmed by Egger's test (P = 0.527). However, some studies located out of the border, which may affect the result of the meta-analysis.

Bottom Line: According to inclusion criteria, a total of 30 studies involving 5,055 CAD patients were included.We concluded that the coronary arteries lesions of CAD patients with phlegm syndrome were more severe than those with nonphlegm syndromes.Phlegm syndrome should, therefore, be regarded as a dangerous pattern of CAD with worse prognosis.

View Article: PubMed Central - PubMed

Affiliation: Hunan University of Chinese Medicine, Science-Education Industrial Park, Yuelu Region, Changsha 410208, China.

ABSTRACT
Phlegm is one of the most common patterns of coronary artery disease (CAD) in Chinese medicine. Our research was aimed at investigating the association between phlegm syndrome of CAD and coronary angiography (CAG) by meta-analysis. According to inclusion criteria, a total of 30 studies involving 5,055 CAD patients were included. The meta-analysis showed that phlegm syndrome patients were prone to multivessel disease (28 studies, OR = 1.53, 95% CI, 1.24 to 1.88, P < 0.01) and higher Gensini score (2 studies, OR = 5.90, 95% CI, 1.86 to 9.94, P = 0.004), but not obviously relevant to severe stenosis (≥75%) of coronary arteries (13 studies, OR = 1.20, 95% CI, 0.63 to 2.27, P = 0.57). We concluded that the coronary arteries lesions of CAD patients with phlegm syndrome were more severe than those with nonphlegm syndromes. Phlegm syndrome should, therefore, be regarded as a dangerous pattern of CAD with worse prognosis.

No MeSH data available.


Related in: MedlinePlus