Limits...
Nitrogen Dioxide Sterilization in Low-Resource Environments: A Feasibility Study.

Shomali M, Opie D, Avasthi T, Trilling A - PLoS ONE (2015)

Bottom Line: Access to sterilization is a critical need for global healthcare, as it is one of the prerequisites for safe surgical care.If developed and deployed, NO2 sterilization technology will have the twin benefits of reducing healthcare acquired infections and limiting a major constraint for access to surgical care on a global scale.Additional benefits are achieved in reducing costs and biohazard waste generated by current health care initiatives that rely primarily on disposable kits, increasing the effectiveness and outreach of these initiatives.

View Article: PubMed Central - PubMed

Affiliation: Eniware LLC, Washington D.C., United States of America.

ABSTRACT
Access to sterilization is a critical need for global healthcare, as it is one of the prerequisites for safe surgical care. Lack of sterilization capability has driven up healthcare infection rates as well as limited access to healthcare, especially in low-resource environments. Sterilization technology has for the most part been static and none of the established sterilization methods has been so far successfully adapted for use in low-resource environments on a large scale. It is evident that healthcare facilities in low-resource settings require reliable, deployable, durable, affordable, easily operable sterilization equipment that can operate independently of scarce resources. Recently commercialized nitrogen dioxide (NO2) sterilization technology was analyzed and adapted into a form factor suitable for use in low-resource environments. Lab testing was conducted in microbiological testing facilities simulating low-resource environments and in accordance with the requirements of the international sterilization standard ANSI/AAMI/ISO 14937 to assess effectiveness of the device and process. The feasibility of a portable sterilizer based on nitrogen dioxide has been demonstrated, showing that sterilization of medical instruments can occur in a form factor suitable for use in low-resource environments. If developed and deployed, NO2 sterilization technology will have the twin benefits of reducing healthcare acquired infections and limiting a major constraint for access to surgical care on a global scale. Additional benefits are achieved in reducing costs and biohazard waste generated by current health care initiatives that rely primarily on disposable kits, increasing the effectiveness and outreach of these initiatives.

No MeSH data available.


Related in: MedlinePlus

The Portable Sterilizer with Consumables.The portable sterilizer consists of a lockable case, a cartridge of sterilant gas, and an absorbent scrubber. A chemical indicator confirms successful sterilization.
© Copyright Policy
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4476675&req=5

pone.0130043.g001: The Portable Sterilizer with Consumables.The portable sterilizer consists of a lockable case, a cartridge of sterilant gas, and an absorbent scrubber. A chemical indicator confirms successful sterilization.

Mentions: This portable sterilizer (Fig 1) consists of a lockable case made from polypropylene polymer, supplied with sterilizing gas in a miniature cartridge and a gas scrubber. In this form, the portable sterilizer is an easy to use, comprehensive system in which medical devices can be sterilized. The design of the case and the gas delivery module allow for operation without a power source. Instruments are exposed to the sterilant gas through passive diffusion once the gas is mechanically released from the cartridge into the case. Absorption of the gas to a level that is safe for human exposure also occurs passively through the scrubber medium. A battery-operated timer tracks the sterilization and absorption process, alerting the operator when the cycle is complete and the case can be opened. Electricity is not used for any step of the process. All of the testing reported here used this version of sterilizer.


Nitrogen Dioxide Sterilization in Low-Resource Environments: A Feasibility Study.

Shomali M, Opie D, Avasthi T, Trilling A - PLoS ONE (2015)

The Portable Sterilizer with Consumables.The portable sterilizer consists of a lockable case, a cartridge of sterilant gas, and an absorbent scrubber. A chemical indicator confirms successful sterilization.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4476675&req=5

pone.0130043.g001: The Portable Sterilizer with Consumables.The portable sterilizer consists of a lockable case, a cartridge of sterilant gas, and an absorbent scrubber. A chemical indicator confirms successful sterilization.
Mentions: This portable sterilizer (Fig 1) consists of a lockable case made from polypropylene polymer, supplied with sterilizing gas in a miniature cartridge and a gas scrubber. In this form, the portable sterilizer is an easy to use, comprehensive system in which medical devices can be sterilized. The design of the case and the gas delivery module allow for operation without a power source. Instruments are exposed to the sterilant gas through passive diffusion once the gas is mechanically released from the cartridge into the case. Absorption of the gas to a level that is safe for human exposure also occurs passively through the scrubber medium. A battery-operated timer tracks the sterilization and absorption process, alerting the operator when the cycle is complete and the case can be opened. Electricity is not used for any step of the process. All of the testing reported here used this version of sterilizer.

Bottom Line: Access to sterilization is a critical need for global healthcare, as it is one of the prerequisites for safe surgical care.If developed and deployed, NO2 sterilization technology will have the twin benefits of reducing healthcare acquired infections and limiting a major constraint for access to surgical care on a global scale.Additional benefits are achieved in reducing costs and biohazard waste generated by current health care initiatives that rely primarily on disposable kits, increasing the effectiveness and outreach of these initiatives.

View Article: PubMed Central - PubMed

Affiliation: Eniware LLC, Washington D.C., United States of America.

ABSTRACT
Access to sterilization is a critical need for global healthcare, as it is one of the prerequisites for safe surgical care. Lack of sterilization capability has driven up healthcare infection rates as well as limited access to healthcare, especially in low-resource environments. Sterilization technology has for the most part been static and none of the established sterilization methods has been so far successfully adapted for use in low-resource environments on a large scale. It is evident that healthcare facilities in low-resource settings require reliable, deployable, durable, affordable, easily operable sterilization equipment that can operate independently of scarce resources. Recently commercialized nitrogen dioxide (NO2) sterilization technology was analyzed and adapted into a form factor suitable for use in low-resource environments. Lab testing was conducted in microbiological testing facilities simulating low-resource environments and in accordance with the requirements of the international sterilization standard ANSI/AAMI/ISO 14937 to assess effectiveness of the device and process. The feasibility of a portable sterilizer based on nitrogen dioxide has been demonstrated, showing that sterilization of medical instruments can occur in a form factor suitable for use in low-resource environments. If developed and deployed, NO2 sterilization technology will have the twin benefits of reducing healthcare acquired infections and limiting a major constraint for access to surgical care on a global scale. Additional benefits are achieved in reducing costs and biohazard waste generated by current health care initiatives that rely primarily on disposable kits, increasing the effectiveness and outreach of these initiatives.

No MeSH data available.


Related in: MedlinePlus