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Macular Pigment Optical Density and Ocular Pulse Amplitude in Subjects with Different Axial Lengths and Refractive Errors.

Czepita M, Karczewicz D, Safranow K, Czepita D - Med. Sci. Monit. (2015)

Bottom Line: The obtained results were analyzed statistically using Statistica 10 software.P values of <0.05 were considered statistically significant.There were no significant correlations between IOP and SE or AL. (1) MPOD is not correlated with the OPA in subjects with different AL and RE; (2) OPA decreases with the rise of AL; (3) OPA decreases with the fall of the SE; and (4) OPA increases with the rise in IOP.

View Article: PubMed Central - PubMed

Affiliation: Department of Ophthalmology, Pomeranian Medical University, Szczecin, Poland.

ABSTRACT

Background: The purpose of our study was to: (1) investigate the macular pigment optical density (MPOD) and ocular pulse amplitude (OPA) in subjects with different axial lengths (AL) and refractive errors (RE); (2) determine if there is a correlation between MPOD and OPA; and (3) evaluate whether MPOD and OPA depend on intraocular pressure (IOP).

Material and methods: This study included 140 eyes of 70 subjects - 17 men and 53 women, aged 18 to 29 years (mean: 22.5 years; SD=2.8). Every examined person underwent a thorough eye examination including: visual acuity, anterior segment and fundus examination, keratometry, auto-refractometry, and MPOD, OPA, AL, and IOP measurements. The obtained results were analyzed statistically using Statistica 10 software. P values of <0.05 were considered statistically significant.

Results: The following refractive errors were selected: emmetropia (34 eyes), hyperopia (18 eyes), low myopia (60 eyes), medium myopia (19 eyes), and high myopia (9 eyes). It has been established that the OPA increases with the rise in the spherical equivalents (SE) (Rs=+0.38, P<0.001), while the increase in AL correlates with the decrease of OPA (Rs=-0.40, P<0.001). The increase in IOP correlates with the rise in the OPA (Rs=+0.20, P<0.05). There were no significant correlations between IOP and SE or AL.

Conclusions: (1) MPOD is not correlated with the OPA in subjects with different AL and RE; (2) OPA decreases with the rise of AL; (3) OPA decreases with the fall of the SE; and (4) OPA increases with the rise in IOP.

No MeSH data available.


Related in: MedlinePlus

Ocular pulse amplitude and spherical equivalent.
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f1-medscimonit-21-1716: Ocular pulse amplitude and spherical equivalent.

Mentions: It has been established that the OPA increases with the rise in the SE (Rs=+0.38, P<0.001) (Figure 1), while the increase in axial length correlates with the decrease of ocular pulse amplitude (Rs=–0.40, P<0.001) (Figure 2).


Macular Pigment Optical Density and Ocular Pulse Amplitude in Subjects with Different Axial Lengths and Refractive Errors.

Czepita M, Karczewicz D, Safranow K, Czepita D - Med. Sci. Monit. (2015)

Ocular pulse amplitude and spherical equivalent.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4471852&req=5

f1-medscimonit-21-1716: Ocular pulse amplitude and spherical equivalent.
Mentions: It has been established that the OPA increases with the rise in the SE (Rs=+0.38, P<0.001) (Figure 1), while the increase in axial length correlates with the decrease of ocular pulse amplitude (Rs=–0.40, P<0.001) (Figure 2).

Bottom Line: The obtained results were analyzed statistically using Statistica 10 software.P values of <0.05 were considered statistically significant.There were no significant correlations between IOP and SE or AL. (1) MPOD is not correlated with the OPA in subjects with different AL and RE; (2) OPA decreases with the rise of AL; (3) OPA decreases with the fall of the SE; and (4) OPA increases with the rise in IOP.

View Article: PubMed Central - PubMed

Affiliation: Department of Ophthalmology, Pomeranian Medical University, Szczecin, Poland.

ABSTRACT

Background: The purpose of our study was to: (1) investigate the macular pigment optical density (MPOD) and ocular pulse amplitude (OPA) in subjects with different axial lengths (AL) and refractive errors (RE); (2) determine if there is a correlation between MPOD and OPA; and (3) evaluate whether MPOD and OPA depend on intraocular pressure (IOP).

Material and methods: This study included 140 eyes of 70 subjects - 17 men and 53 women, aged 18 to 29 years (mean: 22.5 years; SD=2.8). Every examined person underwent a thorough eye examination including: visual acuity, anterior segment and fundus examination, keratometry, auto-refractometry, and MPOD, OPA, AL, and IOP measurements. The obtained results were analyzed statistically using Statistica 10 software. P values of <0.05 were considered statistically significant.

Results: The following refractive errors were selected: emmetropia (34 eyes), hyperopia (18 eyes), low myopia (60 eyes), medium myopia (19 eyes), and high myopia (9 eyes). It has been established that the OPA increases with the rise in the spherical equivalents (SE) (Rs=+0.38, P<0.001), while the increase in AL correlates with the decrease of OPA (Rs=-0.40, P<0.001). The increase in IOP correlates with the rise in the OPA (Rs=+0.20, P<0.05). There were no significant correlations between IOP and SE or AL.

Conclusions: (1) MPOD is not correlated with the OPA in subjects with different AL and RE; (2) OPA decreases with the rise of AL; (3) OPA decreases with the fall of the SE; and (4) OPA increases with the rise in IOP.

No MeSH data available.


Related in: MedlinePlus