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Arthroscopic surgery for degenerative knee: systematic review and meta-analysis of benefits and harms.

Thorlund JB, Juhl CB, Roos EM, Lohmander LS - BMJ (2015)

Bottom Line: No significant benefit on physical function was found (effect size 0.09, -0.05 to 0.24).Knee arthroscopy is associated with harms.PROSPERO CRD42014009145.

View Article: PubMed Central - PubMed

Affiliation: University of Southern Denmark, Department of Sports Science and Clinical Biomechanics, Campusvej 55, 5230 Odense M, Denmark jthorlund@health.sdu.dk.

No MeSH data available.


Related in: MedlinePlus

Fig 5 Evaluation of risk of bias in primary analysis of pain. P value indicates difference between studies dependent on risk of bias scoring (that is, adequate, inadequate, and unclear)
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fig5: Fig 5 Evaluation of risk of bias in primary analysis of pain. P value indicates difference between studies dependent on risk of bias scoring (that is, adequate, inadequate, and unclear)

Mentions: Analysis of the effect of risk of bias showed no differences between studies scored as adequate, unclear, or inadequate on any of the domains investigated (fig 5 and supplementary figure B). We also did subgroup analyses on the primary endpoint analysis of pain and physical function for the osteoarthritis status of the study population (ranging from no radiographic osteoarthritis at all via a mixed population to all having radiographic osteoarthritis) and for type of surgery (partial meniscectomy with or without concomitant debridement) (fig 6 and supplementary figure C). These analyses did not change the interpretation of the results from the primary analyses. Subgroup analysis stratified for presence/absence of mechanical symptoms was not possible owing to lack of data. In a further subgroup analysis to evaluate the influence of study design, we found no differences between studies with different control interventions (fig 6 and supplementary figure C).


Arthroscopic surgery for degenerative knee: systematic review and meta-analysis of benefits and harms.

Thorlund JB, Juhl CB, Roos EM, Lohmander LS - BMJ (2015)

Fig 5 Evaluation of risk of bias in primary analysis of pain. P value indicates difference between studies dependent on risk of bias scoring (that is, adequate, inadequate, and unclear)
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4469973&req=5

fig5: Fig 5 Evaluation of risk of bias in primary analysis of pain. P value indicates difference between studies dependent on risk of bias scoring (that is, adequate, inadequate, and unclear)
Mentions: Analysis of the effect of risk of bias showed no differences between studies scored as adequate, unclear, or inadequate on any of the domains investigated (fig 5 and supplementary figure B). We also did subgroup analyses on the primary endpoint analysis of pain and physical function for the osteoarthritis status of the study population (ranging from no radiographic osteoarthritis at all via a mixed population to all having radiographic osteoarthritis) and for type of surgery (partial meniscectomy with or without concomitant debridement) (fig 6 and supplementary figure C). These analyses did not change the interpretation of the results from the primary analyses. Subgroup analysis stratified for presence/absence of mechanical symptoms was not possible owing to lack of data. In a further subgroup analysis to evaluate the influence of study design, we found no differences between studies with different control interventions (fig 6 and supplementary figure C).

Bottom Line: No significant benefit on physical function was found (effect size 0.09, -0.05 to 0.24).Knee arthroscopy is associated with harms.PROSPERO CRD42014009145.

View Article: PubMed Central - PubMed

Affiliation: University of Southern Denmark, Department of Sports Science and Clinical Biomechanics, Campusvej 55, 5230 Odense M, Denmark jthorlund@health.sdu.dk.

No MeSH data available.


Related in: MedlinePlus