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Hypnosis-based psychodynamic treatment in ALS: a longitudinal study on patients and their caregivers.

Kleinbub JR, Palmieri A, Broggio A, Pagnini F, Benelli E, Sambin M, Sorarù G - Front Psychol (2015)

Bottom Line: The observed massive use of primitive defense mechanisms was found to have a reliable and constant buffer effect on psychopathological symptoms in both patients and caregivers.Our brief psychodynamic hypnosis-based treatment showed efficacy both at psychological and physical levels in patients with ALS, and was indirectly associated to long-lasting benefits in caregivers.Future directions should be oriented toward a convergence of our results and further psychological interventions, in order to delineate clinical best practices for ALS.

View Article: PubMed Central - PubMed

Affiliation: Department of Philosophy, Sociology, Pedagogy and Applied Psychology, University of Padova Padova, Italy.

ABSTRACT

Background: Evidence of psychological treatment efficacy is strongly needed in ALS, particularly regarding long-term effects.

Methods: Fifteen patients participated in a hypnosis treatment and self-hypnosis training protocol after an in-depth psychological and neurological evaluation. Patients' primary caregivers and 15 one-by-one matched control patients were considered in the study. Measurements of anxiety, depression and quality of life (QoL) were collected at the baseline, post-treatment, and after 3 and 6 months from the intervention. Bayesian linear mixed-models were used to evaluate the impact of treatment and defense style on patients' anxiety, depression, QoL, and functional impairment (ALSFRS-r), as well as on caregivers' anxiety and depression.

Results: The statistical analyses revealed an improvement in psychological variables' scores immediately after the treatment. Amelioration in patients' and caregivers' anxiety as well as caregivers' depression, were found to persist at 3 and 6 months follow-ups. The observed massive use of primitive defense mechanisms was found to have a reliable and constant buffer effect on psychopathological symptoms in both patients and caregivers. Notably, treated patients decline in ALSFRS-r score was observed to be slower than that of control group's patients.

Discussion: Our brief psychodynamic hypnosis-based treatment showed efficacy both at psychological and physical levels in patients with ALS, and was indirectly associated to long-lasting benefits in caregivers. The implications of peculiar psychodynamic factors and mind-body techniques are discussed. Future directions should be oriented toward a convergence of our results and further psychological interventions, in order to delineate clinical best practices for ALS.

No MeSH data available.


Related in: MedlinePlus

Bayes Factors of the chosen model for depression in caregivers and its simpler nested models against the  model. The bars, on logarithmic scale, represents the ratio of evidence between the different models. Thus, by visual comparison, the weight of each single factor can be inferred.
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Figure 9: Bayes Factors of the chosen model for depression in caregivers and its simpler nested models against the model. The bars, on logarithmic scale, represents the ratio of evidence between the different models. Thus, by visual comparison, the weight of each single factor can be inferred.

Mentions: The best model selected through the Bayesian linear regression showed an effect of the DSQ maladaptive score and of the treatment (Time factor) on caregivers' depression, but no interaction factors. The model shows an overall good fit (BF against “Id only” model > 1000, R2 = 0.79, RSE = 1.90, model parameters are reported in Table 6), additional BF are reported in Figure 9.


Hypnosis-based psychodynamic treatment in ALS: a longitudinal study on patients and their caregivers.

Kleinbub JR, Palmieri A, Broggio A, Pagnini F, Benelli E, Sambin M, Sorarù G - Front Psychol (2015)

Bayes Factors of the chosen model for depression in caregivers and its simpler nested models against the  model. The bars, on logarithmic scale, represents the ratio of evidence between the different models. Thus, by visual comparison, the weight of each single factor can be inferred.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4469765&req=5

Figure 9: Bayes Factors of the chosen model for depression in caregivers and its simpler nested models against the model. The bars, on logarithmic scale, represents the ratio of evidence between the different models. Thus, by visual comparison, the weight of each single factor can be inferred.
Mentions: The best model selected through the Bayesian linear regression showed an effect of the DSQ maladaptive score and of the treatment (Time factor) on caregivers' depression, but no interaction factors. The model shows an overall good fit (BF against “Id only” model > 1000, R2 = 0.79, RSE = 1.90, model parameters are reported in Table 6), additional BF are reported in Figure 9.

Bottom Line: The observed massive use of primitive defense mechanisms was found to have a reliable and constant buffer effect on psychopathological symptoms in both patients and caregivers.Our brief psychodynamic hypnosis-based treatment showed efficacy both at psychological and physical levels in patients with ALS, and was indirectly associated to long-lasting benefits in caregivers.Future directions should be oriented toward a convergence of our results and further psychological interventions, in order to delineate clinical best practices for ALS.

View Article: PubMed Central - PubMed

Affiliation: Department of Philosophy, Sociology, Pedagogy and Applied Psychology, University of Padova Padova, Italy.

ABSTRACT

Background: Evidence of psychological treatment efficacy is strongly needed in ALS, particularly regarding long-term effects.

Methods: Fifteen patients participated in a hypnosis treatment and self-hypnosis training protocol after an in-depth psychological and neurological evaluation. Patients' primary caregivers and 15 one-by-one matched control patients were considered in the study. Measurements of anxiety, depression and quality of life (QoL) were collected at the baseline, post-treatment, and after 3 and 6 months from the intervention. Bayesian linear mixed-models were used to evaluate the impact of treatment and defense style on patients' anxiety, depression, QoL, and functional impairment (ALSFRS-r), as well as on caregivers' anxiety and depression.

Results: The statistical analyses revealed an improvement in psychological variables' scores immediately after the treatment. Amelioration in patients' and caregivers' anxiety as well as caregivers' depression, were found to persist at 3 and 6 months follow-ups. The observed massive use of primitive defense mechanisms was found to have a reliable and constant buffer effect on psychopathological symptoms in both patients and caregivers. Notably, treated patients decline in ALSFRS-r score was observed to be slower than that of control group's patients.

Discussion: Our brief psychodynamic hypnosis-based treatment showed efficacy both at psychological and physical levels in patients with ALS, and was indirectly associated to long-lasting benefits in caregivers. The implications of peculiar psychodynamic factors and mind-body techniques are discussed. Future directions should be oriented toward a convergence of our results and further psychological interventions, in order to delineate clinical best practices for ALS.

No MeSH data available.


Related in: MedlinePlus