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Taenia solium taeniosis/cysticercosis and the co-distribution with schistosomiasis in Africa.

Braae UC, Saarnak CF, Mukaratirwa S, Devleesschauwer B, Magnussen P, Johansen MV - Parasit Vectors (2015)

Bottom Line: Presence of both parasites was confirmed in 124 districts in 17 countries.With the paucity of data, T. solium infection is grossly under-reported and expected to be more widespread than this study suggests.In areas where co-distribution occurs there is a need for increased emphasis on evaluation of integrated intervention approaches for these two helminth infections and allocation of resources for evaluating the extent of adverse effects caused by mass drug administration.

View Article: PubMed Central - PubMed

Affiliation: Department of Veterinary Disease Biology, Section for Parasitology and Aquatic Diseases, Faculty of Health and Medical Sciences, University of Copenhagen, DK-1870, Frederiksberg, Denmark. braae@sund.ku.dk.

ABSTRACT

Background: This study aimed to map the distribution of Taenia solium taeniosis/cysticercosis and the co-distribution with schistosomiasis in Africa. These two major neglected tropical diseases are presumed to be widely distributed in Africa, but currently the level of co-distribution is unclear.

Methods: A literature search on T. solium taeniosis/cysticercosis was performed to compile all known studies on the presence of T. solium and apparent prevalence of taeniosis and porcine cysticercosis in Africa. Studies were geo-referenced using an online gazetteer. A Bayesian framework was used to combine the epidemiological data on the apparent prevalence with external information on test characteristics to estimate informed district-level prevalence of taeniosis and porcine cysticercosis. Districts with T. solium taeniosis/cysticercosis presence were cross-referenced with the Global Neglected Tropical Diseases Database for schistosomiasis presence.

Results: The search strategies identified 141 reports of T. solium in Africa from 1985 to 2014 from a total of 476 districts in 29 countries, 20 with porcine cysticercosis, 22 with human cysticercosis, and 16 with taeniosis, in addition to 2 countries identified from OIE reports. All 31 countries were considered, on national scale, to have co-distribution with schistosomiasis. Presence of both parasites was confirmed in 124 districts in 17 countries. The informed prevalence of taeniosis and porcine cysticercosis were estimated for 14 and 41 districts in 10 and 13 countries, respectively.

Conclusions: With the paucity of data, T. solium infection is grossly under-reported and expected to be more widespread than this study suggests. In areas where co-distribution occurs there is a need for increased emphasis on evaluation of integrated intervention approaches for these two helminth infections and allocation of resources for evaluating the extent of adverse effects caused by mass drug administration.

No MeSH data available.


Related in: MedlinePlus

Informed prevalence of taeniosis in Africa from 1983 to 2010
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Fig6: Informed prevalence of taeniosis in Africa from 1983 to 2010

Mentions: Figures 6 and 7 represent the informed prevalence estimated for T. solium taeniosis and porcine cysticercosis, respectively, based on the studies that fulfilled the criteria for Bayesian inference (Table 3), and the selection criteria. Informed prevalence for taeniosis was calculated for 14 districts in 10 countries out of the 16 countries in which taeniosis were found (Fig. 6). For Côte d’Ivoire, Madagascar, Mozambique, Namibia, Togo, and Zimbabwe the literature did not contain the necessary epidemiological information and was excluded from the analysis. Informed prevalence for porcine cysticercosis was estimated for 41 districts in 13 out of the 20 countries in which porcine cysticercosis were confirmed (Fig. 7). Finally, detailed epidemiological data on porcine cysticercosis infection were missing from 7 (65 %) out of the 20 endemic countries based on the literature.Fig. 6


Taenia solium taeniosis/cysticercosis and the co-distribution with schistosomiasis in Africa.

Braae UC, Saarnak CF, Mukaratirwa S, Devleesschauwer B, Magnussen P, Johansen MV - Parasit Vectors (2015)

Informed prevalence of taeniosis in Africa from 1983 to 2010
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC4465723&req=5

Fig6: Informed prevalence of taeniosis in Africa from 1983 to 2010
Mentions: Figures 6 and 7 represent the informed prevalence estimated for T. solium taeniosis and porcine cysticercosis, respectively, based on the studies that fulfilled the criteria for Bayesian inference (Table 3), and the selection criteria. Informed prevalence for taeniosis was calculated for 14 districts in 10 countries out of the 16 countries in which taeniosis were found (Fig. 6). For Côte d’Ivoire, Madagascar, Mozambique, Namibia, Togo, and Zimbabwe the literature did not contain the necessary epidemiological information and was excluded from the analysis. Informed prevalence for porcine cysticercosis was estimated for 41 districts in 13 out of the 20 countries in which porcine cysticercosis were confirmed (Fig. 7). Finally, detailed epidemiological data on porcine cysticercosis infection were missing from 7 (65 %) out of the 20 endemic countries based on the literature.Fig. 6

Bottom Line: Presence of both parasites was confirmed in 124 districts in 17 countries.With the paucity of data, T. solium infection is grossly under-reported and expected to be more widespread than this study suggests.In areas where co-distribution occurs there is a need for increased emphasis on evaluation of integrated intervention approaches for these two helminth infections and allocation of resources for evaluating the extent of adverse effects caused by mass drug administration.

View Article: PubMed Central - PubMed

Affiliation: Department of Veterinary Disease Biology, Section for Parasitology and Aquatic Diseases, Faculty of Health and Medical Sciences, University of Copenhagen, DK-1870, Frederiksberg, Denmark. braae@sund.ku.dk.

ABSTRACT

Background: This study aimed to map the distribution of Taenia solium taeniosis/cysticercosis and the co-distribution with schistosomiasis in Africa. These two major neglected tropical diseases are presumed to be widely distributed in Africa, but currently the level of co-distribution is unclear.

Methods: A literature search on T. solium taeniosis/cysticercosis was performed to compile all known studies on the presence of T. solium and apparent prevalence of taeniosis and porcine cysticercosis in Africa. Studies were geo-referenced using an online gazetteer. A Bayesian framework was used to combine the epidemiological data on the apparent prevalence with external information on test characteristics to estimate informed district-level prevalence of taeniosis and porcine cysticercosis. Districts with T. solium taeniosis/cysticercosis presence were cross-referenced with the Global Neglected Tropical Diseases Database for schistosomiasis presence.

Results: The search strategies identified 141 reports of T. solium in Africa from 1985 to 2014 from a total of 476 districts in 29 countries, 20 with porcine cysticercosis, 22 with human cysticercosis, and 16 with taeniosis, in addition to 2 countries identified from OIE reports. All 31 countries were considered, on national scale, to have co-distribution with schistosomiasis. Presence of both parasites was confirmed in 124 districts in 17 countries. The informed prevalence of taeniosis and porcine cysticercosis were estimated for 14 and 41 districts in 10 and 13 countries, respectively.

Conclusions: With the paucity of data, T. solium infection is grossly under-reported and expected to be more widespread than this study suggests. In areas where co-distribution occurs there is a need for increased emphasis on evaluation of integrated intervention approaches for these two helminth infections and allocation of resources for evaluating the extent of adverse effects caused by mass drug administration.

No MeSH data available.


Related in: MedlinePlus