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Qualitative, semi-quantitative, and quantitative simulation of the osmoregulation system in yeast.

Pang W, Coghill GM - BioSystems (2015)

Bottom Line: This model was then simulated qualitatively, semi-quantitatively, and quantitatively.The obtained simulation results are presented with an analysis.Finally the future development of the Morven framework for modelling the dynamic biological systems is discussed.

View Article: PubMed Central - PubMed

Affiliation: School of Natural and Computing Sciences, University of Aberdeen, Aberdeen AB24 3UE, UK. Electronic address: pang.wei@abdn.ac.uk.

No MeSH data available.


The envisionment graph containing variables V and Gly.
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fig0020: The envisionment graph containing variables V and Gly.

Mentions: We first perform the total envisionment which only includes variables V and Gly because these two variables are easier to measure than others. Considering that each variable can take three possible values: 〈positive, zero〉, 〈positive, negative〉, and 〈positive, positive〉, there are 9 possible states. The obtained envisionment graph shown in Fig. 4 contains all these 9 states, which are listed in Table 7. The obtained results clearly shows that qualitative simulation can be performed on a model converted from an existing quantitative model. To obtain more precise prediction, more variables can be included and additional conditions can be specified.


Qualitative, semi-quantitative, and quantitative simulation of the osmoregulation system in yeast.

Pang W, Coghill GM - BioSystems (2015)

The envisionment graph containing variables V and Gly.
© Copyright Policy - CC BY
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4441110&req=5

fig0020: The envisionment graph containing variables V and Gly.
Mentions: We first perform the total envisionment which only includes variables V and Gly because these two variables are easier to measure than others. Considering that each variable can take three possible values: 〈positive, zero〉, 〈positive, negative〉, and 〈positive, positive〉, there are 9 possible states. The obtained envisionment graph shown in Fig. 4 contains all these 9 states, which are listed in Table 7. The obtained results clearly shows that qualitative simulation can be performed on a model converted from an existing quantitative model. To obtain more precise prediction, more variables can be included and additional conditions can be specified.

Bottom Line: This model was then simulated qualitatively, semi-quantitatively, and quantitatively.The obtained simulation results are presented with an analysis.Finally the future development of the Morven framework for modelling the dynamic biological systems is discussed.

View Article: PubMed Central - PubMed

Affiliation: School of Natural and Computing Sciences, University of Aberdeen, Aberdeen AB24 3UE, UK. Electronic address: pang.wei@abdn.ac.uk.

No MeSH data available.