Limits...
Pathology-MRI Correlation of Hepatocarcinogenesis: Recent Update.

Huh J, Kim KW, Kim J, Yu E - J Pathol Transl Med (2015)

Bottom Line: Understanding the important alterations during hepatocarcinogenesis as well as the characteristic magnetic resonance imaging (MRI) and histopathological features will be helpful for managing patients with chronic liver disease and hepatocellular carcinoma.Recent advances in MRI techniques, such as fat/iron quantification, diffusion-weighted images, and gadoxetic acid-enhanced MRI, have greatly enhanced our understanding of hepatocarcinogenesis.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

ABSTRACT
Understanding the important alterations during hepatocarcinogenesis as well as the characteristic magnetic resonance imaging (MRI) and histopathological features will be helpful for managing patients with chronic liver disease and hepatocellular carcinoma. Recent advances in MRI techniques, such as fat/iron quantification, diffusion-weighted images, and gadoxetic acid-enhanced MRI, have greatly enhanced our understanding of hepatocarcinogenesis.

No MeSH data available.


Related in: MedlinePlus

Tumor capsule of the hepatocellular carcinoma (HCC). The tumor capsule (arrowheads) is seen as a hypointense rim on the arterial-phase (AP) image (left) and as an enhancing rim on the portal-venous phase (PVP) image (middle), indicating a delayed and persistent enhancement pattern. On T2-weighted imaging (T2-WI), the tumor capsule is seen as a hyperintense rim (right).
© Copyright Policy
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4440933&req=5

f5-jptm-49-3-218: Tumor capsule of the hepatocellular carcinoma (HCC). The tumor capsule (arrowheads) is seen as a hypointense rim on the arterial-phase (AP) image (left) and as an enhancing rim on the portal-venous phase (PVP) image (middle), indicating a delayed and persistent enhancement pattern. On T2-weighted imaging (T2-WI), the tumor capsule is seen as a hyperintense rim (right).

Mentions: Thirdly, the tumor capsule is a characteristic feature of progressed HCCs [39]. It is usually seen as a thin rim of low SI on noncontrast T1-WI. On contrast-enhanced MRI, the tumor capsule can be progressively enhanced following injection of gadolinium contrast agent, as the tumor capsule is generally composed of fibrous tissue containing compressed vessels (Fig. 5) [12]. On T2-WI, the tumor capsule may show variable SI as either low SI or high SI. Although the tumor capsule is regarded as a characteristic finding of progressed HCCs, it may be present in large DNs and may not be seen in small HCCs. For the diagnosis of HCC, the presence of a tumor capsule is helpful, although not essential.


Pathology-MRI Correlation of Hepatocarcinogenesis: Recent Update.

Huh J, Kim KW, Kim J, Yu E - J Pathol Transl Med (2015)

Tumor capsule of the hepatocellular carcinoma (HCC). The tumor capsule (arrowheads) is seen as a hypointense rim on the arterial-phase (AP) image (left) and as an enhancing rim on the portal-venous phase (PVP) image (middle), indicating a delayed and persistent enhancement pattern. On T2-weighted imaging (T2-WI), the tumor capsule is seen as a hyperintense rim (right).
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4440933&req=5

f5-jptm-49-3-218: Tumor capsule of the hepatocellular carcinoma (HCC). The tumor capsule (arrowheads) is seen as a hypointense rim on the arterial-phase (AP) image (left) and as an enhancing rim on the portal-venous phase (PVP) image (middle), indicating a delayed and persistent enhancement pattern. On T2-weighted imaging (T2-WI), the tumor capsule is seen as a hyperintense rim (right).
Mentions: Thirdly, the tumor capsule is a characteristic feature of progressed HCCs [39]. It is usually seen as a thin rim of low SI on noncontrast T1-WI. On contrast-enhanced MRI, the tumor capsule can be progressively enhanced following injection of gadolinium contrast agent, as the tumor capsule is generally composed of fibrous tissue containing compressed vessels (Fig. 5) [12]. On T2-WI, the tumor capsule may show variable SI as either low SI or high SI. Although the tumor capsule is regarded as a characteristic finding of progressed HCCs, it may be present in large DNs and may not be seen in small HCCs. For the diagnosis of HCC, the presence of a tumor capsule is helpful, although not essential.

Bottom Line: Understanding the important alterations during hepatocarcinogenesis as well as the characteristic magnetic resonance imaging (MRI) and histopathological features will be helpful for managing patients with chronic liver disease and hepatocellular carcinoma.Recent advances in MRI techniques, such as fat/iron quantification, diffusion-weighted images, and gadoxetic acid-enhanced MRI, have greatly enhanced our understanding of hepatocarcinogenesis.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

ABSTRACT
Understanding the important alterations during hepatocarcinogenesis as well as the characteristic magnetic resonance imaging (MRI) and histopathological features will be helpful for managing patients with chronic liver disease and hepatocellular carcinoma. Recent advances in MRI techniques, such as fat/iron quantification, diffusion-weighted images, and gadoxetic acid-enhanced MRI, have greatly enhanced our understanding of hepatocarcinogenesis.

No MeSH data available.


Related in: MedlinePlus