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Renal replacement therapy in Europe: a summary of the 2012 ERA-EDTA Registry Annual Report.

Pippias M, Stel VS, Abad Diez JM, Afentakis N, Herrero-Calvo JA, Arias M, Tomilina N, Bouzas Caamaño E, Buturovic-Ponikvar J, Čala S, Caskey FJ, Castro de la Nuez P, Cernevskis H, Collart F, Alonso de la Torre R, García Bazaga Mde L, De Meester J, Díaz JM, Djukanovic L, Ferrer Alamar M, Finne P, Garneata L, Golan E, González Fernández R, Gutiérrez Avila G, Heaf J, Hoitsma A, Kantaria N, Kolesnyk M, Kramar R, Kramer A, Lassalle M, Leivestad T, Lopot F, Macário F, Magaz A, Martín-Escobar E, Metcalfe W, Noordzij M, Palsson R, Pechter Ü, Prütz KG, Ratkovic M, Resić H, Rutkowski B, Santiuste de Pablos C, Spustová V, Süleymanlar G, Van Stralen K, Thereska N, Wanner C, Jager KJ - Clin Kidney J (2015)

Bottom Line: The proportion of prevalent patients ≥75 years varied from 11 to 32% between countries.The overall renal transplantation rate in 2012 was 28.3 pmp (n = 15 673), with the highest rate seen in the Spanish region of Catalonia.Five-year adjusted survival for all RRT patients was 59.7% (95% confidence interval, CI: 59.3-60.0) which fell to 39.3% (95% CI: 38.7-39.9) in patients 65-74 years and 21.3% (95% CI: 20.8-21.9) in patients ≥75 years.

View Article: PubMed Central - PubMed

Affiliation: ERA-EDTA Registry, Department of Medical Informatics, Academic Medical Center, Universiteit van Amsterdam , Amsterdam , the Netherlands.

ABSTRACT

Background: This article summarizes the 2012 European Renal Association-European Dialysis and Transplant Association Registry Annual Report (available at www.era-edta-reg.org) with a specific focus on older patients (defined as ≥65 years).

Methods: Data provided by 45 national or regional renal registries in 30 countries in Europe and bordering the Mediterranean Sea were used. Individual patient level data were received from 31 renal registries, whereas 14 renal registries contributed data in an aggregated form. The incidence, prevalence and survival probabilities of patients with end-stage renal disease (ESRD) receiving renal replacement therapy (RRT) and renal transplantation rates for 2012 are presented.

Results: In 2012, the overall unadjusted incidence rate of patients with ESRD receiving RRT was 109.6 per million population (pmp) (n = 69 035), ranging from 219.9 pmp in Portugal to 24.2 pmp in Montenegro. The proportion of incident patients ≥75 years varied from 15 to 44% between countries. The overall unadjusted prevalence on 31 December 2012 was 716.7 pmp (n = 451 270), ranging from 1670.2 pmp in Portugal to 146.7 pmp in the Ukraine. The proportion of prevalent patients ≥75 years varied from 11 to 32% between countries. The overall renal transplantation rate in 2012 was 28.3 pmp (n = 15 673), with the highest rate seen in the Spanish region of Catalonia. The proportion of patients ≥65 years receiving a transplant ranged from 0 to 35%. Five-year adjusted survival for all RRT patients was 59.7% (95% confidence interval, CI: 59.3-60.0) which fell to 39.3% (95% CI: 38.7-39.9) in patients 65-74 years and 21.3% (95% CI: 20.8-21.9) in patients ≥75 years.

No MeSH data available.


Related in: MedlinePlus

Incidence of RRT, pmp at Day 1 in 2012, unadjusted (black bars) and standardized to the age and gender distribution of the EU27 population in 2010 (grey bars) and the mean and median age (years) at the start of RRT. Data are from renal registries providing individual level patient data (left panel) and from renal registries providing aggregated data (right panel). The incidence data for the Czech Republic and Slovakia only include dialysis patients. The mean and median age for Slovakia is based on dialysis patients and for Turkey only on haemodialysis patients. Dutch- and French-speaking Belgium, the Spanish regions of Cantabria, Castile and León and Castile-La Mancha and the UK; England, Northern Ireland and Wales do not report on patients younger than 20 years.
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SFV014F2: Incidence of RRT, pmp at Day 1 in 2012, unadjusted (black bars) and standardized to the age and gender distribution of the EU27 population in 2010 (grey bars) and the mean and median age (years) at the start of RRT. Data are from renal registries providing individual level patient data (left panel) and from renal registries providing aggregated data (right panel). The incidence data for the Czech Republic and Slovakia only include dialysis patients. The mean and median age for Slovakia is based on dialysis patients and for Turkey only on haemodialysis patients. Dutch- and French-speaking Belgium, the Spanish regions of Cantabria, Castile and León and Castile-La Mancha and the UK; England, Northern Ireland and Wales do not report on patients younger than 20 years.

Mentions: In 2012, the total number of patients starting RRT for ESRD among all the registries reporting to the ERA-EDTA Registry was 69 035. These registries covered a total population of 629.7 million, resulting in an unadjusted incidence rate of 109.6 per million population (pmp). Figure 1A and Figure 2 show the incidence of ESRD patients receiving RRT per pmp on Day 1, among all national and regional renal registries in 30 countries reporting to the ERA-EDTA Registry in 2012. The highest unadjusted incidence rates were reported in Portugal (219.9 pmp), Greece (209.7 pmp) and Georgia (199.6 pmp), whereas the lowest unadjusted incidence rates were reported in Montenegro (24.2 pmp), Ukraine (27.6 pmp) and Russia (48.1 pmp). The incidence rate standardized for the EU27 population was highest in Israel (280.5 pmp), Georgia (227.5 pmp) and French-speaking Belgium (201.1 pmp). The mean age at the start of RRT across Europe was 62.0 years in the renal registries providing individual level patient data and 58.2 years in the renal registries providing aggregated data (Figure 2). Figure 1B and Figure 3 provide information on the incidence of RRT, per million age-related population (pmarp), on Day 1 for older patients. For the countries providing individual level data; the incidence of RRT for patients aged 65–74 years or 75 years and over varied considerably between the renal registries (Figure 3). The lowest incidence rate of patients aged 65–74 and 75 years and over was reported in Finland (199.8 and 220.8 pmarp, respectively). A more than three times as high incidence rate was reported in French-speaking Belgium (619.4 pmarp) for patients aged 65–74 years and Dutch-speaking Belgium (893.6 pmarp) for patients aged over 75 years (Figure 3). Within each country or region, there was a wide variation in the proportion of ESRD patients aged 75 years and over commencing RRT with the highest proportion reported in Dutch-speaking Belgium (44%) and Greece (43%) and the lowest proportion in Romania (15%) and Serbia (15%). Within the countries supplying individual level data, the four national or regional registries with the highest adjusted incidence of RRT on Day 1 (Greece, French- and Dutch-speaking Belgium and France) also had the highest incidence of RRT on Day 1 for patients 75 years and over (Figure 1A–B and 3).Fig. 2.


Renal replacement therapy in Europe: a summary of the 2012 ERA-EDTA Registry Annual Report.

Pippias M, Stel VS, Abad Diez JM, Afentakis N, Herrero-Calvo JA, Arias M, Tomilina N, Bouzas Caamaño E, Buturovic-Ponikvar J, Čala S, Caskey FJ, Castro de la Nuez P, Cernevskis H, Collart F, Alonso de la Torre R, García Bazaga Mde L, De Meester J, Díaz JM, Djukanovic L, Ferrer Alamar M, Finne P, Garneata L, Golan E, González Fernández R, Gutiérrez Avila G, Heaf J, Hoitsma A, Kantaria N, Kolesnyk M, Kramar R, Kramer A, Lassalle M, Leivestad T, Lopot F, Macário F, Magaz A, Martín-Escobar E, Metcalfe W, Noordzij M, Palsson R, Pechter Ü, Prütz KG, Ratkovic M, Resić H, Rutkowski B, Santiuste de Pablos C, Spustová V, Süleymanlar G, Van Stralen K, Thereska N, Wanner C, Jager KJ - Clin Kidney J (2015)

Incidence of RRT, pmp at Day 1 in 2012, unadjusted (black bars) and standardized to the age and gender distribution of the EU27 population in 2010 (grey bars) and the mean and median age (years) at the start of RRT. Data are from renal registries providing individual level patient data (left panel) and from renal registries providing aggregated data (right panel). The incidence data for the Czech Republic and Slovakia only include dialysis patients. The mean and median age for Slovakia is based on dialysis patients and for Turkey only on haemodialysis patients. Dutch- and French-speaking Belgium, the Spanish regions of Cantabria, Castile and León and Castile-La Mancha and the UK; England, Northern Ireland and Wales do not report on patients younger than 20 years.
© Copyright Policy - creative-commons
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4440462&req=5

SFV014F2: Incidence of RRT, pmp at Day 1 in 2012, unadjusted (black bars) and standardized to the age and gender distribution of the EU27 population in 2010 (grey bars) and the mean and median age (years) at the start of RRT. Data are from renal registries providing individual level patient data (left panel) and from renal registries providing aggregated data (right panel). The incidence data for the Czech Republic and Slovakia only include dialysis patients. The mean and median age for Slovakia is based on dialysis patients and for Turkey only on haemodialysis patients. Dutch- and French-speaking Belgium, the Spanish regions of Cantabria, Castile and León and Castile-La Mancha and the UK; England, Northern Ireland and Wales do not report on patients younger than 20 years.
Mentions: In 2012, the total number of patients starting RRT for ESRD among all the registries reporting to the ERA-EDTA Registry was 69 035. These registries covered a total population of 629.7 million, resulting in an unadjusted incidence rate of 109.6 per million population (pmp). Figure 1A and Figure 2 show the incidence of ESRD patients receiving RRT per pmp on Day 1, among all national and regional renal registries in 30 countries reporting to the ERA-EDTA Registry in 2012. The highest unadjusted incidence rates were reported in Portugal (219.9 pmp), Greece (209.7 pmp) and Georgia (199.6 pmp), whereas the lowest unadjusted incidence rates were reported in Montenegro (24.2 pmp), Ukraine (27.6 pmp) and Russia (48.1 pmp). The incidence rate standardized for the EU27 population was highest in Israel (280.5 pmp), Georgia (227.5 pmp) and French-speaking Belgium (201.1 pmp). The mean age at the start of RRT across Europe was 62.0 years in the renal registries providing individual level patient data and 58.2 years in the renal registries providing aggregated data (Figure 2). Figure 1B and Figure 3 provide information on the incidence of RRT, per million age-related population (pmarp), on Day 1 for older patients. For the countries providing individual level data; the incidence of RRT for patients aged 65–74 years or 75 years and over varied considerably between the renal registries (Figure 3). The lowest incidence rate of patients aged 65–74 and 75 years and over was reported in Finland (199.8 and 220.8 pmarp, respectively). A more than three times as high incidence rate was reported in French-speaking Belgium (619.4 pmarp) for patients aged 65–74 years and Dutch-speaking Belgium (893.6 pmarp) for patients aged over 75 years (Figure 3). Within each country or region, there was a wide variation in the proportion of ESRD patients aged 75 years and over commencing RRT with the highest proportion reported in Dutch-speaking Belgium (44%) and Greece (43%) and the lowest proportion in Romania (15%) and Serbia (15%). Within the countries supplying individual level data, the four national or regional registries with the highest adjusted incidence of RRT on Day 1 (Greece, French- and Dutch-speaking Belgium and France) also had the highest incidence of RRT on Day 1 for patients 75 years and over (Figure 1A–B and 3).Fig. 2.

Bottom Line: The proportion of prevalent patients ≥75 years varied from 11 to 32% between countries.The overall renal transplantation rate in 2012 was 28.3 pmp (n = 15 673), with the highest rate seen in the Spanish region of Catalonia.Five-year adjusted survival for all RRT patients was 59.7% (95% confidence interval, CI: 59.3-60.0) which fell to 39.3% (95% CI: 38.7-39.9) in patients 65-74 years and 21.3% (95% CI: 20.8-21.9) in patients ≥75 years.

View Article: PubMed Central - PubMed

Affiliation: ERA-EDTA Registry, Department of Medical Informatics, Academic Medical Center, Universiteit van Amsterdam , Amsterdam , the Netherlands.

ABSTRACT

Background: This article summarizes the 2012 European Renal Association-European Dialysis and Transplant Association Registry Annual Report (available at www.era-edta-reg.org) with a specific focus on older patients (defined as ≥65 years).

Methods: Data provided by 45 national or regional renal registries in 30 countries in Europe and bordering the Mediterranean Sea were used. Individual patient level data were received from 31 renal registries, whereas 14 renal registries contributed data in an aggregated form. The incidence, prevalence and survival probabilities of patients with end-stage renal disease (ESRD) receiving renal replacement therapy (RRT) and renal transplantation rates for 2012 are presented.

Results: In 2012, the overall unadjusted incidence rate of patients with ESRD receiving RRT was 109.6 per million population (pmp) (n = 69 035), ranging from 219.9 pmp in Portugal to 24.2 pmp in Montenegro. The proportion of incident patients ≥75 years varied from 15 to 44% between countries. The overall unadjusted prevalence on 31 December 2012 was 716.7 pmp (n = 451 270), ranging from 1670.2 pmp in Portugal to 146.7 pmp in the Ukraine. The proportion of prevalent patients ≥75 years varied from 11 to 32% between countries. The overall renal transplantation rate in 2012 was 28.3 pmp (n = 15 673), with the highest rate seen in the Spanish region of Catalonia. The proportion of patients ≥65 years receiving a transplant ranged from 0 to 35%. Five-year adjusted survival for all RRT patients was 59.7% (95% confidence interval, CI: 59.3-60.0) which fell to 39.3% (95% CI: 38.7-39.9) in patients 65-74 years and 21.3% (95% CI: 20.8-21.9) in patients ≥75 years.

No MeSH data available.


Related in: MedlinePlus