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Multicomponent signal unmixing from nanoheterostructures: overcoming the traditional challenges of nanoscale X-ray analysis via machine learning.

Rossouw D, Burdet P, de la Peña F, Ducati C, Knappett BR, Wheatley AE, Midgley PA - Nano Lett. (2015)

Bottom Line: The chemical composition of core-shell nanoparticle clusters have been determined through principal component analysis (PCA) and independent component analysis (ICA) of an energy-dispersive X-ray (EDX) spectrum image (SI) acquired in a scanning transmission electron microscope (STEM).The method blindly decomposes the SI into three components, which are found to accurately represent the isolated and unmixed X-ray signals originating from the supporting carbon film, the shell, and the bimetallic core.The composition of the latter is verified by and is in excellent agreement with the separate quantification of bare bimetallic seed nanoparticles.

View Article: PubMed Central - PubMed

Affiliation: †Department of Materials Science and Metallurgy, University of Cambridge, 27 Charles Babbage Road, Cambridge CB3 0FS, United Kingdom.

ABSTRACT
The chemical composition of core-shell nanoparticle clusters have been determined through principal component analysis (PCA) and independent component analysis (ICA) of an energy-dispersive X-ray (EDX) spectrum image (SI) acquired in a scanning transmission electron microscope (STEM). The method blindly decomposes the SI into three components, which are found to accurately represent the isolated and unmixed X-ray signals originating from the supporting carbon film, the shell, and the bimetallic core. The composition of the latter is verified by and is in excellent agreement with the separate quantification of bare bimetallic seed nanoparticles.

No MeSH data available.


Related in: MedlinePlus

ICA of a cluster of bimetallic platinum/ironnanoparticle seedscoated by Fe3O4 shells. (a) HAADF STEM imagedisplays the core–shell structure of the nanoparticles. (b)Scree plot of the first 50 principal components showing the firstthree components lying above the noise. (c–e) Element mapsof (c) platinum, (d) iron, and (e) oxygen. (f–h). The IC maps(f) IC#0, (g) IC#1, and (h) IC#2 and (i) the corresponding IC spectra.
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fig4: ICA of a cluster of bimetallic platinum/ironnanoparticle seedscoated by Fe3O4 shells. (a) HAADF STEM imagedisplays the core–shell structure of the nanoparticles. (b)Scree plot of the first 50 principal components showing the firstthree components lying above the noise. (c–e) Element mapsof (c) platinum, (d) iron, and (e) oxygen. (f–h). The IC maps(f) IC#0, (g) IC#1, and (h) IC#2 and (i) the corresponding IC spectra.

Mentions: Across the sample theparticle morphologies were found to havea mean core diameter of approximately 3.3 nm and mean shell thicknessof approximately 1.7 nm (Figure 4a). Also visiblewere pure iron oxide particles (in the lower right-hand corner ofFigure 4a).


Multicomponent signal unmixing from nanoheterostructures: overcoming the traditional challenges of nanoscale X-ray analysis via machine learning.

Rossouw D, Burdet P, de la Peña F, Ducati C, Knappett BR, Wheatley AE, Midgley PA - Nano Lett. (2015)

ICA of a cluster of bimetallic platinum/ironnanoparticle seedscoated by Fe3O4 shells. (a) HAADF STEM imagedisplays the core–shell structure of the nanoparticles. (b)Scree plot of the first 50 principal components showing the firstthree components lying above the noise. (c–e) Element mapsof (c) platinum, (d) iron, and (e) oxygen. (f–h). The IC maps(f) IC#0, (g) IC#1, and (h) IC#2 and (i) the corresponding IC spectra.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4440406&req=5

fig4: ICA of a cluster of bimetallic platinum/ironnanoparticle seedscoated by Fe3O4 shells. (a) HAADF STEM imagedisplays the core–shell structure of the nanoparticles. (b)Scree plot of the first 50 principal components showing the firstthree components lying above the noise. (c–e) Element mapsof (c) platinum, (d) iron, and (e) oxygen. (f–h). The IC maps(f) IC#0, (g) IC#1, and (h) IC#2 and (i) the corresponding IC spectra.
Mentions: Across the sample theparticle morphologies were found to havea mean core diameter of approximately 3.3 nm and mean shell thicknessof approximately 1.7 nm (Figure 4a). Also visiblewere pure iron oxide particles (in the lower right-hand corner ofFigure 4a).

Bottom Line: The chemical composition of core-shell nanoparticle clusters have been determined through principal component analysis (PCA) and independent component analysis (ICA) of an energy-dispersive X-ray (EDX) spectrum image (SI) acquired in a scanning transmission electron microscope (STEM).The method blindly decomposes the SI into three components, which are found to accurately represent the isolated and unmixed X-ray signals originating from the supporting carbon film, the shell, and the bimetallic core.The composition of the latter is verified by and is in excellent agreement with the separate quantification of bare bimetallic seed nanoparticles.

View Article: PubMed Central - PubMed

Affiliation: †Department of Materials Science and Metallurgy, University of Cambridge, 27 Charles Babbage Road, Cambridge CB3 0FS, United Kingdom.

ABSTRACT
The chemical composition of core-shell nanoparticle clusters have been determined through principal component analysis (PCA) and independent component analysis (ICA) of an energy-dispersive X-ray (EDX) spectrum image (SI) acquired in a scanning transmission electron microscope (STEM). The method blindly decomposes the SI into three components, which are found to accurately represent the isolated and unmixed X-ray signals originating from the supporting carbon film, the shell, and the bimetallic core. The composition of the latter is verified by and is in excellent agreement with the separate quantification of bare bimetallic seed nanoparticles.

No MeSH data available.


Related in: MedlinePlus