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The Day-Hospital of the University Hospital, Bobo Dioulasso: An Example of Optimized HIV Management in Southern Burkina Faso.

Chas J, Hema A, Slama L, Kabore NF, Lescure FX, Fontaine C, Pialoux G, Sawadogo A - PLoS ONE (2015)

Bottom Line: The percentage of PtHIV lost to follow-up, untreated for HIV and deaths all decreased after 2005.Virological success increased due to a decrease in time to initiation of ARV treatment and an increase in percentage of patients treated (90.5% in 2012, mainly with 1st line drugs).Our day-hospital is a good example of the implementation of a specialist centre for the management of PtHIV in a resource-limited country (Burkina Faso).

View Article: PubMed Central - PubMed

Affiliation: Service des Maladies Infectieuses et Tropicales, Hôpital Tenon, Paris, France.

ABSTRACT

Objectives: To evaluate the epidemiological evolution of patients with HIV (PtHIV), between 2002 and 2012, in a day-hospital that became an HIV reference centre for south-west Burkina Faso.

Materials and methods: This was a retrospective study of PtHIV followed in the Bobo Dioulasso university hospital since 2002. The study was based on clinical data recorded using ESOPE software and analysed using Excel and SAS.

Results: A total of 7320 patients have been treated at the centre since 2002; the active file of patients increased from 147 in 2002 to 3684 patients in 2012. Mean age was stable at 38.4 years and the majority were female (71%). The delay to initiation of antiretroviral (ARV) treatment after HIV diagnosis decreased from 12.9 months in 2002 to 7.2 months in 2012. The percentage of PtHIV lost to follow-up, untreated for HIV and deaths all decreased after 2005. Voluntary anonymous screening and/or an evocative clinical picture were the main reasons for HIV diagnosis, usually at a late stage (41.1% at WHO stage 3). Virological success increased due to a decrease in time to initiation of ARV treatment and an increase in percentage of patients treated (90.5% in 2012, mainly with 1st line drugs). However, there was also a slight increase in the rate of therapeutic failures and the percentage of patients who progressed to 2nd or 3rd line-ARVs.

Conclusion: Our day-hospital is a good example of the implementation of a specialist centre for the management of PtHIV in a resource-limited country (Burkina Faso).

No MeSH data available.


Survival probability curve according to antiretroviral therapy among the HIV infected patients cohort at the Bobo-Dioulasso day hospital between 2002 and 2012.(test de Breslow-Gehan-Wilcoxon P<10–4).
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pone.0125588.g004: Survival probability curve according to antiretroviral therapy among the HIV infected patients cohort at the Bobo-Dioulasso day hospital between 2002 and 2012.(test de Breslow-Gehan-Wilcoxon P<10–4).

Mentions: The annual mortality rate evolved in the same way between 2002 and 2012, with an increase until 2004 (9.1%) and then a decrease to 2.1% in 2012 (Fig 3 and Fig 4).


The Day-Hospital of the University Hospital, Bobo Dioulasso: An Example of Optimized HIV Management in Southern Burkina Faso.

Chas J, Hema A, Slama L, Kabore NF, Lescure FX, Fontaine C, Pialoux G, Sawadogo A - PLoS ONE (2015)

Survival probability curve according to antiretroviral therapy among the HIV infected patients cohort at the Bobo-Dioulasso day hospital between 2002 and 2012.(test de Breslow-Gehan-Wilcoxon P<10–4).
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4430172&req=5

pone.0125588.g004: Survival probability curve according to antiretroviral therapy among the HIV infected patients cohort at the Bobo-Dioulasso day hospital between 2002 and 2012.(test de Breslow-Gehan-Wilcoxon P<10–4).
Mentions: The annual mortality rate evolved in the same way between 2002 and 2012, with an increase until 2004 (9.1%) and then a decrease to 2.1% in 2012 (Fig 3 and Fig 4).

Bottom Line: The percentage of PtHIV lost to follow-up, untreated for HIV and deaths all decreased after 2005.Virological success increased due to a decrease in time to initiation of ARV treatment and an increase in percentage of patients treated (90.5% in 2012, mainly with 1st line drugs).Our day-hospital is a good example of the implementation of a specialist centre for the management of PtHIV in a resource-limited country (Burkina Faso).

View Article: PubMed Central - PubMed

Affiliation: Service des Maladies Infectieuses et Tropicales, Hôpital Tenon, Paris, France.

ABSTRACT

Objectives: To evaluate the epidemiological evolution of patients with HIV (PtHIV), between 2002 and 2012, in a day-hospital that became an HIV reference centre for south-west Burkina Faso.

Materials and methods: This was a retrospective study of PtHIV followed in the Bobo Dioulasso university hospital since 2002. The study was based on clinical data recorded using ESOPE software and analysed using Excel and SAS.

Results: A total of 7320 patients have been treated at the centre since 2002; the active file of patients increased from 147 in 2002 to 3684 patients in 2012. Mean age was stable at 38.4 years and the majority were female (71%). The delay to initiation of antiretroviral (ARV) treatment after HIV diagnosis decreased from 12.9 months in 2002 to 7.2 months in 2012. The percentage of PtHIV lost to follow-up, untreated for HIV and deaths all decreased after 2005. Voluntary anonymous screening and/or an evocative clinical picture were the main reasons for HIV diagnosis, usually at a late stage (41.1% at WHO stage 3). Virological success increased due to a decrease in time to initiation of ARV treatment and an increase in percentage of patients treated (90.5% in 2012, mainly with 1st line drugs). However, there was also a slight increase in the rate of therapeutic failures and the percentage of patients who progressed to 2nd or 3rd line-ARVs.

Conclusion: Our day-hospital is a good example of the implementation of a specialist centre for the management of PtHIV in a resource-limited country (Burkina Faso).

No MeSH data available.