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The Day-Hospital of the University Hospital, Bobo Dioulasso: An Example of Optimized HIV Management in Southern Burkina Faso.

Chas J, Hema A, Slama L, Kabore NF, Lescure FX, Fontaine C, Pialoux G, Sawadogo A - PLoS ONE (2015)

Bottom Line: The percentage of PtHIV lost to follow-up, untreated for HIV and deaths all decreased after 2005.Virological success increased due to a decrease in time to initiation of ARV treatment and an increase in percentage of patients treated (90.5% in 2012, mainly with 1st line drugs).Our day-hospital is a good example of the implementation of a specialist centre for the management of PtHIV in a resource-limited country (Burkina Faso).

View Article: PubMed Central - PubMed

Affiliation: Service des Maladies Infectieuses et Tropicales, Hôpital Tenon, Paris, France.

ABSTRACT

Objectives: To evaluate the epidemiological evolution of patients with HIV (PtHIV), between 2002 and 2012, in a day-hospital that became an HIV reference centre for south-west Burkina Faso.

Materials and methods: This was a retrospective study of PtHIV followed in the Bobo Dioulasso university hospital since 2002. The study was based on clinical data recorded using ESOPE software and analysed using Excel and SAS.

Results: A total of 7320 patients have been treated at the centre since 2002; the active file of patients increased from 147 in 2002 to 3684 patients in 2012. Mean age was stable at 38.4 years and the majority were female (71%). The delay to initiation of antiretroviral (ARV) treatment after HIV diagnosis decreased from 12.9 months in 2002 to 7.2 months in 2012. The percentage of PtHIV lost to follow-up, untreated for HIV and deaths all decreased after 2005. Voluntary anonymous screening and/or an evocative clinical picture were the main reasons for HIV diagnosis, usually at a late stage (41.1% at WHO stage 3). Virological success increased due to a decrease in time to initiation of ARV treatment and an increase in percentage of patients treated (90.5% in 2012, mainly with 1st line drugs). However, there was also a slight increase in the rate of therapeutic failures and the percentage of patients who progressed to 2nd or 3rd line-ARVs.

Conclusion: Our day-hospital is a good example of the implementation of a specialist centre for the management of PtHIV in a resource-limited country (Burkina Faso).

No MeSH data available.


Socio-demographic characteristics of the study population.
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pone.0125588.g001: Socio-demographic characteristics of the study population.

Mentions: Over the 10 years of the study, the active file of PtHIV increased constantly from 147 patients in 2002 to 3684 patients in 2012. The median number of new cases per year was 695 [IQR: 145–979] and the number of news patients diagnosed yearly is reported in the Fig 1. The male/female ratio remained stable with a mean of 71.1% women and 28.9% men (Fig 1). Similarly, age also remained stable with a median age of 38.4 years [IQR: 31–44 years]; however, there was a trend towards older age in men (43 years; IQR: 37–48 years) than in women [36.6 years; IQR: 30–42 years] p<10–4. Seropositivity to HIV mainly concerned patients aged 15-45-years (78.2%) (only 21.8% of those >45 years).


The Day-Hospital of the University Hospital, Bobo Dioulasso: An Example of Optimized HIV Management in Southern Burkina Faso.

Chas J, Hema A, Slama L, Kabore NF, Lescure FX, Fontaine C, Pialoux G, Sawadogo A - PLoS ONE (2015)

Socio-demographic characteristics of the study population.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4430172&req=5

pone.0125588.g001: Socio-demographic characteristics of the study population.
Mentions: Over the 10 years of the study, the active file of PtHIV increased constantly from 147 patients in 2002 to 3684 patients in 2012. The median number of new cases per year was 695 [IQR: 145–979] and the number of news patients diagnosed yearly is reported in the Fig 1. The male/female ratio remained stable with a mean of 71.1% women and 28.9% men (Fig 1). Similarly, age also remained stable with a median age of 38.4 years [IQR: 31–44 years]; however, there was a trend towards older age in men (43 years; IQR: 37–48 years) than in women [36.6 years; IQR: 30–42 years] p<10–4. Seropositivity to HIV mainly concerned patients aged 15-45-years (78.2%) (only 21.8% of those >45 years).

Bottom Line: The percentage of PtHIV lost to follow-up, untreated for HIV and deaths all decreased after 2005.Virological success increased due to a decrease in time to initiation of ARV treatment and an increase in percentage of patients treated (90.5% in 2012, mainly with 1st line drugs).Our day-hospital is a good example of the implementation of a specialist centre for the management of PtHIV in a resource-limited country (Burkina Faso).

View Article: PubMed Central - PubMed

Affiliation: Service des Maladies Infectieuses et Tropicales, Hôpital Tenon, Paris, France.

ABSTRACT

Objectives: To evaluate the epidemiological evolution of patients with HIV (PtHIV), between 2002 and 2012, in a day-hospital that became an HIV reference centre for south-west Burkina Faso.

Materials and methods: This was a retrospective study of PtHIV followed in the Bobo Dioulasso university hospital since 2002. The study was based on clinical data recorded using ESOPE software and analysed using Excel and SAS.

Results: A total of 7320 patients have been treated at the centre since 2002; the active file of patients increased from 147 in 2002 to 3684 patients in 2012. Mean age was stable at 38.4 years and the majority were female (71%). The delay to initiation of antiretroviral (ARV) treatment after HIV diagnosis decreased from 12.9 months in 2002 to 7.2 months in 2012. The percentage of PtHIV lost to follow-up, untreated for HIV and deaths all decreased after 2005. Voluntary anonymous screening and/or an evocative clinical picture were the main reasons for HIV diagnosis, usually at a late stage (41.1% at WHO stage 3). Virological success increased due to a decrease in time to initiation of ARV treatment and an increase in percentage of patients treated (90.5% in 2012, mainly with 1st line drugs). However, there was also a slight increase in the rate of therapeutic failures and the percentage of patients who progressed to 2nd or 3rd line-ARVs.

Conclusion: Our day-hospital is a good example of the implementation of a specialist centre for the management of PtHIV in a resource-limited country (Burkina Faso).

No MeSH data available.