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Evaluating the tolerability and acceptability of an alcohol-based hand rub - real-life experience with the WHO protocol.

Wolfensberger A, Durisch N, Mertin J, Ajdler-Schaeffler E, Sax H - Antimicrob Resist Infect Control (2015)

Bottom Line: EVO9 was well tolerated and accepted according to the WHO single ABHR evaluation protocol with the potential for improvement for stickiness.The WHO protocol is feasible but requires considerable time and logistics.It does not preclude bias, in this case especially due to the necessary switch to personal dispensers.

View Article: PubMed Central - PubMed

Affiliation: Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zürich, University of Zürich, Raemistrasse 100, Zurich, CH-8091 Switzerland.

ABSTRACT

Background: Optimizing user satisfaction with alcohol-based hand rubs (ABHR) may be vital to enhance hand hygiene performance. This study tested the tolerability and acceptability of a new ABHR (EVO9; Ecolab) in healthcare workers under daily working conditions and evaluated the practicability of the corresponding WHO protocol.

Methods: We strictly applied the WHO single product ABHR evaluation protocol. A trained observer assessed hand skin conditions of healthy volunteers using at least 30 ml ABHR per day during their clinical work at baseline, day 3-5 and one month (visit 1-3). Participants rated ABHR tolerability and acceptability at visit 2 and 3. Additionally, we registered study time for participants and study team.

Results: Among 46 volunteers, 76% were female; 37% nurses, 28% physicians. Skin was observer-rated "not" or "incidentally" dry in 64.4%, 77.8%, and 90.9% participants at visit 1, 2, and 3, respectively. EVO9 was scored ≥5 (progressive scale, 1-7) for appearance, intactness, moisture content, and sensation by 95.7%, 97.7%, 88.9%, and 97.8% participants at visit 3, respectively. All WHO benchmarks were exceeded except for "speed of drying" at visit 2, and "texture" at visit 2 and 3. Cumulative study time expenditure was 14 days for the observer and four days for participants.

Conclusions: EVO9 was well tolerated and accepted according to the WHO single ABHR evaluation protocol with the potential for improvement for stickiness. The WHO protocol is feasible but requires considerable time and logistics. It does not preclude bias, in this case especially due to the necessary switch to personal dispensers.

No MeSH data available.


Product acceptability by participant evaluation. Proportion of participants rating skin tolerability items (Likert scale 1 to 7) > 4; dashed line, WHO minimal pass criteria for alcohol-based hand rub. Visit 2 took place at day 3–5 and visit 3 at one month of test alcohol-based hand rub use.
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Fig2: Product acceptability by participant evaluation. Proportion of participants rating skin tolerability items (Likert scale 1 to 7) > 4; dashed line, WHO minimal pass criteria for alcohol-based hand rub. Visit 2 took place at day 3–5 and visit 3 at one month of test alcohol-based hand rub use.

Mentions: The WHO criteria for product acceptability for the items color and fragrance was fulfilled at each time point. The WHO criteria for all the other items were met in all but two categories at visit 2 and in all but one category at visit 3. The investigational product failed to meet the WHO criterion for acceptability by study participants only for texture at visits 2 and 3 and speed of drying at visit 2. Additionally, while still meeting WHO benchmark ‘smell after application’ received lower scores than the other items (Figure 2).Figure 2


Evaluating the tolerability and acceptability of an alcohol-based hand rub - real-life experience with the WHO protocol.

Wolfensberger A, Durisch N, Mertin J, Ajdler-Schaeffler E, Sax H - Antimicrob Resist Infect Control (2015)

Product acceptability by participant evaluation. Proportion of participants rating skin tolerability items (Likert scale 1 to 7) > 4; dashed line, WHO minimal pass criteria for alcohol-based hand rub. Visit 2 took place at day 3–5 and visit 3 at one month of test alcohol-based hand rub use.
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC4419417&req=5

Fig2: Product acceptability by participant evaluation. Proportion of participants rating skin tolerability items (Likert scale 1 to 7) > 4; dashed line, WHO minimal pass criteria for alcohol-based hand rub. Visit 2 took place at day 3–5 and visit 3 at one month of test alcohol-based hand rub use.
Mentions: The WHO criteria for product acceptability for the items color and fragrance was fulfilled at each time point. The WHO criteria for all the other items were met in all but two categories at visit 2 and in all but one category at visit 3. The investigational product failed to meet the WHO criterion for acceptability by study participants only for texture at visits 2 and 3 and speed of drying at visit 2. Additionally, while still meeting WHO benchmark ‘smell after application’ received lower scores than the other items (Figure 2).Figure 2

Bottom Line: EVO9 was well tolerated and accepted according to the WHO single ABHR evaluation protocol with the potential for improvement for stickiness.The WHO protocol is feasible but requires considerable time and logistics.It does not preclude bias, in this case especially due to the necessary switch to personal dispensers.

View Article: PubMed Central - PubMed

Affiliation: Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zürich, University of Zürich, Raemistrasse 100, Zurich, CH-8091 Switzerland.

ABSTRACT

Background: Optimizing user satisfaction with alcohol-based hand rubs (ABHR) may be vital to enhance hand hygiene performance. This study tested the tolerability and acceptability of a new ABHR (EVO9; Ecolab) in healthcare workers under daily working conditions and evaluated the practicability of the corresponding WHO protocol.

Methods: We strictly applied the WHO single product ABHR evaluation protocol. A trained observer assessed hand skin conditions of healthy volunteers using at least 30 ml ABHR per day during their clinical work at baseline, day 3-5 and one month (visit 1-3). Participants rated ABHR tolerability and acceptability at visit 2 and 3. Additionally, we registered study time for participants and study team.

Results: Among 46 volunteers, 76% were female; 37% nurses, 28% physicians. Skin was observer-rated "not" or "incidentally" dry in 64.4%, 77.8%, and 90.9% participants at visit 1, 2, and 3, respectively. EVO9 was scored ≥5 (progressive scale, 1-7) for appearance, intactness, moisture content, and sensation by 95.7%, 97.7%, 88.9%, and 97.8% participants at visit 3, respectively. All WHO benchmarks were exceeded except for "speed of drying" at visit 2, and "texture" at visit 2 and 3. Cumulative study time expenditure was 14 days for the observer and four days for participants.

Conclusions: EVO9 was well tolerated and accepted according to the WHO single ABHR evaluation protocol with the potential for improvement for stickiness. The WHO protocol is feasible but requires considerable time and logistics. It does not preclude bias, in this case especially due to the necessary switch to personal dispensers.

No MeSH data available.