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Representation of Sound Objects within Early-Stage Auditory Areas: A Repetition Effect Study Using 7T fMRI.

Da Costa S, Bourquin NM, Knebel JF, Saenz M, van der Zwaag W, Clarke S - PLoS ONE (2015)

Bottom Line: The primary auditory cortex was identified by means of tonotopic mapping and the non-primary areas by comparison with previous histological studies.This effect was found within the right hemisphere in primary areas A1 and R as well as two non-primary areas on the antero-medial part of the planum temporale, and within the left hemisphere in A1 and a non-primary area on the medial part of Heschl's gyrus.Thus, several, but not all early-stage auditory areas encode the meaning of environmental sounds.

View Article: PubMed Central - PubMed

Affiliation: Service de Neuropsychologie et de Neuroréhabilitation, Département des Neurosciences Cliniques, Centre Hospitalier Universitaire Vaudois, Université de Lausanne, Lausanne, Switzerland.

ABSTRACT
Environmental sounds are highly complex stimuli whose recognition depends on the interaction of top-down and bottom-up processes in the brain. Their semantic representations were shown to yield repetition suppression effects, i. e. a decrease in activity during exposure to a sound that is perceived as belonging to the same source as a preceding sound. Making use of the high spatial resolution of 7T fMRI we have investigated the representations of sound objects within early-stage auditory areas on the supratemporal plane. The primary auditory cortex was identified by means of tonotopic mapping and the non-primary areas by comparison with previous histological studies. Repeated presentations of different exemplars of the same sound source, as compared to the presentation of different sound sources, yielded significant repetition suppression effects within a subset of early-stage areas. This effect was found within the right hemisphere in primary areas A1 and R as well as two non-primary areas on the antero-medial part of the planum temporale, and within the left hemisphere in A1 and a non-primary area on the medial part of Heschl's gyrus. Thus, several, but not all early-stage auditory areas encode the meaning of environmental sounds.

No MeSH data available.


Related in: MedlinePlus

Time frame by time frame 2-way ANOVA condition (REP, CTRL) x hemisphere (RH, LH) for each of the 10 early stage areas (A1, R, L1, L2, L3, L4, M1, M2, M3, M4).Gray shading highlights the rise and decay periods, red hues denote significant effects at a given time point and area. During the plateau phase a significant main effect of condition was present in A1, R, M1, M2, M3 and M4 as well as a significant main effect of hemisphere at isolated time points in M1 and M2.
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pone.0124072.g005: Time frame by time frame 2-way ANOVA condition (REP, CTRL) x hemisphere (RH, LH) for each of the 10 early stage areas (A1, R, L1, L2, L3, L4, M1, M2, M3, M4).Gray shading highlights the rise and decay periods, red hues denote significant effects at a given time point and area. During the plateau phase a significant main effect of condition was present in A1, R, M1, M2, M3 and M4 as well as a significant main effect of hemisphere at isolated time points in M1 and M2.

Mentions: A time-point-per-time-point 2 x 2 ANOVA (Hemisphere x Condition) on the BOLD time-courses revealed a main effect of condition during the plateau phase in 6 areas, A1, R, M1, M2, M3, M4 and L4 (Fig 5, left panel, p<0.05, uncorrected). A main effect of hemisphere was present during the plateau phase in 2 areas, M1 and M2 (Fig 5, middle panel, p<0.05, uncorrected). No significant interaction Hemisphere x Condition was observed during the plateau phase (Fig 5, right panel).


Representation of Sound Objects within Early-Stage Auditory Areas: A Repetition Effect Study Using 7T fMRI.

Da Costa S, Bourquin NM, Knebel JF, Saenz M, van der Zwaag W, Clarke S - PLoS ONE (2015)

Time frame by time frame 2-way ANOVA condition (REP, CTRL) x hemisphere (RH, LH) for each of the 10 early stage areas (A1, R, L1, L2, L3, L4, M1, M2, M3, M4).Gray shading highlights the rise and decay periods, red hues denote significant effects at a given time point and area. During the plateau phase a significant main effect of condition was present in A1, R, M1, M2, M3 and M4 as well as a significant main effect of hemisphere at isolated time points in M1 and M2.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4418571&req=5

pone.0124072.g005: Time frame by time frame 2-way ANOVA condition (REP, CTRL) x hemisphere (RH, LH) for each of the 10 early stage areas (A1, R, L1, L2, L3, L4, M1, M2, M3, M4).Gray shading highlights the rise and decay periods, red hues denote significant effects at a given time point and area. During the plateau phase a significant main effect of condition was present in A1, R, M1, M2, M3 and M4 as well as a significant main effect of hemisphere at isolated time points in M1 and M2.
Mentions: A time-point-per-time-point 2 x 2 ANOVA (Hemisphere x Condition) on the BOLD time-courses revealed a main effect of condition during the plateau phase in 6 areas, A1, R, M1, M2, M3, M4 and L4 (Fig 5, left panel, p<0.05, uncorrected). A main effect of hemisphere was present during the plateau phase in 2 areas, M1 and M2 (Fig 5, middle panel, p<0.05, uncorrected). No significant interaction Hemisphere x Condition was observed during the plateau phase (Fig 5, right panel).

Bottom Line: The primary auditory cortex was identified by means of tonotopic mapping and the non-primary areas by comparison with previous histological studies.This effect was found within the right hemisphere in primary areas A1 and R as well as two non-primary areas on the antero-medial part of the planum temporale, and within the left hemisphere in A1 and a non-primary area on the medial part of Heschl's gyrus.Thus, several, but not all early-stage auditory areas encode the meaning of environmental sounds.

View Article: PubMed Central - PubMed

Affiliation: Service de Neuropsychologie et de Neuroréhabilitation, Département des Neurosciences Cliniques, Centre Hospitalier Universitaire Vaudois, Université de Lausanne, Lausanne, Switzerland.

ABSTRACT
Environmental sounds are highly complex stimuli whose recognition depends on the interaction of top-down and bottom-up processes in the brain. Their semantic representations were shown to yield repetition suppression effects, i. e. a decrease in activity during exposure to a sound that is perceived as belonging to the same source as a preceding sound. Making use of the high spatial resolution of 7T fMRI we have investigated the representations of sound objects within early-stage auditory areas on the supratemporal plane. The primary auditory cortex was identified by means of tonotopic mapping and the non-primary areas by comparison with previous histological studies. Repeated presentations of different exemplars of the same sound source, as compared to the presentation of different sound sources, yielded significant repetition suppression effects within a subset of early-stage areas. This effect was found within the right hemisphere in primary areas A1 and R as well as two non-primary areas on the antero-medial part of the planum temporale, and within the left hemisphere in A1 and a non-primary area on the medial part of Heschl's gyrus. Thus, several, but not all early-stage auditory areas encode the meaning of environmental sounds.

No MeSH data available.


Related in: MedlinePlus