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Severe malaria in Canada, 2001-2013.

McCarthy AE, Morgan C, Prematunge C, Geduld J - Malar. J. (2015)

Bottom Line: Overall use and appropriateness of pre-travel advice and chemoprophylaxis remains low.Most cases result from patient delays in recognizing symptoms and seeking appropriate medical attention.Improved understanding of this population can help target risk reduction strategies and interventions to limit personal susceptibility and healthcare treatment delays.

View Article: PubMed Central - PubMed

Affiliation: Division of Infectious Diseases, The Ottawa Hospital, 501 Smyth Road, Ottawa, ON, K1H 8L6, Canada. amccarthy@ottawahospital.on.ca.

ABSTRACT

Background: Imported malaria is the principal, preventable, life-threatening infection among Canadians travelling abroad. The Canadian Malaria Network supplies information and parenteral malaria therapy to healthcare providers treating severe and complicated malaria and gathers surveillance information on these cases.

Methods: Data were collected on the characteristics, risk factors, and clinical outcomes of severe malaria cases in Canada from June 2001 to December 2013.

Results: The need for parenteral therapy in Canada has increased in the last decade. The vast majority of cases are reported from Ontario and Quebec and occur among travellers to and from Africa. Regardless of country of birth, all persons originating from endemic and non-endemic countries are at a similar risk of malaria-related complications. Overall use and appropriateness of pre-travel advice and chemoprophylaxis remains low. Most cases result from patient delays in recognizing symptoms and seeking appropriate medical attention. Although some healthcare delays occurred in a select number of cases, the majority of patients were diagnosed quickly and were appropriately treated with parenteral therapy within a few hours of diagnosis.

Conclusions: Data from the Canadian Malaria Network provide insight into the characteristics of imported severe and complicated malaria infections in Canada. Improved understanding of this population can help target risk reduction strategies and interventions to limit personal susceptibility and healthcare treatment delays.

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Related in: MedlinePlus

Distribution of severe malaria cases by Canadian province and territory (n = 248). Legend: AB= Alberta, BC = British Columbia, MB = Manitoba, NB = New Brunswick, NL = Newfoundland & Labrador, NS = Nova Scotia, NT = Northwest Territories, NU = Nunavut, ON = Ontario, PE = Prince Edward Island, QC = Quebec, SK = Saskatchewan, YT = Yukon.
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Fig1: Distribution of severe malaria cases by Canadian province and territory (n = 248). Legend: AB= Alberta, BC = British Columbia, MB = Manitoba, NB = New Brunswick, NL = Newfoundland & Labrador, NS = Nova Scotia, NT = Northwest Territories, NU = Nunavut, ON = Ontario, PE = Prince Edward Island, QC = Quebec, SK = Saskatchewan, YT = Yukon.

Mentions: The overall incidence of severe malaria in Canada during the study period was 54 cases per 1,000 surveillance days. There was a gradual increase in annual incidence over time with the greatest number of cases occurring in 2013 (Table 1). Most Canadian provinces, with the exception of Prince Edward Island and the Territories, have requested treatment for one or more cases of severe malaria. The majority of requests (76%) occurred in Ontario and Quebec (Figure 1). Most requests for IV therapy (82%) occurred in cities with a CMN site or satellite site.Figure 1


Severe malaria in Canada, 2001-2013.

McCarthy AE, Morgan C, Prematunge C, Geduld J - Malar. J. (2015)

Distribution of severe malaria cases by Canadian province and territory (n = 248). Legend: AB= Alberta, BC = British Columbia, MB = Manitoba, NB = New Brunswick, NL = Newfoundland & Labrador, NS = Nova Scotia, NT = Northwest Territories, NU = Nunavut, ON = Ontario, PE = Prince Edward Island, QC = Quebec, SK = Saskatchewan, YT = Yukon.
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC4418046&req=5

Fig1: Distribution of severe malaria cases by Canadian province and territory (n = 248). Legend: AB= Alberta, BC = British Columbia, MB = Manitoba, NB = New Brunswick, NL = Newfoundland & Labrador, NS = Nova Scotia, NT = Northwest Territories, NU = Nunavut, ON = Ontario, PE = Prince Edward Island, QC = Quebec, SK = Saskatchewan, YT = Yukon.
Mentions: The overall incidence of severe malaria in Canada during the study period was 54 cases per 1,000 surveillance days. There was a gradual increase in annual incidence over time with the greatest number of cases occurring in 2013 (Table 1). Most Canadian provinces, with the exception of Prince Edward Island and the Territories, have requested treatment for one or more cases of severe malaria. The majority of requests (76%) occurred in Ontario and Quebec (Figure 1). Most requests for IV therapy (82%) occurred in cities with a CMN site or satellite site.Figure 1

Bottom Line: Overall use and appropriateness of pre-travel advice and chemoprophylaxis remains low.Most cases result from patient delays in recognizing symptoms and seeking appropriate medical attention.Improved understanding of this population can help target risk reduction strategies and interventions to limit personal susceptibility and healthcare treatment delays.

View Article: PubMed Central - PubMed

Affiliation: Division of Infectious Diseases, The Ottawa Hospital, 501 Smyth Road, Ottawa, ON, K1H 8L6, Canada. amccarthy@ottawahospital.on.ca.

ABSTRACT

Background: Imported malaria is the principal, preventable, life-threatening infection among Canadians travelling abroad. The Canadian Malaria Network supplies information and parenteral malaria therapy to healthcare providers treating severe and complicated malaria and gathers surveillance information on these cases.

Methods: Data were collected on the characteristics, risk factors, and clinical outcomes of severe malaria cases in Canada from June 2001 to December 2013.

Results: The need for parenteral therapy in Canada has increased in the last decade. The vast majority of cases are reported from Ontario and Quebec and occur among travellers to and from Africa. Regardless of country of birth, all persons originating from endemic and non-endemic countries are at a similar risk of malaria-related complications. Overall use and appropriateness of pre-travel advice and chemoprophylaxis remains low. Most cases result from patient delays in recognizing symptoms and seeking appropriate medical attention. Although some healthcare delays occurred in a select number of cases, the majority of patients were diagnosed quickly and were appropriately treated with parenteral therapy within a few hours of diagnosis.

Conclusions: Data from the Canadian Malaria Network provide insight into the characteristics of imported severe and complicated malaria infections in Canada. Improved understanding of this population can help target risk reduction strategies and interventions to limit personal susceptibility and healthcare treatment delays.

Show MeSH
Related in: MedlinePlus