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A Novel Operative Procedure for Pelvic Organ Prolapse Utilizing a MRI-Visible Mesh Implant: Safety and Outcome of Modified Laparoscopic Bilateral Sacropexy.

Joukhadar R, Meyberg-Solomayer G, Hamza A, Radosa J, Bader W, Barski D, Ismaeel F, Schneider G, Solomayer E, Baum S - Biomed Res Int (2015)

Bottom Line: Anatomical success was defined as POP-Q stage 0-I.MLBS is a feasible and safe procedure with favorable anatomical and functional outcome and good concomitant healing rates of SUI and OAB.Prospective data and larger samples are required.

View Article: PubMed Central - PubMed

Affiliation: Department of Obstetrics and Gynecology, University Hospital Homburg, Kirrberger Straße 100, 66424 Homburg, Germany.

ABSTRACT

Introduction: Sacropexy is a generally applied treatment of prolapse, yet there are known possible complications of it. An essential need exists for better alloplastic materials.

Methods: Between April 2013 and June 2014, we performed a modified laparoscopic bilateral sacropexy (MLBS) in 10 patients using a MRI-visible PVDF mesh implant. Selected patients had prolapse POP-Q stages II-III and concomitant OAB. We studied surgery-related morbidity, anatomical and functional outcome, and mesh-visibility in MRI. Mean follow-up was 7.4 months.

Results: Concomitant colporrhaphy was conducted in 1/10 patients. Anatomical success was defined as POP-Q stage 0-I. Apical success rate was 100% and remained stable. A recurrent cystocele was seen in 1/10 patients during follow-up without need for intervention. Out of 6 (6/10) patients with preoperative SUI, 5/6 were healed and 1/6 persisted. De-novo SUI was seen in 1/10 patients. Complications requiring a relaparoscopy were seen in 2/10 patients. 8/10 patients with OAB were relieved postoperatively. The first in-human magnetic resonance visualization of a prolapse mesh implant was performed and showed good quality of visualization.

Conclusion: MLBS is a feasible and safe procedure with favorable anatomical and functional outcome and good concomitant healing rates of SUI and OAB. Prospective data and larger samples are required.

No MeSH data available.


Related in: MedlinePlus

Correction of prolapse in each compartment. The dots correlate to the mean measurements of Aa, Ba, C, D, Ap, and Bp. Red line: lines out the preoperative status (POP-Q measurements). Green line: lines out the postoperative status (POP-Q measurements) before discharge.
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Related In: Results  -  Collection


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fig5: Correction of prolapse in each compartment. The dots correlate to the mean measurements of Aa, Ba, C, D, Ap, and Bp. Red line: lines out the preoperative status (POP-Q measurements). Green line: lines out the postoperative status (POP-Q measurements) before discharge.

Mentions: The difference between the pre- and postoperative status is lined out in Figure 5.


A Novel Operative Procedure for Pelvic Organ Prolapse Utilizing a MRI-Visible Mesh Implant: Safety and Outcome of Modified Laparoscopic Bilateral Sacropexy.

Joukhadar R, Meyberg-Solomayer G, Hamza A, Radosa J, Bader W, Barski D, Ismaeel F, Schneider G, Solomayer E, Baum S - Biomed Res Int (2015)

Correction of prolapse in each compartment. The dots correlate to the mean measurements of Aa, Ba, C, D, Ap, and Bp. Red line: lines out the preoperative status (POP-Q measurements). Green line: lines out the postoperative status (POP-Q measurements) before discharge.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4417564&req=5

fig5: Correction of prolapse in each compartment. The dots correlate to the mean measurements of Aa, Ba, C, D, Ap, and Bp. Red line: lines out the preoperative status (POP-Q measurements). Green line: lines out the postoperative status (POP-Q measurements) before discharge.
Mentions: The difference between the pre- and postoperative status is lined out in Figure 5.

Bottom Line: Anatomical success was defined as POP-Q stage 0-I.MLBS is a feasible and safe procedure with favorable anatomical and functional outcome and good concomitant healing rates of SUI and OAB.Prospective data and larger samples are required.

View Article: PubMed Central - PubMed

Affiliation: Department of Obstetrics and Gynecology, University Hospital Homburg, Kirrberger Straße 100, 66424 Homburg, Germany.

ABSTRACT

Introduction: Sacropexy is a generally applied treatment of prolapse, yet there are known possible complications of it. An essential need exists for better alloplastic materials.

Methods: Between April 2013 and June 2014, we performed a modified laparoscopic bilateral sacropexy (MLBS) in 10 patients using a MRI-visible PVDF mesh implant. Selected patients had prolapse POP-Q stages II-III and concomitant OAB. We studied surgery-related morbidity, anatomical and functional outcome, and mesh-visibility in MRI. Mean follow-up was 7.4 months.

Results: Concomitant colporrhaphy was conducted in 1/10 patients. Anatomical success was defined as POP-Q stage 0-I. Apical success rate was 100% and remained stable. A recurrent cystocele was seen in 1/10 patients during follow-up without need for intervention. Out of 6 (6/10) patients with preoperative SUI, 5/6 were healed and 1/6 persisted. De-novo SUI was seen in 1/10 patients. Complications requiring a relaparoscopy were seen in 2/10 patients. 8/10 patients with OAB were relieved postoperatively. The first in-human magnetic resonance visualization of a prolapse mesh implant was performed and showed good quality of visualization.

Conclusion: MLBS is a feasible and safe procedure with favorable anatomical and functional outcome and good concomitant healing rates of SUI and OAB. Prospective data and larger samples are required.

No MeSH data available.


Related in: MedlinePlus