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Investigation of flexural strength and cytotoxicity of acrylic resin copolymers by using different polymerization methods.

Sahin O, Ozdemir AK, Turgut M, Boztug A, Sumer Z - J Adv Prosthodont (2015)

Bottom Line: Within the conventional heat-polymerized group maximum transverse strength had been seen in the HEMA 2% concentration; however, when the concentration ratio increased, the strength decreased.In the injection-molded group, maximum transverse strength had been seen in the IBMA 2% concentration; also as the concentration ratio increased, the strength decreased.Within the limitations of this study, it may be concluded that IBMA and HEMA may be used in low concentration and at high temperature to obtain non-cytotoxic and durable copolymer structure.

View Article: PubMed Central - PubMed

Affiliation: Department of Prosthodontics, Faculty of Dentistry, Bülent Ecevit University, Zonguldak, Turkey.

ABSTRACT

Purpose: The aim of this study was to appraise the some mechanical properties of polymethyl methacrylate based denture base resin polymerized by copolymerization mechanism, and to investigate the cytotoxic effect of these copolymer resins.

Materials and methods: 2-hydroxyethyl methacrylate (HEMA) and isobutyl methacrylate (IBMA) were added to monomers of conventional heat polymerized and injection-molded poly methyl methacrylate (PMMA) resin contents of 2%, 3%, and 5% by volume and polymerization was carried out. Three-point bending test was performed to detect flexural strength and the elasticity modulus of the resins. To determine the statistical differences between the study groups, the Kruskall-Wallis test was performed. Then pairwise comparisons were performed between significant groups by Mann-Whitney U test. Agar-overlay test was performed to determine cytotoxic effect of copolymer resins. Chemical analysis was determined by FTIR spectrum.

Results: Synthesis of the copolymer was approved by FTIR spectroscopy. Within the conventional heat-polymerized group maximum transverse strength had been seen in the HEMA 2% concentration; however, when the concentration ratio increased, the strength decreased. In the injection-molded group, maximum transverse strength had been seen in the IBMA 2% concentration; also as the concentration ratio increased, the strength decreased. Only IBMA showed no cytotoxic effect at low concentrations when both two polymerization methods applied while HEMA showed cytotoxic effect in the injection-molded resins.

Conclusion: Within the limitations of this study, it may be concluded that IBMA and HEMA may be used in low concentration and at high temperature to obtain non-cytotoxic and durable copolymer structure.

No MeSH data available.


Related in: MedlinePlus

FTIR spectrum of Paladent Control and Paladent 20-IBMA Copolymers.
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Figure 1: FTIR spectrum of Paladent Control and Paladent 20-IBMA Copolymers.

Mentions: The copolymer synthesis was approved by FTIR spectroscopy. Fig. 1 shows the FTIR spectrum of Paladent 20 control, 2% IBMA, 3% IBMA, 5% IBMA, MMA monomer and IBMA monomer; Fig. 2 shows the FTIR spectrum of Paladent 20 control, 2% HEMA, 3% HEMA, 5% HEMA copolymers, MMA, and HEMA monomers; Fig. 3 shows the FTIR spectrum of Palaxpress control, 2% IBMA, 3% IBMA, 5% IBMA, MMA monomer, and IBMA monomer; Fig. 4 shows the FTIR spectrum of Palaxpress control, 2% HEMA, 3% HEMA, 5% HEMA, MMA monomer, and HEMA monomer; 'a' indicates the C-H; 'b' indicates the C=O ; 'c' and 'd' indicate C=C bonds. Bending of C=C which were observed in the MMA, IBMA and HEMA monomers, were not observed in both the control and the resin structure of the MMA-IBMA and MMA-HEMA copolymers. These findings are evidence of forming MMA-IBMA and MMA-HEMA copolymers as a result of polymerization by fragmentation of the double bonds between MMA, IBMA, HEMA monomers. When we look at the areas of peak amplitude wavelengths resulting from copolymerization, (approximately 1740-1050 cm-1) conventional heat-polymerized resins have higher peaks of amplitude than the injection-molded resins.


Investigation of flexural strength and cytotoxicity of acrylic resin copolymers by using different polymerization methods.

Sahin O, Ozdemir AK, Turgut M, Boztug A, Sumer Z - J Adv Prosthodont (2015)

FTIR spectrum of Paladent Control and Paladent 20-IBMA Copolymers.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4414953&req=5

Figure 1: FTIR spectrum of Paladent Control and Paladent 20-IBMA Copolymers.
Mentions: The copolymer synthesis was approved by FTIR spectroscopy. Fig. 1 shows the FTIR spectrum of Paladent 20 control, 2% IBMA, 3% IBMA, 5% IBMA, MMA monomer and IBMA monomer; Fig. 2 shows the FTIR spectrum of Paladent 20 control, 2% HEMA, 3% HEMA, 5% HEMA copolymers, MMA, and HEMA monomers; Fig. 3 shows the FTIR spectrum of Palaxpress control, 2% IBMA, 3% IBMA, 5% IBMA, MMA monomer, and IBMA monomer; Fig. 4 shows the FTIR spectrum of Palaxpress control, 2% HEMA, 3% HEMA, 5% HEMA, MMA monomer, and HEMA monomer; 'a' indicates the C-H; 'b' indicates the C=O ; 'c' and 'd' indicate C=C bonds. Bending of C=C which were observed in the MMA, IBMA and HEMA monomers, were not observed in both the control and the resin structure of the MMA-IBMA and MMA-HEMA copolymers. These findings are evidence of forming MMA-IBMA and MMA-HEMA copolymers as a result of polymerization by fragmentation of the double bonds between MMA, IBMA, HEMA monomers. When we look at the areas of peak amplitude wavelengths resulting from copolymerization, (approximately 1740-1050 cm-1) conventional heat-polymerized resins have higher peaks of amplitude than the injection-molded resins.

Bottom Line: Within the conventional heat-polymerized group maximum transverse strength had been seen in the HEMA 2% concentration; however, when the concentration ratio increased, the strength decreased.In the injection-molded group, maximum transverse strength had been seen in the IBMA 2% concentration; also as the concentration ratio increased, the strength decreased.Within the limitations of this study, it may be concluded that IBMA and HEMA may be used in low concentration and at high temperature to obtain non-cytotoxic and durable copolymer structure.

View Article: PubMed Central - PubMed

Affiliation: Department of Prosthodontics, Faculty of Dentistry, Bülent Ecevit University, Zonguldak, Turkey.

ABSTRACT

Purpose: The aim of this study was to appraise the some mechanical properties of polymethyl methacrylate based denture base resin polymerized by copolymerization mechanism, and to investigate the cytotoxic effect of these copolymer resins.

Materials and methods: 2-hydroxyethyl methacrylate (HEMA) and isobutyl methacrylate (IBMA) were added to monomers of conventional heat polymerized and injection-molded poly methyl methacrylate (PMMA) resin contents of 2%, 3%, and 5% by volume and polymerization was carried out. Three-point bending test was performed to detect flexural strength and the elasticity modulus of the resins. To determine the statistical differences between the study groups, the Kruskall-Wallis test was performed. Then pairwise comparisons were performed between significant groups by Mann-Whitney U test. Agar-overlay test was performed to determine cytotoxic effect of copolymer resins. Chemical analysis was determined by FTIR spectrum.

Results: Synthesis of the copolymer was approved by FTIR spectroscopy. Within the conventional heat-polymerized group maximum transverse strength had been seen in the HEMA 2% concentration; however, when the concentration ratio increased, the strength decreased. In the injection-molded group, maximum transverse strength had been seen in the IBMA 2% concentration; also as the concentration ratio increased, the strength decreased. Only IBMA showed no cytotoxic effect at low concentrations when both two polymerization methods applied while HEMA showed cytotoxic effect in the injection-molded resins.

Conclusion: Within the limitations of this study, it may be concluded that IBMA and HEMA may be used in low concentration and at high temperature to obtain non-cytotoxic and durable copolymer structure.

No MeSH data available.


Related in: MedlinePlus