Limits...
Normative database of retinal oximetry in Asian Indian eyes.

Mohan A, Dabir S, Yadav NK, Kummelil M, Kumar RS, Shetty R - PLoS ONE (2015)

Bottom Line: There was no significant change in the arterio-venous saturation difference (AVSD).Age, vessel diameter and OPP were the significant factors that influenced the saturation.Arteriolar and venous saturations increased with age while the AVSD did not change significantly.

View Article: PubMed Central - PubMed

Affiliation: Narayana Nethralaya, Post Graduate Institute of Ophthalmology, Bangalore, India.

ABSTRACT

Objective: To study the oxygen saturation profile in normal Asian Indian eyes.

Design: A cross sectional prospective study.

Subjects: Ninety eight consecutive patients presenting to our hospital with best corrected distance visual acuity (BCVA) of 20/20 and a normal ophthalmic examination were included in the study. Patients having any ocular or systemic disease were excluded from the study.

Materials and methods: Oximetry was performed on all subjects with the Oxymap T1 retinal oximeter (Oxymap hf, Reykjavik, Iceland).

Main outcome measures: The images were analysed for oxygen saturation and diameter.

Results: The mean age was 33 years (Range: 18-63; SD: 12.4). The average arteriolar saturation was 90.3 ± 6.6% and the venous saturation was 56.9% ± 6.3. The average A-V (arterio-venous) difference was 33.2% ± 5.2. There was an increase in arteriolar (R2 = 0.264; p=0.001) and venous saturation (R2 = 0.151; p=0.001) with age. There was no significant change in the arterio-venous saturation difference (AVSD). The inferotemporal quadrant had the lowest saturations. Age correlated positively with ocular perfusion pressure (OPP)(R2 = 0.07; p=0.007). OPP correlated positively with global arteriolar saturation (R2=0.057, p=0.018).

Conclusion: This study provides the normative database for an Indian population and is comparable to previous studies. Age, vessel diameter and OPP were the significant factors that influenced the saturation. Arteriolar and venous saturations increased with age while the AVSD did not change significantly.

No MeSH data available.


Related in: MedlinePlus

A normal Oxymap image with the pseudo-colour saturation overlap map (Background image—570 nm).
© Copyright Policy
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4414619&req=5

pone.0126179.g001: A normal Oxymap image with the pseudo-colour saturation overlap map (Background image—570 nm).

Mentions: One experienced photographer obtained standardized images for all the subjects. We obtained 2 images per eye in all the subjects—50°—disk centered (Fig 1) and macula centered. Defocus can cause decrease in contrast and hence alterations in the measured values. We ensured that all the images analysed were in sharp focus.


Normative database of retinal oximetry in Asian Indian eyes.

Mohan A, Dabir S, Yadav NK, Kummelil M, Kumar RS, Shetty R - PLoS ONE (2015)

A normal Oxymap image with the pseudo-colour saturation overlap map (Background image—570 nm).
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4414619&req=5

pone.0126179.g001: A normal Oxymap image with the pseudo-colour saturation overlap map (Background image—570 nm).
Mentions: One experienced photographer obtained standardized images for all the subjects. We obtained 2 images per eye in all the subjects—50°—disk centered (Fig 1) and macula centered. Defocus can cause decrease in contrast and hence alterations in the measured values. We ensured that all the images analysed were in sharp focus.

Bottom Line: There was no significant change in the arterio-venous saturation difference (AVSD).Age, vessel diameter and OPP were the significant factors that influenced the saturation.Arteriolar and venous saturations increased with age while the AVSD did not change significantly.

View Article: PubMed Central - PubMed

Affiliation: Narayana Nethralaya, Post Graduate Institute of Ophthalmology, Bangalore, India.

ABSTRACT

Objective: To study the oxygen saturation profile in normal Asian Indian eyes.

Design: A cross sectional prospective study.

Subjects: Ninety eight consecutive patients presenting to our hospital with best corrected distance visual acuity (BCVA) of 20/20 and a normal ophthalmic examination were included in the study. Patients having any ocular or systemic disease were excluded from the study.

Materials and methods: Oximetry was performed on all subjects with the Oxymap T1 retinal oximeter (Oxymap hf, Reykjavik, Iceland).

Main outcome measures: The images were analysed for oxygen saturation and diameter.

Results: The mean age was 33 years (Range: 18-63; SD: 12.4). The average arteriolar saturation was 90.3 ± 6.6% and the venous saturation was 56.9% ± 6.3. The average A-V (arterio-venous) difference was 33.2% ± 5.2. There was an increase in arteriolar (R2 = 0.264; p=0.001) and venous saturation (R2 = 0.151; p=0.001) with age. There was no significant change in the arterio-venous saturation difference (AVSD). The inferotemporal quadrant had the lowest saturations. Age correlated positively with ocular perfusion pressure (OPP)(R2 = 0.07; p=0.007). OPP correlated positively with global arteriolar saturation (R2=0.057, p=0.018).

Conclusion: This study provides the normative database for an Indian population and is comparable to previous studies. Age, vessel diameter and OPP were the significant factors that influenced the saturation. Arteriolar and venous saturations increased with age while the AVSD did not change significantly.

No MeSH data available.


Related in: MedlinePlus