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Cost-effectiveness of Out-of-Hospital Continuous Positive Airway Pressure for Acute Respiratory Failure.

Thokala P, Goodacre S, Ward M, Penn-Ashman J, Perkins GD - Ann Emerg Med (2015)

Bottom Line: The patients who survived accrued lifetime quality-adjusted life-years (QALYs) and health care costs according to their age and sex.Costs were accrued through intervention and hospital treatment costs, which depended on patient outcomes.All results were converted into US dollars, using the Organisation for Economic Co-operation and Development purchasing power parities rates.

View Article: PubMed Central - PubMed

Affiliation: School of Health and Related Research, University of Sheffield, Sheffield, United Kingdom. Electronic address: p.thokala@sheffield.ac.uk.

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Related in: MedlinePlus

Cost-effectiveness plane for the base-case economic analysis. ICER, Incremental cost-effectiveness ratio; QALY, quality-adjusted life-years.
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fig2: Cost-effectiveness plane for the base-case economic analysis. ICER, Incremental cost-effectiveness ratio; QALY, quality-adjusted life-years.

Mentions: The total costs of out-of-hospital CPAP are higher than those of usual care (£16,895 versus £14,863, or $24,497 versus $21,551), but 0.099 QALYs are gained per patient treated (1.513 versus 1.414). The mean incremental cost-effectiveness ratio of out-of-hospital CPAP compared with standard care in the base case analysis is £20,514 per QALY ($29,720/QALY). It therefore costs the health service £20,514 ($29,720) to buy each additional QALY with out-of-hospital CPAP. Figure 2 shows the uncertainty associated with this estimate by plotting samples of mean incremental costs and QALYs. There is substantial uncertainty, with samples falling equally on either side of the red line, indicating the £20,000 per QALY ($29,000/QALY) threshold and a 49.5% probability of out-of-hospital CPAP’s being cost-effective at this threshold.


Cost-effectiveness of Out-of-Hospital Continuous Positive Airway Pressure for Acute Respiratory Failure.

Thokala P, Goodacre S, Ward M, Penn-Ashman J, Perkins GD - Ann Emerg Med (2015)

Cost-effectiveness plane for the base-case economic analysis. ICER, Incremental cost-effectiveness ratio; QALY, quality-adjusted life-years.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4414542&req=5

fig2: Cost-effectiveness plane for the base-case economic analysis. ICER, Incremental cost-effectiveness ratio; QALY, quality-adjusted life-years.
Mentions: The total costs of out-of-hospital CPAP are higher than those of usual care (£16,895 versus £14,863, or $24,497 versus $21,551), but 0.099 QALYs are gained per patient treated (1.513 versus 1.414). The mean incremental cost-effectiveness ratio of out-of-hospital CPAP compared with standard care in the base case analysis is £20,514 per QALY ($29,720/QALY). It therefore costs the health service £20,514 ($29,720) to buy each additional QALY with out-of-hospital CPAP. Figure 2 shows the uncertainty associated with this estimate by plotting samples of mean incremental costs and QALYs. There is substantial uncertainty, with samples falling equally on either side of the red line, indicating the £20,000 per QALY ($29,000/QALY) threshold and a 49.5% probability of out-of-hospital CPAP’s being cost-effective at this threshold.

Bottom Line: The patients who survived accrued lifetime quality-adjusted life-years (QALYs) and health care costs according to their age and sex.Costs were accrued through intervention and hospital treatment costs, which depended on patient outcomes.All results were converted into US dollars, using the Organisation for Economic Co-operation and Development purchasing power parities rates.

View Article: PubMed Central - PubMed

Affiliation: School of Health and Related Research, University of Sheffield, Sheffield, United Kingdom. Electronic address: p.thokala@sheffield.ac.uk.

Show MeSH
Related in: MedlinePlus