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Multiple metastases of soft tissue visualized by technetium-99m-methylene diphosphonate scintigraphy: a case report.

Liberatore M, Megna V, Patrizi G, Giannotti D, Semproni CP, Rebonato S, Barchetti F, Gallo P, Miscusi G - J Med Case Rep (2014)

Bottom Line: Lungs and liver are the most common sites of colorectal cancer metastases after regional lymph nodes, but metastases to unusual sites are reported.We present the case of a 29-year-old Caucasian man affected by colon adenocarcinoma with multiple soft tissue metastases visualized by magnetic resonance imaging, computed tomography scan and scintigraphic bone scan.Our experience suggests that, in the presence of colon adenocarcinoma, a bone scan could be a sensible tool to highlight bone lesions or heterotopic bone nidus in soft tissues and that any subcutaneous lesion should be resected to avoid underestimating a potential malignancy.

View Article: PubMed Central - PubMed

Affiliation: Department of Surgical Sciences, "Sapienza" - University of Rome, Viale Regina Elena 324, 00161, Rome, Italy. maurlib@tin.it.

ABSTRACT

Introduction: Lungs and liver are the most common sites of colorectal cancer metastases after regional lymph nodes, but metastases to unusual sites are reported. Heterotopic bone formation in soft tissues from colorectal cancer is a rare metastatic occurrence.

Case presentation: We present the case of a 29-year-old Caucasian man affected by colon adenocarcinoma with multiple soft tissue metastases visualized by magnetic resonance imaging, computed tomography scan and scintigraphic bone scan. We suppose that these findings can be due to the fact that the tracer is concentrated in the ossification nidus of soft metastases.

Conclusions: Our experience suggests that, in the presence of colon adenocarcinoma, a bone scan could be a sensible tool to highlight bone lesions or heterotopic bone nidus in soft tissues and that any subcutaneous lesion should be resected to avoid underestimating a potential malignancy.

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Related in: MedlinePlus

Bone scan. Different areas of concentration of the radiopharmaceutical are evident in the soft tissues of the upper and lower limbs and of the pelvis, while the skeletal tissue is undamaged.
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Fig2: Bone scan. Different areas of concentration of the radiopharmaceutical are evident in the soft tissues of the upper and lower limbs and of the pelvis, while the skeletal tissue is undamaged.

Mentions: Meanwhile, he underwent a whole body scintigraphic scan (FigureĀ 2) that showed several areas of increased uptake of osteotropic tracer in soft tissues, especially in his lower and upper limbs and in his pelvis without evidence of increased uptake in his bones. These areas of hyperfixation of osteotropic tracer corresponded to the nodules observed in the CT scan.Figure 1


Multiple metastases of soft tissue visualized by technetium-99m-methylene diphosphonate scintigraphy: a case report.

Liberatore M, Megna V, Patrizi G, Giannotti D, Semproni CP, Rebonato S, Barchetti F, Gallo P, Miscusi G - J Med Case Rep (2014)

Bone scan. Different areas of concentration of the radiopharmaceutical are evident in the soft tissues of the upper and lower limbs and of the pelvis, while the skeletal tissue is undamaged.
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC4414277&req=5

Fig2: Bone scan. Different areas of concentration of the radiopharmaceutical are evident in the soft tissues of the upper and lower limbs and of the pelvis, while the skeletal tissue is undamaged.
Mentions: Meanwhile, he underwent a whole body scintigraphic scan (FigureĀ 2) that showed several areas of increased uptake of osteotropic tracer in soft tissues, especially in his lower and upper limbs and in his pelvis without evidence of increased uptake in his bones. These areas of hyperfixation of osteotropic tracer corresponded to the nodules observed in the CT scan.Figure 1

Bottom Line: Lungs and liver are the most common sites of colorectal cancer metastases after regional lymph nodes, but metastases to unusual sites are reported.We present the case of a 29-year-old Caucasian man affected by colon adenocarcinoma with multiple soft tissue metastases visualized by magnetic resonance imaging, computed tomography scan and scintigraphic bone scan.Our experience suggests that, in the presence of colon adenocarcinoma, a bone scan could be a sensible tool to highlight bone lesions or heterotopic bone nidus in soft tissues and that any subcutaneous lesion should be resected to avoid underestimating a potential malignancy.

View Article: PubMed Central - PubMed

Affiliation: Department of Surgical Sciences, "Sapienza" - University of Rome, Viale Regina Elena 324, 00161, Rome, Italy. maurlib@tin.it.

ABSTRACT

Introduction: Lungs and liver are the most common sites of colorectal cancer metastases after regional lymph nodes, but metastases to unusual sites are reported. Heterotopic bone formation in soft tissues from colorectal cancer is a rare metastatic occurrence.

Case presentation: We present the case of a 29-year-old Caucasian man affected by colon adenocarcinoma with multiple soft tissue metastases visualized by magnetic resonance imaging, computed tomography scan and scintigraphic bone scan. We suppose that these findings can be due to the fact that the tracer is concentrated in the ossification nidus of soft metastases.

Conclusions: Our experience suggests that, in the presence of colon adenocarcinoma, a bone scan could be a sensible tool to highlight bone lesions or heterotopic bone nidus in soft tissues and that any subcutaneous lesion should be resected to avoid underestimating a potential malignancy.

Show MeSH
Related in: MedlinePlus