Embryonic expression of endogenous retroviral RNAs in somatic tissues adjacent to the Oikopleura germline.
Bottom Line: Tor Env proteins are membrane-associated glycoproteins which exhibit some features of viral membrane fusion proteins.Such embryonic expression depends on determinants present in the Tor elements and not on their surrounding genomic environment.Our study shows that unusual modes of transcription and expression close to the germline may contribute to the proliferation of Tor elements.
Affiliation: Sars International Centre for Marine Molecular Biology, University of Bergen, Bergen, N-5008, Norway email@example.com.Show MeSH
Related in: MedlinePlus
Mentions: Using a fully assembled genome sequence representing two distinct haplotypes (7), we detected Tor sequences in 167 genomic scaffolds and identified 38 elements carrying a candidate env gene. Phylogenetic analyses of Pol using Maximum-Likelihood or Neighbour-Joining methods, reproducibly revealed Tor1, Tor2, Tor3a, Tor3b, Tor4a and Tor4b groups (Figure 1A). Their positions relative to other gypsy elements were variable and weakly supported. In Tor4b elements, we systematically found a space between pol and env genes (Figure 2A). Half of the Tor elements with env belong to Tor3a, with the others belonging to Tor3b and 4b. A few Tor elements without env were also found in these groups.
Affiliation: Sars International Centre for Marine Molecular Biology, University of Bergen, Bergen, N-5008, Norway firstname.lastname@example.org.