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Age-related responses in circulating markers of redox status in healthy adolescents and adults during the course of a training macrocycle.

Zalavras A, Fatouros IG, Deli CK, Draganidis D, Theodorou AA, Soulas D, Koutsioras Y, Koutedakis Y, Jamurtas AZ - Oxid Med Cell Longev (2015)

Bottom Line: Redox status changes during an annual training cycle in young and adult track and field athletes and possible differences between the two age groups were assessed.Forty-six individuals (24 children and 22 adults) were assigned to four groups: trained adolescents, (TAD, N = 13), untrained adolescents (UAD, N = 11), trained adults (TA, N = 12), and untrained adults (UA, N = 10).These results suggest that acute exercise, age, and training modulate the antioxidant reserves of the body.

View Article: PubMed Central - PubMed

Affiliation: Department of Physical Education & Sport Science, University of Thessaly, Karies, 42100 Trikala, Greece.

ABSTRACT
Redox status changes during an annual training cycle in young and adult track and field athletes and possible differences between the two age groups were assessed. Forty-six individuals (24 children and 22 adults) were assigned to four groups: trained adolescents, (TAD, N = 13), untrained adolescents (UAD, N = 11), trained adults (TA, N = 12), and untrained adults (UA, N = 10). Aerobic capacity and redox status related variables [total antioxidant capacity (TAC), glutathione (GSH), catalase activity, TBARS, protein carbonyls (PC), uric acid, and bilirubin] were assessed at rest and in response to a time-trial bout before training, at mid- and posttraining. TAC, catalase activity, TBARS, PC, uric acid, and bilirubin increased and GSH declined in all groups in response to acute exercise independent of training status and age. Training improved aerobic capacity, TAC, and GSH at rest and in response to exercise. Age affected basal and exercise-induced responses since adults demonstrated a greater TAC and GSH levels at rest and a greater rise of TBARS, protein carbonyls, and TAC and decline of GSH in response to exercise. Catalase activity, uric acid, and bilirubin responses were comparable among groups. These results suggest that acute exercise, age, and training modulate the antioxidant reserves of the body.

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Changes of protein carbonyls in response to acute exercise and training in adolescents and adult participants. PC, protein carbonyls; h, hour; TAD, trained adolescents; TA, trained adults; UAD, untrained adolescents; UA, untrained adults; 1significant (P < 0.05) difference with baseline values at rest; 3significant (P < 0.05) difference between untrained adolescents and untrained adults at the corresponding time point; 4significant (P < 0.05) difference between trained and untrained adolescents at the corresponding time point; 5significant (P < 0.05) difference between trained and untrained adults at the corresponding time point.
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fig3: Changes of protein carbonyls in response to acute exercise and training in adolescents and adult participants. PC, protein carbonyls; h, hour; TAD, trained adolescents; TA, trained adults; UAD, untrained adolescents; UA, untrained adults; 1significant (P < 0.05) difference with baseline values at rest; 3significant (P < 0.05) difference between untrained adolescents and untrained adults at the corresponding time point; 4significant (P < 0.05) difference between trained and untrained adolescents at the corresponding time point; 5significant (P < 0.05) difference between trained and untrained adults at the corresponding time point.

Mentions: Exercise increased (P < 0.001) PC concentration (at pretraining, midtraining, and posttraining; Figure 3) and TBARS (at pretraining, midtraining, and posttraining; Figure 4) in all groups immediately after exercise. Both TBARS and PC remained significantly above resting values 1 h postexercise in all groups (except for TAD at midtraining; Figure 3).


Age-related responses in circulating markers of redox status in healthy adolescents and adults during the course of a training macrocycle.

Zalavras A, Fatouros IG, Deli CK, Draganidis D, Theodorou AA, Soulas D, Koutsioras Y, Koutedakis Y, Jamurtas AZ - Oxid Med Cell Longev (2015)

Changes of protein carbonyls in response to acute exercise and training in adolescents and adult participants. PC, protein carbonyls; h, hour; TAD, trained adolescents; TA, trained adults; UAD, untrained adolescents; UA, untrained adults; 1significant (P < 0.05) difference with baseline values at rest; 3significant (P < 0.05) difference between untrained adolescents and untrained adults at the corresponding time point; 4significant (P < 0.05) difference between trained and untrained adolescents at the corresponding time point; 5significant (P < 0.05) difference between trained and untrained adults at the corresponding time point.
© Copyright Policy - open-access
Related In: Results  -  Collection

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getmorefigures.php?uid=PMC4402481&req=5

fig3: Changes of protein carbonyls in response to acute exercise and training in adolescents and adult participants. PC, protein carbonyls; h, hour; TAD, trained adolescents; TA, trained adults; UAD, untrained adolescents; UA, untrained adults; 1significant (P < 0.05) difference with baseline values at rest; 3significant (P < 0.05) difference between untrained adolescents and untrained adults at the corresponding time point; 4significant (P < 0.05) difference between trained and untrained adolescents at the corresponding time point; 5significant (P < 0.05) difference between trained and untrained adults at the corresponding time point.
Mentions: Exercise increased (P < 0.001) PC concentration (at pretraining, midtraining, and posttraining; Figure 3) and TBARS (at pretraining, midtraining, and posttraining; Figure 4) in all groups immediately after exercise. Both TBARS and PC remained significantly above resting values 1 h postexercise in all groups (except for TAD at midtraining; Figure 3).

Bottom Line: Redox status changes during an annual training cycle in young and adult track and field athletes and possible differences between the two age groups were assessed.Forty-six individuals (24 children and 22 adults) were assigned to four groups: trained adolescents, (TAD, N = 13), untrained adolescents (UAD, N = 11), trained adults (TA, N = 12), and untrained adults (UA, N = 10).These results suggest that acute exercise, age, and training modulate the antioxidant reserves of the body.

View Article: PubMed Central - PubMed

Affiliation: Department of Physical Education & Sport Science, University of Thessaly, Karies, 42100 Trikala, Greece.

ABSTRACT
Redox status changes during an annual training cycle in young and adult track and field athletes and possible differences between the two age groups were assessed. Forty-six individuals (24 children and 22 adults) were assigned to four groups: trained adolescents, (TAD, N = 13), untrained adolescents (UAD, N = 11), trained adults (TA, N = 12), and untrained adults (UA, N = 10). Aerobic capacity and redox status related variables [total antioxidant capacity (TAC), glutathione (GSH), catalase activity, TBARS, protein carbonyls (PC), uric acid, and bilirubin] were assessed at rest and in response to a time-trial bout before training, at mid- and posttraining. TAC, catalase activity, TBARS, PC, uric acid, and bilirubin increased and GSH declined in all groups in response to acute exercise independent of training status and age. Training improved aerobic capacity, TAC, and GSH at rest and in response to exercise. Age affected basal and exercise-induced responses since adults demonstrated a greater TAC and GSH levels at rest and a greater rise of TBARS, protein carbonyls, and TAC and decline of GSH in response to exercise. Catalase activity, uric acid, and bilirubin responses were comparable among groups. These results suggest that acute exercise, age, and training modulate the antioxidant reserves of the body.

Show MeSH
Related in: MedlinePlus