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Chronic kidney disease as a risk factor for incident gout among men and women: retrospective cohort study using data from the Framingham Heart Study.

Wang W, Bhole VM, Krishnan E - BMJ Open (2015)

Bottom Line: Excluding patients who had CKD in the first visit from this study, 2159 men and 2558 women were selected covering a 54-year period (1948-2002).Additional analyses using alternate definitions for CKD and cross-sectional study did not change the results.Sensitivity analysis suggested that the observed findings might be an underestimate of the true relative risk.

View Article: PubMed Central - PubMed

Affiliation: Stanford University School of Medicine, Palo Alto, California, USA.

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Related in: MedlinePlus

Kaplan-Meier failure estimates for incident chronic kidney disease (CKD) to incident gout among participants who developed incident CKD after the baseline visit and those who never developed CKD in the original Framingham Heart Study cohort.
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BMJOPEN2014006843F1: Kaplan-Meier failure estimates for incident chronic kidney disease (CKD) to incident gout among participants who developed incident CKD after the baseline visit and those who never developed CKD in the original Framingham Heart Study cohort.

Mentions: The incidence rate of gout was 6.82 (95% CI 5.10 to 9.10) per 1000 person-years among those with CKD and 2.43 (95% CI 2.18 to 2.71) among those without. Table 2 shows the incidence rates stratified by gender. The incidence rate in the CKD group for men was 10.24 (95% CI 7.02 to 14.93) and for women was 4.62 (95% CI 2.95 to 7.24). There were relatively few cases of gout in the first 20 years of follow-up. Figure 1 shows the Kaplan-Meier failure estimates for gout.


Chronic kidney disease as a risk factor for incident gout among men and women: retrospective cohort study using data from the Framingham Heart Study.

Wang W, Bhole VM, Krishnan E - BMJ Open (2015)

Kaplan-Meier failure estimates for incident chronic kidney disease (CKD) to incident gout among participants who developed incident CKD after the baseline visit and those who never developed CKD in the original Framingham Heart Study cohort.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4401834&req=5

BMJOPEN2014006843F1: Kaplan-Meier failure estimates for incident chronic kidney disease (CKD) to incident gout among participants who developed incident CKD after the baseline visit and those who never developed CKD in the original Framingham Heart Study cohort.
Mentions: The incidence rate of gout was 6.82 (95% CI 5.10 to 9.10) per 1000 person-years among those with CKD and 2.43 (95% CI 2.18 to 2.71) among those without. Table 2 shows the incidence rates stratified by gender. The incidence rate in the CKD group for men was 10.24 (95% CI 7.02 to 14.93) and for women was 4.62 (95% CI 2.95 to 7.24). There were relatively few cases of gout in the first 20 years of follow-up. Figure 1 shows the Kaplan-Meier failure estimates for gout.

Bottom Line: Excluding patients who had CKD in the first visit from this study, 2159 men and 2558 women were selected covering a 54-year period (1948-2002).Additional analyses using alternate definitions for CKD and cross-sectional study did not change the results.Sensitivity analysis suggested that the observed findings might be an underestimate of the true relative risk.

View Article: PubMed Central - PubMed

Affiliation: Stanford University School of Medicine, Palo Alto, California, USA.

Show MeSH
Related in: MedlinePlus