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Dual logic and cerebral coordinates for reciprocal interaction in eye contact.

Lee RF - PLoS ONE (2015)

Bottom Line: Elucidated by dual logic deductions, the cerebral coordinate for reciprocal interaction suggests: the exogenous and endogenous systems consist of the empathy network and the mentalization network respectively; the default-mode network emerges from the resting state to activation in the endogenous system during reciprocal interaction; the cingulate plays an essential role in the emergence from the exogenous system to the endogenous system.Overall, the dual logic deductions are supported by the dfMRI experimental results and are consistent with current literature.Both the theoretical framework and experimental method set the stage to formally apply the scientific method in studying complex social interaction.

View Article: PubMed Central - PubMed

Affiliation: Princeton Neuroscience Institute, Princeton University, Princeton, New Jersey, United States of America.

ABSTRACT
In order to scientifically study the human brain's response to face-to-face social interaction, the scientific method itself needs to be reconsidered so that both quantitative observation and symbolic reasoning can be adapted to the situation where the observer is also observed. In light of the recent development of dyadic fMRI which can directly observe dyadic brain interacting in one MRI scanner, this paper aims to establish a new form of logic, dual logic, which provides a theoretical platform for deductive reasoning in a complementary dual system with emergence mechanism. Applying the dual logic in the dfMRI experimental design and data analysis, the exogenous and endogenous dual systems in the BOLD responses can be identified; the non-reciprocal responses in the dual system can be suppressed; a cerebral coordinate for reciprocal interaction can be generated. Elucidated by dual logic deductions, the cerebral coordinate for reciprocal interaction suggests: the exogenous and endogenous systems consist of the empathy network and the mentalization network respectively; the default-mode network emerges from the resting state to activation in the endogenous system during reciprocal interaction; the cingulate plays an essential role in the emergence from the exogenous system to the endogenous system. Overall, the dual logic deductions are supported by the dfMRI experimental results and are consistent with current literature. Both the theoretical framework and experimental method set the stage to formally apply the scientific method in studying complex social interaction.

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Related in: MedlinePlus

One of the dyadic brain-to-brain coupling modes.The (a) is one of the independent components derived from the 19 data sets in the task A by group-level ICA. The (b) is the 2D matrix representation of the coupling mode after the IC is projected onto the CCRI. Note that each axis has real and imaginary regions that correspond the exogenous and endogenous labels respectively. All complex numbers and their corresponding labels are listed in the Fig 4e and 4f. Here the vertical axis is for right subjects and the horizontal axis is for left subjects. The (c) and (d) are the temporal course and the frequency response of the synchronized process that represented by this IC.
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pone.0121791.g005: One of the dyadic brain-to-brain coupling modes.The (a) is one of the independent components derived from the 19 data sets in the task A by group-level ICA. The (b) is the 2D matrix representation of the coupling mode after the IC is projected onto the CCRI. Note that each axis has real and imaginary regions that correspond the exogenous and endogenous labels respectively. All complex numbers and their corresponding labels are listed in the Fig 4e and 4f. Here the vertical axis is for right subjects and the horizontal axis is for left subjects. The (c) and (d) are the temporal course and the frequency response of the synchronized process that represented by this IC.

Mentions: The 19 dyadic data sets from the task A were processed in following three steps: First, since FSL can only handle monadic data, in order to assign labels to a dyadic IC with FSL, the dyadic data was first split and preprocessed, then the left and right monadic data were registered to the rotated left and right MNI152 standard templates respectively by using the same procedure as in the group GLM, then merged to form a registered dyadic data set. Second, group level tensor-ICA for all 19 registered dyadic data sets was computed by FSL/melodic and yielded 35 ICs. Fig 5a selectively displays one of the 35 ICs. Third, in order to project the ICs onto the CCRI, each dyadic IC was split into two monadic data sets again. The split ICs for the left and right subjects were separately multiplied by the properly oriented CCRI first, and then processed for atlas labeling. The activated labels for the right subjects were indexed as a vertical axis. The activated labels for the left subjects were indexed as a horizontal axis. In this way, each coupling mode can be quantified by a matrix based on the labels in the CCRI, as shown in Fig 5b.


Dual logic and cerebral coordinates for reciprocal interaction in eye contact.

Lee RF - PLoS ONE (2015)

One of the dyadic brain-to-brain coupling modes.The (a) is one of the independent components derived from the 19 data sets in the task A by group-level ICA. The (b) is the 2D matrix representation of the coupling mode after the IC is projected onto the CCRI. Note that each axis has real and imaginary regions that correspond the exogenous and endogenous labels respectively. All complex numbers and their corresponding labels are listed in the Fig 4e and 4f. Here the vertical axis is for right subjects and the horizontal axis is for left subjects. The (c) and (d) are the temporal course and the frequency response of the synchronized process that represented by this IC.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4401735&req=5

pone.0121791.g005: One of the dyadic brain-to-brain coupling modes.The (a) is one of the independent components derived from the 19 data sets in the task A by group-level ICA. The (b) is the 2D matrix representation of the coupling mode after the IC is projected onto the CCRI. Note that each axis has real and imaginary regions that correspond the exogenous and endogenous labels respectively. All complex numbers and their corresponding labels are listed in the Fig 4e and 4f. Here the vertical axis is for right subjects and the horizontal axis is for left subjects. The (c) and (d) are the temporal course and the frequency response of the synchronized process that represented by this IC.
Mentions: The 19 dyadic data sets from the task A were processed in following three steps: First, since FSL can only handle monadic data, in order to assign labels to a dyadic IC with FSL, the dyadic data was first split and preprocessed, then the left and right monadic data were registered to the rotated left and right MNI152 standard templates respectively by using the same procedure as in the group GLM, then merged to form a registered dyadic data set. Second, group level tensor-ICA for all 19 registered dyadic data sets was computed by FSL/melodic and yielded 35 ICs. Fig 5a selectively displays one of the 35 ICs. Third, in order to project the ICs onto the CCRI, each dyadic IC was split into two monadic data sets again. The split ICs for the left and right subjects were separately multiplied by the properly oriented CCRI first, and then processed for atlas labeling. The activated labels for the right subjects were indexed as a vertical axis. The activated labels for the left subjects were indexed as a horizontal axis. In this way, each coupling mode can be quantified by a matrix based on the labels in the CCRI, as shown in Fig 5b.

Bottom Line: Elucidated by dual logic deductions, the cerebral coordinate for reciprocal interaction suggests: the exogenous and endogenous systems consist of the empathy network and the mentalization network respectively; the default-mode network emerges from the resting state to activation in the endogenous system during reciprocal interaction; the cingulate plays an essential role in the emergence from the exogenous system to the endogenous system.Overall, the dual logic deductions are supported by the dfMRI experimental results and are consistent with current literature.Both the theoretical framework and experimental method set the stage to formally apply the scientific method in studying complex social interaction.

View Article: PubMed Central - PubMed

Affiliation: Princeton Neuroscience Institute, Princeton University, Princeton, New Jersey, United States of America.

ABSTRACT
In order to scientifically study the human brain's response to face-to-face social interaction, the scientific method itself needs to be reconsidered so that both quantitative observation and symbolic reasoning can be adapted to the situation where the observer is also observed. In light of the recent development of dyadic fMRI which can directly observe dyadic brain interacting in one MRI scanner, this paper aims to establish a new form of logic, dual logic, which provides a theoretical platform for deductive reasoning in a complementary dual system with emergence mechanism. Applying the dual logic in the dfMRI experimental design and data analysis, the exogenous and endogenous dual systems in the BOLD responses can be identified; the non-reciprocal responses in the dual system can be suppressed; a cerebral coordinate for reciprocal interaction can be generated. Elucidated by dual logic deductions, the cerebral coordinate for reciprocal interaction suggests: the exogenous and endogenous systems consist of the empathy network and the mentalization network respectively; the default-mode network emerges from the resting state to activation in the endogenous system during reciprocal interaction; the cingulate plays an essential role in the emergence from the exogenous system to the endogenous system. Overall, the dual logic deductions are supported by the dfMRI experimental results and are consistent with current literature. Both the theoretical framework and experimental method set the stage to formally apply the scientific method in studying complex social interaction.

Show MeSH
Related in: MedlinePlus