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Dual logic and cerebral coordinates for reciprocal interaction in eye contact.

Lee RF - PLoS ONE (2015)

Bottom Line: Elucidated by dual logic deductions, the cerebral coordinate for reciprocal interaction suggests: the exogenous and endogenous systems consist of the empathy network and the mentalization network respectively; the default-mode network emerges from the resting state to activation in the endogenous system during reciprocal interaction; the cingulate plays an essential role in the emergence from the exogenous system to the endogenous system.Overall, the dual logic deductions are supported by the dfMRI experimental results and are consistent with current literature.Both the theoretical framework and experimental method set the stage to formally apply the scientific method in studying complex social interaction.

View Article: PubMed Central - PubMed

Affiliation: Princeton Neuroscience Institute, Princeton University, Princeton, New Jersey, United States of America.

ABSTRACT
In order to scientifically study the human brain's response to face-to-face social interaction, the scientific method itself needs to be reconsidered so that both quantitative observation and symbolic reasoning can be adapted to the situation where the observer is also observed. In light of the recent development of dyadic fMRI which can directly observe dyadic brain interacting in one MRI scanner, this paper aims to establish a new form of logic, dual logic, which provides a theoretical platform for deductive reasoning in a complementary dual system with emergence mechanism. Applying the dual logic in the dfMRI experimental design and data analysis, the exogenous and endogenous dual systems in the BOLD responses can be identified; the non-reciprocal responses in the dual system can be suppressed; a cerebral coordinate for reciprocal interaction can be generated. Elucidated by dual logic deductions, the cerebral coordinate for reciprocal interaction suggests: the exogenous and endogenous systems consist of the empathy network and the mentalization network respectively; the default-mode network emerges from the resting state to activation in the endogenous system during reciprocal interaction; the cingulate plays an essential role in the emergence from the exogenous system to the endogenous system. Overall, the dual logic deductions are supported by the dfMRI experimental results and are consistent with current literature. Both the theoretical framework and experimental method set the stage to formally apply the scientific method in studying complex social interaction.

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Related in: MedlinePlus

The reciprocal BOLD responses due to eye contact.The (a) is the exogenous responses in which Ω+ = 1 when (x = 1, y = 0); the (b) is the endogenous responses in which Ω- = 1 when (ξ = 1, ψ = 0) and (ξ = 0, ψ = 0). Here the (c) and (d) are the three orthogonal sections of the (a) and (b) respectively; the (e) and (f) are the probabilistic atlas label distributions for the exogenous-endogenous dual system, where the exogenous labels are indexed by real number, and the endogenous labels are indexed by imaginary number.
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pone.0121791.g004: The reciprocal BOLD responses due to eye contact.The (a) is the exogenous responses in which Ω+ = 1 when (x = 1, y = 0); the (b) is the endogenous responses in which Ω- = 1 when (ξ = 1, ψ = 0) and (ξ = 0, ψ = 0). Here the (c) and (d) are the three orthogonal sections of the (a) and (b) respectively; the (e) and (f) are the probabilistic atlas label distributions for the exogenous-endogenous dual system, where the exogenous labels are indexed by real number, and the endogenous labels are indexed by imaginary number.

Mentions: After data preprocessing, Group GLM analysis was performed on the preprocessed monadic data sets from both task A and B. The hemodynamic response functions (HRF) were the block waveforms in Fig 1c convolved by the first three eigen-components in the linear optimal basis set [23]. The group average GLM for ΩA and ΩB were shown in Fig 3a and 3b. The paired t-test comparison for Ω+ and Ω- were shown in Fig 4a–4d. The activation labeling was based on the “Harvard-Oxford cortical structural atlas” and the “Harvard-Oxford subcortical structural atlas,” which are built-in features of FSL. In the end, the masks of Ω+ and Ω- (1 for activation, 0 for no activation) became the CCRI. The atlas labels of Ω+ and Ω- became the coordinate ticks in the CCRI, where exogenous and endogenous labels are indexed by real and imaginary numbers respectively, as shown in Fig 4e and 4f.


Dual logic and cerebral coordinates for reciprocal interaction in eye contact.

Lee RF - PLoS ONE (2015)

The reciprocal BOLD responses due to eye contact.The (a) is the exogenous responses in which Ω+ = 1 when (x = 1, y = 0); the (b) is the endogenous responses in which Ω- = 1 when (ξ = 1, ψ = 0) and (ξ = 0, ψ = 0). Here the (c) and (d) are the three orthogonal sections of the (a) and (b) respectively; the (e) and (f) are the probabilistic atlas label distributions for the exogenous-endogenous dual system, where the exogenous labels are indexed by real number, and the endogenous labels are indexed by imaginary number.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4401735&req=5

pone.0121791.g004: The reciprocal BOLD responses due to eye contact.The (a) is the exogenous responses in which Ω+ = 1 when (x = 1, y = 0); the (b) is the endogenous responses in which Ω- = 1 when (ξ = 1, ψ = 0) and (ξ = 0, ψ = 0). Here the (c) and (d) are the three orthogonal sections of the (a) and (b) respectively; the (e) and (f) are the probabilistic atlas label distributions for the exogenous-endogenous dual system, where the exogenous labels are indexed by real number, and the endogenous labels are indexed by imaginary number.
Mentions: After data preprocessing, Group GLM analysis was performed on the preprocessed monadic data sets from both task A and B. The hemodynamic response functions (HRF) were the block waveforms in Fig 1c convolved by the first three eigen-components in the linear optimal basis set [23]. The group average GLM for ΩA and ΩB were shown in Fig 3a and 3b. The paired t-test comparison for Ω+ and Ω- were shown in Fig 4a–4d. The activation labeling was based on the “Harvard-Oxford cortical structural atlas” and the “Harvard-Oxford subcortical structural atlas,” which are built-in features of FSL. In the end, the masks of Ω+ and Ω- (1 for activation, 0 for no activation) became the CCRI. The atlas labels of Ω+ and Ω- became the coordinate ticks in the CCRI, where exogenous and endogenous labels are indexed by real and imaginary numbers respectively, as shown in Fig 4e and 4f.

Bottom Line: Elucidated by dual logic deductions, the cerebral coordinate for reciprocal interaction suggests: the exogenous and endogenous systems consist of the empathy network and the mentalization network respectively; the default-mode network emerges from the resting state to activation in the endogenous system during reciprocal interaction; the cingulate plays an essential role in the emergence from the exogenous system to the endogenous system.Overall, the dual logic deductions are supported by the dfMRI experimental results and are consistent with current literature.Both the theoretical framework and experimental method set the stage to formally apply the scientific method in studying complex social interaction.

View Article: PubMed Central - PubMed

Affiliation: Princeton Neuroscience Institute, Princeton University, Princeton, New Jersey, United States of America.

ABSTRACT
In order to scientifically study the human brain's response to face-to-face social interaction, the scientific method itself needs to be reconsidered so that both quantitative observation and symbolic reasoning can be adapted to the situation where the observer is also observed. In light of the recent development of dyadic fMRI which can directly observe dyadic brain interacting in one MRI scanner, this paper aims to establish a new form of logic, dual logic, which provides a theoretical platform for deductive reasoning in a complementary dual system with emergence mechanism. Applying the dual logic in the dfMRI experimental design and data analysis, the exogenous and endogenous dual systems in the BOLD responses can be identified; the non-reciprocal responses in the dual system can be suppressed; a cerebral coordinate for reciprocal interaction can be generated. Elucidated by dual logic deductions, the cerebral coordinate for reciprocal interaction suggests: the exogenous and endogenous systems consist of the empathy network and the mentalization network respectively; the default-mode network emerges from the resting state to activation in the endogenous system during reciprocal interaction; the cingulate plays an essential role in the emergence from the exogenous system to the endogenous system. Overall, the dual logic deductions are supported by the dfMRI experimental results and are consistent with current literature. Both the theoretical framework and experimental method set the stage to formally apply the scientific method in studying complex social interaction.

Show MeSH
Related in: MedlinePlus