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Association of ABO and Rh Blood Groups to Blood-Borne Infections among Blood Donors in Tehran-Iran.

Mohammadali F, Pourfathollah A - Iran. J. Public Health (2014)

Bottom Line: Initial reactive samples were tested in duplicate.Confirmatory tests were performed on all repeatedly reactive donations.The results were subjected to chi square analysis for determination of statistical difference between the values among different categories according to SPSS program.

View Article: PubMed Central - PubMed

Affiliation: 1. Dept. of Hematology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran ; 2. Iranian Blood Transfusion Research Center & Tehran Blood Transfusion Center, Tehran, Iran.

ABSTRACT

Background: The aim of this study was to investigate the prevalence of hepatitis B, hepatitis C, HIV and syphilis infections in blood donors referred to Tehran Blood Transfusion Center (TBTC), and determine any association between blood groups and blood- borne infections between the years of 2005 and 2011.

Methods: This was a retrospective study conducted at TBTC. All of the donor serum samples were screened for HBV, HCV, HIV and syphilis by using third generation ELISA kits and RPR test. Initial reactive samples were tested in duplicate. Confirmatory tests were performed on all repeatedly reactive donations. Blood group was determined by forward and reverse blood grouping. The results were subjected to chi square analysis for determination of statistical difference between the values among different categories according to SPSS program.

Results: Overall, 2031451 donor serum samples were collected in 2005-2011. Totally, 10451 were positive test for HBV, HCV, HIV and syphilis. The overall seroprevalence of HBV, HCV, HIV, and syphilis was 0.39%, 0.11%, 0.005%, and 0.010%, respectively. Hepatitis B and HIV infections were significantly associated with blood group of donors (P <0.05) ; percentage of HIV Ag/Ab was higher in donors who had blood group "A" and percentage of HBs Ag was lower in donors who had blood group O. There was no significant association between Hepatitis C and syphilis infections with ABO and Rh blood groups (P>0.05).

Conclusion: Compared with neighboring countries and the international standards, prevalence of blood-borne infections is relatively low.

No MeSH data available.


Related in: MedlinePlus

Frequency of blood groups among blood donors referred to Tehran Blood Transfusion Center during 2005-2011
© Copyright Policy - open-access
Related In: Results  -  Collection


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Figure 1: Frequency of blood groups among blood donors referred to Tehran Blood Transfusion Center during 2005-2011

Mentions: Over a period of six years (March 2005 to March2011) a total of 2,031,451 donations were collected with an average of 338,575 donations per year. 1,892,835(93.2%) of them were male and 138,616(6.8%) were female. After excluding of Blood group discrepancies, blood group of 2,028,086 donors was determined. Blood group O+ with frequency of 665,943 (32.8%) was commonest and Oh - with frequency of 1 donor (0.00004%) was least frequent among blood donors (Fig. 1). the prevalence of Rh positive and Rh negative was, 89.3% and 10.7%, respectively.


Association of ABO and Rh Blood Groups to Blood-Borne Infections among Blood Donors in Tehran-Iran.

Mohammadali F, Pourfathollah A - Iran. J. Public Health (2014)

Frequency of blood groups among blood donors referred to Tehran Blood Transfusion Center during 2005-2011
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4401062&req=5

Figure 1: Frequency of blood groups among blood donors referred to Tehran Blood Transfusion Center during 2005-2011
Mentions: Over a period of six years (March 2005 to March2011) a total of 2,031,451 donations were collected with an average of 338,575 donations per year. 1,892,835(93.2%) of them were male and 138,616(6.8%) were female. After excluding of Blood group discrepancies, blood group of 2,028,086 donors was determined. Blood group O+ with frequency of 665,943 (32.8%) was commonest and Oh - with frequency of 1 donor (0.00004%) was least frequent among blood donors (Fig. 1). the prevalence of Rh positive and Rh negative was, 89.3% and 10.7%, respectively.

Bottom Line: Initial reactive samples were tested in duplicate.Confirmatory tests were performed on all repeatedly reactive donations.The results were subjected to chi square analysis for determination of statistical difference between the values among different categories according to SPSS program.

View Article: PubMed Central - PubMed

Affiliation: 1. Dept. of Hematology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran ; 2. Iranian Blood Transfusion Research Center & Tehran Blood Transfusion Center, Tehran, Iran.

ABSTRACT

Background: The aim of this study was to investigate the prevalence of hepatitis B, hepatitis C, HIV and syphilis infections in blood donors referred to Tehran Blood Transfusion Center (TBTC), and determine any association between blood groups and blood- borne infections between the years of 2005 and 2011.

Methods: This was a retrospective study conducted at TBTC. All of the donor serum samples were screened for HBV, HCV, HIV and syphilis by using third generation ELISA kits and RPR test. Initial reactive samples were tested in duplicate. Confirmatory tests were performed on all repeatedly reactive donations. Blood group was determined by forward and reverse blood grouping. The results were subjected to chi square analysis for determination of statistical difference between the values among different categories according to SPSS program.

Results: Overall, 2031451 donor serum samples were collected in 2005-2011. Totally, 10451 were positive test for HBV, HCV, HIV and syphilis. The overall seroprevalence of HBV, HCV, HIV, and syphilis was 0.39%, 0.11%, 0.005%, and 0.010%, respectively. Hepatitis B and HIV infections were significantly associated with blood group of donors (P <0.05) ; percentage of HIV Ag/Ab was higher in donors who had blood group "A" and percentage of HBs Ag was lower in donors who had blood group O. There was no significant association between Hepatitis C and syphilis infections with ABO and Rh blood groups (P>0.05).

Conclusion: Compared with neighboring countries and the international standards, prevalence of blood-borne infections is relatively low.

No MeSH data available.


Related in: MedlinePlus