Limits...
Spontaneous coronary artery dissection in polycystic kidney disease.

Klingenberg-Salachova F, Limburg S, Boereboom F - Clin Kidney J (2012)

Bottom Line: We suggest that the genetic disorder in ADPKD is the main cause of instable artery vasculature.Our case also shows that CAD can be missed in the acute phase.The patient received medical management.

View Article: PubMed Central - PubMed

Affiliation: Department of General Medicine, Diakonessenhuis, Utrecht, The Netherlands.

ABSTRACT
Little is known about the association between autosomal-dominant polycystic kidney disease (ADPKD) and coronary artery dissection (CAD). We suggest that the genetic disorder in ADPKD is the main cause of instable artery vasculature. Our case also shows that CAD can be missed in the acute phase. Therefore, we recommend additional investigation in patients with ADPKD presenting with acute chest pain. We report a case of a patient who developed a myocardial infarction due to a spontaneous dissection of the left anterior descending coronary artery. ADPKD was diagnosed during the additional investigation. The patient received medical management.

No MeSH data available.


Related in: MedlinePlus

Electrocardiography on presentation shows a sinus rhythm of 65 beats/minute and ST elevation in V3, II and III.
© Copyright Policy - creative-commons
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4400459&req=5

fig1: Electrocardiography on presentation shows a sinus rhythm of 65 beats/minute and ST elevation in V3, II and III.

Mentions: On physical examination, the blood pressure was 155/102 mmHg and the pulse 72 beats/minute; other vital parameters were normal. Electrocardiography showed a sinus rhythm of 65 beats/minute and ST elevation in the precordial leads (Figure 1). Creatine kinase was 249 U/L, creatine kinase MB was 17.4 U/L and troponin T was 0.21 ng/mL. The other laboratory test results were normal. Twelve hours later, the cardiac enzymes increased to higher levels. Echocardiography revealed a hypokinetic septum and a slightly impaired left ventricular function with an ejection fraction of 45–60%.


Spontaneous coronary artery dissection in polycystic kidney disease.

Klingenberg-Salachova F, Limburg S, Boereboom F - Clin Kidney J (2012)

Electrocardiography on presentation shows a sinus rhythm of 65 beats/minute and ST elevation in V3, II and III.
© Copyright Policy - creative-commons
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4400459&req=5

fig1: Electrocardiography on presentation shows a sinus rhythm of 65 beats/minute and ST elevation in V3, II and III.
Mentions: On physical examination, the blood pressure was 155/102 mmHg and the pulse 72 beats/minute; other vital parameters were normal. Electrocardiography showed a sinus rhythm of 65 beats/minute and ST elevation in the precordial leads (Figure 1). Creatine kinase was 249 U/L, creatine kinase MB was 17.4 U/L and troponin T was 0.21 ng/mL. The other laboratory test results were normal. Twelve hours later, the cardiac enzymes increased to higher levels. Echocardiography revealed a hypokinetic septum and a slightly impaired left ventricular function with an ejection fraction of 45–60%.

Bottom Line: We suggest that the genetic disorder in ADPKD is the main cause of instable artery vasculature.Our case also shows that CAD can be missed in the acute phase.The patient received medical management.

View Article: PubMed Central - PubMed

Affiliation: Department of General Medicine, Diakonessenhuis, Utrecht, The Netherlands.

ABSTRACT
Little is known about the association between autosomal-dominant polycystic kidney disease (ADPKD) and coronary artery dissection (CAD). We suggest that the genetic disorder in ADPKD is the main cause of instable artery vasculature. Our case also shows that CAD can be missed in the acute phase. Therefore, we recommend additional investigation in patients with ADPKD presenting with acute chest pain. We report a case of a patient who developed a myocardial infarction due to a spontaneous dissection of the left anterior descending coronary artery. ADPKD was diagnosed during the additional investigation. The patient received medical management.

No MeSH data available.


Related in: MedlinePlus