Place field repetition and purely local remapping in a multicompartment environment.
Bottom Line: Some studies report that place cells can disambiguate different compartments, while others report that they do not.Second, this repetition does not diminish with extended experience.Third, remapping was found to be purely local for both geometric change and contextual change.
Affiliation: Department of Cognitive, Perceptual and Brain Sciences, Division of Psychology and Language Sciences, Institute of Behavioural Neuroscience, University College London, UK.Show MeSH
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Mentions: In the first—neighborhood—analysis, we assigned neighborhood relations to the compartments as follows: any compartments adjacent to the peak were labeled “1,” any that were next-but-one were labeled “2” and any that were 2 compartments away (for the subset of cells with peak fields in an end compartment) were labeled “3.” For cells in which there were 2 compartments occupying the “1” position, these values were averaged. We then analyzed firing rates as a function of this ordinal distance from the peak-rate compartment for both first day and last day of recording (see Fig. 6A). A 2-factor (day and compartment distance) repeated-measures ANOVA revealed a main effect of compartment distance [F2,64 = 15.1, P < 0.001, but no main effect of day or significant interaction. Unsurprisingly, for both first and last day, post hoc t-tests revealed significant differences in rate when the peak compartment was compared with compartments at a distance of 1 (P < 0.05, Cohen's d for first day = 0.64, Cohen's d for last day = 0.55), 2 (P < 0.05, Cohen's d for first day = 0.77, Cohen's d for last day = 0.76), or 3 compartments from the peak (P < 0.05, Cohen's d for first day = 0.79, Cohen's d for last day = 0.63). However, no other post hoc tests were significant (maximum Cohen's d = 0.22, 1 vs. 2 on last day). Thus, our neighborhood analysis provided no evidence of any modulation of peak rates by distance beyond the peak compartment.Figure 6.
Affiliation: Department of Cognitive, Perceptual and Brain Sciences, Division of Psychology and Language Sciences, Institute of Behavioural Neuroscience, University College London, UK.