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GPU-accelerated framework for intracoronary optical coherence tomography imaging at the push of a button.

Han M, Kim K, Jang SJ, Cho HS, Bouma BE, Oh WY, Ryu S - PLoS ONE (2015)

Bottom Line: To help more accurate diagnosis and monitoring of the disease, many researchers have recently worked on visualization of various coronary microscopic features including stent struts by constructing three-dimensional (3D) volumetric rendering from series of cross-sectional intracoronary FD-OCT images.In this paper, we present the first, to our knowledge, "push-of-a-button" graphics processing unit (GPU)-accelerated framework for intracoronary OCT imaging.Our framework visualizes 3D microstructures of the vessel wall with stent struts from raw binary OCT data acquired by the system digitizer as one seamless process.

View Article: PubMed Central - PubMed

Affiliation: Department of Computer Science, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea.

ABSTRACT
Frequency domain optical coherence tomography (FD-OCT) has become one of the important clinical tools for intracoronary imaging to diagnose and monitor coronary artery disease, which has been one of the leading causes of death. To help more accurate diagnosis and monitoring of the disease, many researchers have recently worked on visualization of various coronary microscopic features including stent struts by constructing three-dimensional (3D) volumetric rendering from series of cross-sectional intracoronary FD-OCT images. In this paper, we present the first, to our knowledge, "push-of-a-button" graphics processing unit (GPU)-accelerated framework for intracoronary OCT imaging. Our framework visualizes 3D microstructures of the vessel wall with stent struts from raw binary OCT data acquired by the system digitizer as one seamless process. The framework reports the state-of-the-art performance; from raw OCT data, it takes 4.7 seconds to provide 3D visualization of a 5-cm-long coronary artery (of size 1600 samples x 1024 A-lines x 260 frames) with stent struts and detection of malapposition automatically at the single push of a button.

No MeSH data available.


Related in: MedlinePlus

Schematic of the intracoronary FD-OCT system.WSL: Wavelength-Swept Laser, FRJ: Fiberoptic Rotary Junction, FS: Frequency Shifter, PDBD: Polarization Diverse Balanced Detection, GPU: Graphics Processing Unit.
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pone.0124192.g001: Schematic of the intracoronary FD-OCT system.WSL: Wavelength-Swept Laser, FRJ: Fiberoptic Rotary Junction, FS: Frequency Shifter, PDBD: Polarization Diverse Balanced Detection, GPU: Graphics Processing Unit.

Mentions: The first module of our framework is an intracoronary FD-OCT system [25, 26], as depicted in Fig 1. A wavelength-swept laser (WSL) centered at 1,300 nm with wavelength tuning range and repetition rate of 120 nm and 110 kHz, respectively, was used as a light source. A frequency shifter (FS) in the reference arm removes the depth degeneracy enabling full-range imaging [27]. Both FD-OCT interference fringes corresponding to two orthogonal polarizations were detected separately by a pair of balanced receivers in polarization diverse balanced detection setup. Signals from each detector were sampled by a two-channel high-speed and high-resolution digitizer (Signatec PX14400, 14 bits, 2 channels) at 180 MS/sec. Each A-line consisted of 1600 sampled data. A pair of cross-sectional images corresponding to a pair of orthogonal polarization channels that consists of 1024 A-lines each was acquired at each longitudinal position of the vessel. Intracoronary imaging was achieved through an endoscopic imaging catheter. The axial and traverse resolutions were 9 μm and 36 μm, respectively. A high-precision and high-speed fiberoptic rotary junction (FRJ) spun the catheter providing 100 cross-sectional images every second.


GPU-accelerated framework for intracoronary optical coherence tomography imaging at the push of a button.

Han M, Kim K, Jang SJ, Cho HS, Bouma BE, Oh WY, Ryu S - PLoS ONE (2015)

Schematic of the intracoronary FD-OCT system.WSL: Wavelength-Swept Laser, FRJ: Fiberoptic Rotary Junction, FS: Frequency Shifter, PDBD: Polarization Diverse Balanced Detection, GPU: Graphics Processing Unit.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4400174&req=5

pone.0124192.g001: Schematic of the intracoronary FD-OCT system.WSL: Wavelength-Swept Laser, FRJ: Fiberoptic Rotary Junction, FS: Frequency Shifter, PDBD: Polarization Diverse Balanced Detection, GPU: Graphics Processing Unit.
Mentions: The first module of our framework is an intracoronary FD-OCT system [25, 26], as depicted in Fig 1. A wavelength-swept laser (WSL) centered at 1,300 nm with wavelength tuning range and repetition rate of 120 nm and 110 kHz, respectively, was used as a light source. A frequency shifter (FS) in the reference arm removes the depth degeneracy enabling full-range imaging [27]. Both FD-OCT interference fringes corresponding to two orthogonal polarizations were detected separately by a pair of balanced receivers in polarization diverse balanced detection setup. Signals from each detector were sampled by a two-channel high-speed and high-resolution digitizer (Signatec PX14400, 14 bits, 2 channels) at 180 MS/sec. Each A-line consisted of 1600 sampled data. A pair of cross-sectional images corresponding to a pair of orthogonal polarization channels that consists of 1024 A-lines each was acquired at each longitudinal position of the vessel. Intracoronary imaging was achieved through an endoscopic imaging catheter. The axial and traverse resolutions were 9 μm and 36 μm, respectively. A high-precision and high-speed fiberoptic rotary junction (FRJ) spun the catheter providing 100 cross-sectional images every second.

Bottom Line: To help more accurate diagnosis and monitoring of the disease, many researchers have recently worked on visualization of various coronary microscopic features including stent struts by constructing three-dimensional (3D) volumetric rendering from series of cross-sectional intracoronary FD-OCT images.In this paper, we present the first, to our knowledge, "push-of-a-button" graphics processing unit (GPU)-accelerated framework for intracoronary OCT imaging.Our framework visualizes 3D microstructures of the vessel wall with stent struts from raw binary OCT data acquired by the system digitizer as one seamless process.

View Article: PubMed Central - PubMed

Affiliation: Department of Computer Science, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea.

ABSTRACT
Frequency domain optical coherence tomography (FD-OCT) has become one of the important clinical tools for intracoronary imaging to diagnose and monitor coronary artery disease, which has been one of the leading causes of death. To help more accurate diagnosis and monitoring of the disease, many researchers have recently worked on visualization of various coronary microscopic features including stent struts by constructing three-dimensional (3D) volumetric rendering from series of cross-sectional intracoronary FD-OCT images. In this paper, we present the first, to our knowledge, "push-of-a-button" graphics processing unit (GPU)-accelerated framework for intracoronary OCT imaging. Our framework visualizes 3D microstructures of the vessel wall with stent struts from raw binary OCT data acquired by the system digitizer as one seamless process. The framework reports the state-of-the-art performance; from raw OCT data, it takes 4.7 seconds to provide 3D visualization of a 5-cm-long coronary artery (of size 1600 samples x 1024 A-lines x 260 frames) with stent struts and detection of malapposition automatically at the single push of a button.

No MeSH data available.


Related in: MedlinePlus