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Diagnosing Psoriatic Arthritis from the Dermatologist's View.

Cho HH, Kim BS - J Lifestyle Med (2013)

Bottom Line: Psoriatic arthritis is a chronic inflammatory arthropathy associated with skin psoriasis.It is considered a unique arthropathy with distinct clinical and radiologic features.Biologic agents, including TNF-α inhibitors and anti-IL12/23 agents, have shown dramatic improvement.

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology, School of Medicine, Pusan National University Hospital, Busan ; Pusan National University Yangsan Hospital, Yangsan, Korea.

ABSTRACT
Psoriatic arthritis is a chronic inflammatory arthropathy associated with skin psoriasis. It is considered a unique arthropathy with distinct clinical and radiologic features. Up to 40% of patients with psoriasis may develop psoriatic arthritis. Psoriasis usually precedes psoriatic arthritis, so dermatologists are in a critical position for screening patients of psoriatic arthritis early in the disease course. Psoriatic arthritis may be challenging to diagnose, especially for dermatologists, because it has an insidious disease course, non-specific symptoms, and no specific biomarkers. Psoriatic arthritis is a polygenic autoimmune disorder of unknown etiology, but immunologic roles have recently been validated. In recent years, treatment modalities have rapidly advanced in the fields of psoriasis and psoriatic arthritis. Biologic agents, including TNF-α inhibitors and anti-IL12/23 agents, have shown dramatic improvement.

No MeSH data available.


Related in: MedlinePlus

Plaque type psoriasis with silvery scales on left arm.
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f2-jlm-03-85: Plaque type psoriasis with silvery scales on left arm.

Mentions: Skin lesions such as psoriasis can be localized, diffuse, guttate, or pustular (Fig 2). There is no specific skin involvement associated with a certain pattern of joint involvement. Thus, patients with any pattern and degree of arthritis can develop psoriasis vulgaris, severe generalized pustular psoriasis, or erythrodermic psoriasis [8]. Iridocyclitis represents the most frequent extra-articular feature, with an estimated prevalence of 2% to 25% of cases [6,7,9,19]. Iridocyclitis is characterized by an acute onset over 1–2 days, eye pain, redness, miosis, photophobia, and vision blurring.


Diagnosing Psoriatic Arthritis from the Dermatologist's View.

Cho HH, Kim BS - J Lifestyle Med (2013)

Plaque type psoriasis with silvery scales on left arm.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4390746&req=5

f2-jlm-03-85: Plaque type psoriasis with silvery scales on left arm.
Mentions: Skin lesions such as psoriasis can be localized, diffuse, guttate, or pustular (Fig 2). There is no specific skin involvement associated with a certain pattern of joint involvement. Thus, patients with any pattern and degree of arthritis can develop psoriasis vulgaris, severe generalized pustular psoriasis, or erythrodermic psoriasis [8]. Iridocyclitis represents the most frequent extra-articular feature, with an estimated prevalence of 2% to 25% of cases [6,7,9,19]. Iridocyclitis is characterized by an acute onset over 1–2 days, eye pain, redness, miosis, photophobia, and vision blurring.

Bottom Line: Psoriatic arthritis is a chronic inflammatory arthropathy associated with skin psoriasis.It is considered a unique arthropathy with distinct clinical and radiologic features.Biologic agents, including TNF-α inhibitors and anti-IL12/23 agents, have shown dramatic improvement.

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology, School of Medicine, Pusan National University Hospital, Busan ; Pusan National University Yangsan Hospital, Yangsan, Korea.

ABSTRACT
Psoriatic arthritis is a chronic inflammatory arthropathy associated with skin psoriasis. It is considered a unique arthropathy with distinct clinical and radiologic features. Up to 40% of patients with psoriasis may develop psoriatic arthritis. Psoriasis usually precedes psoriatic arthritis, so dermatologists are in a critical position for screening patients of psoriatic arthritis early in the disease course. Psoriatic arthritis may be challenging to diagnose, especially for dermatologists, because it has an insidious disease course, non-specific symptoms, and no specific biomarkers. Psoriatic arthritis is a polygenic autoimmune disorder of unknown etiology, but immunologic roles have recently been validated. In recent years, treatment modalities have rapidly advanced in the fields of psoriasis and psoriatic arthritis. Biologic agents, including TNF-α inhibitors and anti-IL12/23 agents, have shown dramatic improvement.

No MeSH data available.


Related in: MedlinePlus